Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HPPC_RS03975 Genome accession   NC_014555
Coordinates   834658..836442 (+) Length   594 a.a.
NCBI ID   WP_000774346.1    Uniprot ID   -
Organism   Helicobacter pylori PeCan4     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 829658..841442
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPPC_RS08595 (HPPC_04135) - 830173..831597 (-) 1425 WP_000855859.1 DNA methyltransferase -
  HPPC_RS03955 (HPPC_04140) - 831709..833370 (+) 1662 WP_001139203.1 ABC transporter permease/substrate-binding protein -
  HPPC_RS03960 (HPPC_04145) - 833372..834022 (+) 651 WP_000665998.1 ATP-binding cassette domain-containing protein -
  HPPC_RS03965 - 834025..834204 (-) 180 WP_000468798.1 hypothetical protein -
  HPPC_RS03970 (HPPC_04150) - 834196..834657 (+) 462 WP_000437161.1 hypothetical protein -
  HPPC_RS03975 (HPPC_04155) uvrC 834658..836442 (+) 1785 WP_000774346.1 excinuclease ABC subunit UvrC Machinery gene
  HPPC_RS03980 (HPPC_04160) - 836452..837717 (+) 1266 WP_000746846.1 homoserine dehydrogenase -
  HPPC_RS03985 (HPPC_04165) - 837718..838062 (+) 345 WP_001211718.1 YraN family protein -
  HPPC_RS03990 (HPPC_04170) trxA 838151..838471 (+) 321 WP_000020199.1 thioredoxin -
  HPPC_RS03995 (HPPC_04175) trxB 838477..839412 (+) 936 WP_000564369.1 thioredoxin-disulfide reductase -
  HPPC_RS04000 (HPPC_04180) - 839579..840400 (+) 822 WP_001263411.1 glycosyltransferase family 25 protein -
  HPPC_RS04005 (HPPC_04185) - 840621..840869 (-) 249 WP_000790555.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68978.36 Da        Isoelectric Point: 9.8121

>NTDB_id=38566 HPPC_RS03975 WP_000774346.1 834658..836442(+) (uvrC) [Helicobacter pylori PeCan4]
MADLLSSLKNLSHSSGVYQYFDKNHQLLYIGKAKNLKKRIKSYFSVRNNEITPNYRTSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGRGHKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
ACSNEVLKELQEFISHRYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRVQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSNTFKLFPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLRKRK

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=38566 HPPC_RS03975 WP_000774346.1 834658..836442(+) (uvrC) [Helicobacter pylori PeCan4]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGACAAAAACCACCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTGTCCGTAATAATGAAATCACGCCCA
ATTATCGCACAAGCTTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAACAA
GACGCTTTGATCTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCAGGGGCCATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAACGGGTTTGACA
CCGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCTGAACAGATCTTATTGAGC
GCTTGCTCCAATGAAGTGCTTAAAGAATTGCAAGAATTTATCTCTCACCGATACTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAGGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCCAAAGAGC
CGCCACCTAATTTGTGGGTGATTGATGGAGGGAGGGTGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGTGCTAAAGACATTAT
CCATACGCCTAGCAATACTTTTAAATTATTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAGAAAACGAAAATAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.121

99.832

0.96

Multiple sequence alignment