Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   F0T12_RS00270 Genome accession   NZ_CP043812
Coordinates   53431..56532 (-) Length   1033 a.a.
NCBI ID   WP_164824758.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain NG290     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 48431..61532
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F0T12_RS00250 (F0T12_00285) - 49501..49890 (-) 390 WP_003687278.1 endonuclease domain-containing protein -
  F0T12_RS00255 (F0T12_00290) - 50053..50432 (-) 380 Protein_48 VOC family protein -
  F0T12_RS00260 (F0T12_00295) carA 50486..51619 (-) 1134 WP_003687283.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  F0T12_RS00265 (F0T12_00305) - 52333..52617 (-) 285 WP_047918726.1 GIY-YIG nuclease family protein -
  F0T12_RS00270 (F0T12_00315) pilC 53431..56532 (-) 3102 WP_164824758.1 PilC family type IV pilus tip adhesin Machinery gene
  F0T12_RS00275 (F0T12_00320) apbC 58369..59448 (-) 1080 WP_050157562.1 iron-sulfur cluster carrier protein ApbC -
  F0T12_RS00285 (F0T12_00330) - 59815..60324 (+) 510 WP_003687293.1 protein disulfide oxidoreductase -
  F0T12_RS00290 (F0T12_00340) nadR 60665..61105 (+) 441 WP_003687296.1 MarR family adhesin repressor NadR -

Sequence

Protein


Download         Length: 1033 a.a.        Molecular weight: 112825.14 Da        Isoelectric Point: 9.9855

>NTDB_id=385892 F0T12_RS00270 WP_164824758.1 53431..56532(-) (pilC) [Neisseria gonorrhoeae strain NG290]
MNKTLKRRVFRHTALYTAILMFSHTGGGGGQAQARDYAIIMNGRNQPEVKSNVPSSIKDKDRKRTFSHTSQTNWRGQQNN
FISFDNSDELVSQQSGTAVFGTATYLPPYGKVSGFDTDRLKKRNNAVDWIRTTRIALAGYSYEGVVCRSGTGCPKLVYKT
RFSFDNPDLVKNAGKLDRYTDLSRENSPIYKLKDYPWLGVSFNLSSENTVKDSKLSNKLISSFSESNNNQTIVSTTEDHP
ISLGGSQREHTAVAYYLNAKLHLLDKKGIGDIAPGKTVRLGLLKPSIDVRKGNTGLSGILSFNATWDIKDTGQIPVKLGL
QVKAGRCINKPNPNKNTKAPSPALTAPALWFGPRQDGKVQMYSASVSTYPDSSSSKIFLQNLSRNDDKNKPGRYSLKPLS
ENEIKSKEPRFNGRQTVIRLDSGVQLIKLNGSKDEVVIFGNNGNNGTFGIVKEANVNLEADEWKKVLLPWTVRGPDNDNK
FKLINQKPDRYSQRYRIRENGNRDLGDIVNSPIVAVGGYLATSANDGMVHIFKKTGTDERSYNLKLSYIPGTMERKDIEG
NDSDLAKELRTFAEKGYVGDRYGVDGGFVLRQVNLNGQDRVFMFGAMGLGGRGAYALDLSKINENYPAAAPLFDVKNGDK
NGKNGKNRVEVELGYTVGTPQIGKTRSGKYAAFLASGYAAKDIGSGDNKTALYVYDLNNTLGTPIAKIEVKDGKGGLSSP
TLVDKDLDGTVDIAYAGDRGGNMYRFDLSNSDPNKWSVRTIFEGTKPITSAPAVSRLKDKRVVIFGTGSDLTEDDVLDTK
EQYIYGIFDDDKAANNVNASRGVLGSGLLEQHLTQENKTLFLNKRSDGSGSKGWAVKLTGGRRVTVKPTVVLRTAFVTIR
KYKDDGCGAETAILGINTADGGALTPRSARPIVPEANTAVAQYSGHKKTAGGKSVPIGCMEKGGKTVCPNGYVYDKPVNV
RYLDETETDGFSTTADGDAGGSGIDPAGRRPGKNNRCFSKKGVRTLLMNDLDSLDITGPMCGIKRLSWREVFF

