Detailed information NTG0385635

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: HHM37_RS11960
• Genome accession: NZ_CP051609
• Coordinates: 2494515..2495498 (-)
• Length: 327 a.a.
• NCBI ID: WP_001196477.1
• Uniprot ID: A0A0H2VBW7
• Organism: Escherichia coli O25b:H4-ST131 strain 2019_APHA
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 2489515..2500498

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HHM37_RS11935 (HHM37_11930)	-	2490664..2490771 (-)	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
HHM37_RS11940 (HHM37_11935)	-	2491147..2491254 (-)	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
HHM37_RS11945 (HHM37_11940)	-	2491630..2491737 (-)	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
HHM37_RS11950 (HHM37_11945)	yhjV	2492213..2493484 (+)	1272	WP_001296513.1	aromatic amino acid transport family protein	-
HHM37_RS11955 (HHM37_11950)	dppF	2493514..2494518 (-)	1005	WP_000103571.1	dipeptide ABC transporter ATP-binding subunit DppF	-
HHM37_RS11960 (HHM37_11955)	amiE	2494515..2495498 (-)	984	WP_001196477.1	dipeptide ABC transporter ATP-binding protein	Regulator
HHM37_RS11965 (HHM37_11960)	dppC	2495509..2496411 (-)	903	WP_000084677.1	dipeptide ABC transporter permease DppC	-
HHM37_RS11970 (HHM37_11965)	dppB	2496421..2497440 (-)	1020	WP_000938855.1	dipeptide ABC transporter permease DppB	-
HHM37_RS11975 (HHM37_11970)	dppA	2497747..2499354 (-)	1608	WP_001222871.1	dipeptide ABC transporter substrate-binding protein DppA	-

Sequence

Protein

• Length: 327 a.a.
• Molecular weight: 35801.38 Da
• Isoelectric Point: 6.5813

>NTDB_id=385635 HHM37_RS11960 WP_001196477.1 2494515..2495498(-) (amiE) [Escherichia coli O25b:H4-ST131 strain 2019_APHA]
MALLNVDKLSVHFGDESAPFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDYPGRVMAEKLEFNGQDLQRISE
KERRNLVGAEVAMIFQDPMTSLNPCYTVGFQIMEAIKVHQGGNKSTRRQRAIDLLNLVGIPDPASRLDVYPHQLSGGMSQ
RVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGDAHA
IFHAPRHPYTQALLRALPEFAQDKERLASLPGVVPGKYDRPNGCLLNPRCPYATDKCRAEEPALNMLADGRQSKCHYPLD
DAGRPTL

Nucleotide

• Length: 984 bp

>NTDB_id=385635 HHM37_RS11960 WP_001196477.1 2494515..2495498(-) (amiE) [Escherichia coli O25b:H4-ST131 strain 2019_APHA]
ATGGCGTTATTAAATGTAGATAAATTATCGGTGCATTTCGGCGACGAAAGCGCACCGTTCCGCGCTGTAGACCGCATCAG
CTACAGCGTAAAACAGGGTGAAGTGGTCGGGATTGTGGGTGAGTCCGGCTCTGGTAAATCGGTCAGTTCGCTGGCGATTA
TGGGGCTGATTGATTATCCGGGCCGCGTAATGGCGGAAAAGCTGGAGTTTAACGGTCAGGATTTGCAGCGTATCTCAGAA
AAAGAGCGCCGCAACCTGGTGGGTGCCGAAGTGGCAATGATCTTCCAGGACCCGATGACCAGCCTTAACCCGTGCTACAC
CGTGGGTTTCCAGATTATGGAAGCGATTAAGGTGCATCAAGGCGGCAACAAAAGTACCCGCCGTCAGCGAGCGATTGACC
TGCTGAATCTGGTCGGTATTCCCGATCCGGCATCGCGTCTGGATGTTTACCCGCATCAGCTTTCCGGCGGCATGAGCCAG
CGCGTGATGATCGCCATGGCGATTGCCTGTCGGCCAAAACTGCTGATTGCCGATGAACCAACCACTGCGCTGGACGTGAC
CATTCAGGCGCAAATTATCGAACTGCTGCTGGAGCTACAGCAGAAAGAGAACATGGCGCTGGTGTTAATTACCCATGACC
TGGCGCTGGTGGCGGAAGCGGCACATAAAATTATCGTGATGTATGCAGGCCAGGTAGTAGAAACGGGCGATGCGCACGCT
ATCTTCCATGCGCCGCGTCACCCGTATACTCAGGCATTGCTGCGTGCGCTGCCGGAATTTGCTCAGGACAAAGAACGTCT
GGCGTCGTTGCCAGGTGTCGTTCCCGGCAAGTACGACCGCCCGAACGGCTGCCTGCTTAACCCGCGCTGCCCCTACGCCA
CTGACAAATGCCGTGCTGAAGAACCGGCGCTGAATATGCTCGCTGACGGGCGTCAGTCCAAATGCCATTACCCACTTGAT
GATGCCGGGAGGCCGACACTATGA

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (24-181)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (233-297)

3D structure

• AlphaFold DB: A0A0H2VBW7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	43.302	98.165	0.425
amiE	Streptococcus thermophilus LMG 18311	42.991	98.165	0.422
amiE	Streptococcus thermophilus LMD-9	42.991	98.165	0.422
oppD	Streptococcus mutans UA159	41.379	97.554	0.404