Detailed information    

insolico Bioinformatically predicted

Overview

Name   luxS   Type   Regulator
Locus tag   HHM36_RS06975 Genome accession   NZ_CP051615
Coordinates   1456462..1456977 (-) Length   171 a.a.
NCBI ID   WP_001130208.1    Uniprot ID   Q8FEP8
Organism   Escherichia coli O25b:H4-ST131 strain 2017_APHA     
Function   induction of competence (predicted from homology)   
Competence regulation

Genomic Context

Location: 1451462..1461977
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HHM36_RS06955 (HHM36_06955) emrA 1451610..1452782 (+) 1173 WP_001295175.1 multidrug efflux MFS transporter periplasmic adaptor subunit EmrA -
  HHM36_RS06960 (HHM36_06960) emrB 1452799..1454337 (+) 1539 WP_001296316.1 multidrug efflux MFS transporter permease subunit EmrB -
  HHM36_RS06965 (HHM36_06965) - 1454595..1455302 (+) 708 WP_001097132.1 RNA ligase family protein -
  HHM36_RS06970 (HHM36_06970) - 1455299..1456411 (+) 1113 WP_000638136.1 ATP-binding protein -
  HHM36_RS06975 (HHM36_06975) luxS 1456462..1456977 (-) 516 WP_001130208.1 S-ribosylhomocysteine lyase Regulator
  HHM36_RS06980 (HHM36_06980) gshA 1457127..1458683 (-) 1557 WP_000611804.1 glutamate--cysteine ligase -
  HHM36_RS06985 (HHM36_06985) yqaA 1458756..1459184 (-) 429 WP_001287462.1 YqaA family protein -
  HHM36_RS06990 (HHM36_06990) yqaB 1459181..1459747 (-) 567 WP_000273309.1 fructose-1-phosphate/6-phosphogluconate phosphatase -
  HHM36_RS07015 (HHM36_07015) csrA 1460796..1460981 (-) 186 WP_000906486.1 carbon storage regulator CsrA -

Sequence

Protein


Download         Length: 171 a.a.        Molecular weight: 19443.21 Da        Isoelectric Point: 5.0362

>NTDB_id=385698 HHM36_RS06975 WP_001130208.1 1456462..1456977(-) (luxS) [Escherichia coli O25b:H4-ST131 strain 2017_APHA]
MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISP
MGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARNILERDVRINSNEELA
LPKEKLQELHI

Nucleotide


Download         Length: 516 bp        

>NTDB_id=385698 HHM36_RS06975 WP_001130208.1 1456462..1456977(-) (luxS) [Escherichia coli O25b:H4-ST131 strain 2017_APHA]
ATGCCGTTGTTAGATAGCTTCACAGTCGATCATACCCGGATGGAAGCGCCTGCAGTTCGGGTGGCGAAAACAATGAACAC
CCCGCATGGCGACGCAATCACCGTGTTCGATCTGCGCTTCTGCGTGCCGAACAAAGAAGTGATGCCAGAAAGAGGGATCC
ATACCCTGGAGCACCTGTTTGCTGGTTTTATGCGTAACCATCTTAACGGTAATGGCGTAGAGATTATCGATATCTCGCCA
ATGGGCTGCCGCACCGGTTTTTATATGAGTCTGATTGGTACGCCAGATGAGCAGCGTGTCGCTGATGCCTGGAAAGCGGC
AATGGAAGACGTGCTGAAAGTGCAGGATCAGAATCAGATCCCGGAACTGAACGTCTACCAGTGTGGCACTTACCAGATGC
ACTCGTTGCAGGAAGCGCAGGATATTGCGCGTAACATTCTGGAACGTGACGTGCGCATCAACAGCAACGAAGAACTGGCG
CTGCCGAAAGAGAAGTTGCAGGAACTGCACATTTAG

Domains

Predicted by InterProScan.

S-Ribosylhomocysteinase (LuxS) (LuxS)

(4-152)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8FEP8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  luxS Vibrio cholerae strain A1552

73.684

100

0.737