Nucleotide


Download         Length: 3102 bp        

>NTDB_id=385892 F0T12_RS00270 WP_164824758.1 53431..56532(-) (pilC) [Neisseria gonorrhoeae strain NG290]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATACCGCCATATTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGCAGGCGCAAGCCCGTGACTACGCTATTATCATGAACGGGCGAAACCAGCCCGAGGTAAAGTCGAATGTGC
CATCTTCAATAAAGGACAAAGACAGGAAGCGGACATTTAGCCATACGAGCCAGACAAACTGGCGGGGCCAACAAAACAAT
TTTATCTCATTCGACAATAGCGATGAGCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCC
GCCCTACGGCAAGGTTTCCGGTTTTGATACCGATAGGCTGAAAAAGCGCAACAATGCCGTTGATTGGATTCGTACCACCC
GCATCGCGCTGGCAGGCTACAGCTACGAAGGTGTCGTATGCAGAAGCGGCACAGGCTGTCCCAAACTTGTCTATAAAACC
CGATTTTCCTTCGATAATCCCGACTTGGTAAAAAATGCGGGCAAGCTGGATAGGTACACAGACCTAAGCCGCGAAAATTC
GCCCATTTACAAATTGAAGGATTATCCATGGTTGGGCGTATCTTTCAATTTGAGCAGCGAGAATACCGTCAAAGATAGCA
AATTATCCAACAAATTGATATCTTCTTTTAGTGAAAGCAATAATAATCAAACCATCGTCTCTACGACAGAAGACCACCCT
ATTTCCCTTGGCGGCTCGCAGCGCGAACATACCGCCGTGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGATAAAAA
AGGGATTGGAGATATCGCGCCAGGCAAAACAGTGCGGTTGGGTCTCTTGAAGCCGAGCATCGATGTGCGGAAAGGAAATA
CGGGGCTTAGCGGCATTCTATCTTTTAATGCTACGTGGGACATTAAAGATACCGGGCAGATTCCGGTCAAGCTCGGCCTG
CAAGTCAAAGCAGGCCGCTGCATCAATAAACCGAACCCCAATAAGAATACCAAAGCCCCTTCGCCGGCACTGACCGCCCC
CGCGCTGTGGTTCGGACCTAGGCAAGATGGTAAGGTGCAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGA
GCAGCAAAATTTTCCTGCAAAACCTTTCCCGCAATGATGACAAAAACAAACCGGGCCGCTATTCCCTCAAACCCTTGAGT
GAGAATGAGATTAAAAGTAAAGAGCCGCGTTTCAACGGAAGGCAGACCGTCATCCGATTGGATAGCGGCGTACAGCTGAT
CAAACTGAATGGAAGCAAGGATGAGGTCGTCATTTTTGGAAACAACGGCAACAACGGCACTTTCGGCATTGTTAAGGAAG
CGAACGTCAATCTTGAAGCCGACGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGGGGTCCCGATAATGACAATAAA
TTTAAATTAATTAACCAAAAACCAGACAGATACAGCCAAAGATACCGCATCCGCGAAAACGGCAATCGCGATTTGGGCGA
CATCGTCAACAGCCCGATTGTCGCGGTCGGCGGGTATCTGGCAACTTCTGCCAACGACGGGATGGTGCATATCTTCAAAA
AAACCGGCACGGATGAACGCAGCTACAATCTGAAGCTCAGCTACATCCCCGGTACGATGGAGCGTAAGGATATTGAAGGC
AATGACTCCGACCTCGCCAAAGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGG
CTTTGTCTTGCGTCAAGTTAACTTAAACGGACAAGACCGCGTGTTTATGTTCGGCGCAATGGGCCTTGGCGGCAGAGGCG
CATACGCCTTGGATTTAAGCAAAATCAACGAAAATTATCCGGCCGCCGCTCCCCTGTTTGATGTCAAAAATGGCGATAAA
AACGGCAAAAACGGCAAAAATCGCGTGGAAGTGGAATTAGGCTACACCGTCGGTACGCCGCAAATCGGCAAAACCCGCAG
CGGCAAATACGCCGCCTTCCTCGCTTCCGGTTATGCGGCTAAAGATATTGGCAGCGGCGATAATAAAACCGCGCTGTATG
TATATGATTTGAACAACACCTTAGGTACGCCGATTGCAAAAATCGAAGTGAAGGACGGCAAAGGCGGGCTTTCGTCCCCC
ACGCTGGTGGATAAAGATTTGGACGGCACGGTCGATATCGCCTATGCCGGCGACCGGGGCGGCAATATGTACCGCTTTGA
TTTGAGCAATTCCGATCCTAATAAATGGTCTGTAAGGACTATTTTCGAAGGCACAAAACCGATTACCTCCGCGCCCGCCG
TTTCCCGACTGAAAGACAAACGCGTCGTCATCTTCGGTACGGGCAGCGATTTGACCGAAGATGATGTACTCGATACGAAA
GAACAATATATTTACGGTATCTTTGACGACGATAAGGCGGCGAATAATGTAAATGCAAGCCGCGGCGTTTTGGGGAGCGG
GCTGCTCGAGCAACACCTTACTCAGGAAAATAAAACATTATTCCTGAACAAGAGATCCGACGGTTCGGGCAGCAAGGGCT
GGGCGGTGAAATTGACAGGCGGACGGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTCGTAACCATCCGC
AAATATAAAGACGACGGCTGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGCATTGACTCCGAG
AAGCGCGCGCCCGATTGTGCCGGAAGCCAATACGGCTGTCGCACAATATTCCGGCCATAAGAAAACCGCCGGCGGCAAGT
CCGTCCCTATAGGTTGTATGGAAAAAGGCGGTAAAACCGTCTGCCCGAACGGATATGTTTACGACAAGCCGGTTAATGTG
CGTTATCTGGATGAAACGGAAACAGACGGATTTTCAACGACGGCGGACGGCGATGCGGGCGGCAGCGGTATAGACCCCGC
CGGCAGGCGTCCCGGCAAAAACAACCGCTGCTTCTCCAAAAAAGGTGTGCGCACCCTGCTGATGAACGATTTGGACAGCT
TGGATATTACCGGCCCGATGTGCGGTATCAAACGCTTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(505-843)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

72.96

100

0.744

Multiple sequence alignment