Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HPSJM_RS04010 Genome accession   NC_014560
Coordinates   844027..845811 (+) Length   594 a.a.
NCBI ID   WP_000774393.1    Uniprot ID   -
Organism   Helicobacter pylori SJM180     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 839027..850811
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPSJM_RS03980 (HPSJM_04135) motB 839746..840519 (+) 774 WP_001085324.1 flagellar motor protein MotB -
  HPSJM_RS03985 (HPSJM_04140) - 840516..840962 (+) 447 WP_001081239.1 hypothetical protein -
  HPSJM_RS03990 (HPSJM_04145) - 841076..842737 (+) 1662 WP_000901300.1 glycine betaine ABC transporter substrate-binding protein -
  HPSJM_RS03995 (HPSJM_04150) - 842741..843391 (+) 651 WP_000659333.1 ATP-binding cassette domain-containing protein -
  HPSJM_RS04000 - 843394..843573 (-) 180 WP_000468798.1 hypothetical protein -
  HPSJM_RS04005 (HPSJM_04155) - 843565..844026 (+) 462 WP_000437142.1 hypothetical protein -
  HPSJM_RS04010 (HPSJM_04160) uvrC 844027..845811 (+) 1785 WP_000774393.1 excinuclease ABC subunit UvrC Machinery gene
  HPSJM_RS04015 (HPSJM_04165) - 845822..847087 (+) 1266 WP_000746749.1 homoserine dehydrogenase -
  HPSJM_RS04020 (HPSJM_04170) - 847087..847431 (+) 345 WP_001211687.1 YraN family protein -
  HPSJM_RS04025 (HPSJM_04175) trxA 847520..847840 (+) 321 WP_000020199.1 thioredoxin -
  HPSJM_RS04030 (HPSJM_04180) trxB 847846..848781 (+) 936 WP_000564365.1 thioredoxin-disulfide reductase -
  HPSJM_RS04035 (HPSJM_04195) - 849139..849960 (+) 822 WP_001217896.1 glycosyltransferase family 25 protein -
  HPSJM_RS04040 (HPSJM_04200) - 850176..850424 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68601.81 Da        Isoelectric Point: 9.7562

>NTDB_id=38586 HPSJM_RS04010 WP_000774393.1 844027..845811(+) (uvrC) [Helicobacter pylori SJM180]
MADLLSSLKNLSNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNSRVSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDRLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLIPEQILLN
ACSNEALKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFNLECVPYRVEIFDV
SHHSNSQCVGGMVVYENHAFQKNSYRRYHLKGSNEYAQMSELLTRRALDFAKEPPPNLWVIDGGRVQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGTKDIIHTPSNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNIKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRN

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=38586 HPSJM_RS04010 WP_000774393.1 844027..845811(+) (uvrC) [Helicobacter pylori SJM180]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTAATAGCAGTGGGGTGTATCAATATTTTGATAAAAACCGCCAACT
GCTCTATATCGGTAAGGCAAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCCATCCGTAATAATGAAATCACGCCTA
ATTCTCGCGTAAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAACTCTTTAATCAAACAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCCTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAGTTGCTCCCTTTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCTCTGATTTACAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCCTTCACTTGCATGGATTTGGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGTGCAAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCCTTAATGGGTTTGACA
CTGATGAGGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATACCAGAACAGATTTTATTGAAC
GCTTGCTCTAACGAAGCGCTTAAAGAATTGCAAGAATTTATCTCTCATCAATATTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAGGGCGATAAGCTCGCTTTAATAGAGATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAATTTAGAGTGCGTGCCTTATAGGGTGGAAATCTTTGATGTA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGCATTCCAAAAAAACTCTTACCGGCG
CTACCATTTAAAAGGCTCTAACGAATACGCTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCTAAAGAGC
CACCGCCTAATTTATGGGTAATAGATGGAGGGAGGGTGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAGGCTTATCGTTCTAAAGGGGGCACTAAAGACATTAT
CCATACGCCTAGCAACACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAATGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATAAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAACAAGAAAAAAA
CGCCGTTTTGAAAAAACGAAATTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.965

99.832

0.968

Multiple sequence alignment