Detailed information NTG0385513

Bioinformatically predicted

Overview

• Name: uvrC
• Type: Machinery gene
• Locus tag: FJR48_RS09120
• Genome accession: NZ_CP043617
• Coordinates: 1816149..1817948 (+)
• Length: 599 a.a.
• NCBI ID: WP_152307827.1
• Uniprot ID: A0A5P8P2E8
• Organism: Sulfurimonas lithotrophica strain GYSZ_1
• Function: integration of short DNA fragment (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1811149..1822948

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FJR48_RS09105 (FJR48_09105)	nhaD	1812760..1814142 (-)	1383	WP_152307824.1	sodium:proton antiporter NhaD	-
FJR48_RS09110 (FJR48_09110)	nadB	1814142..1815599 (-)	1458	WP_152307825.1	L-aspartate oxidase	-
FJR48_RS09115 (FJR48_09115)	-	1815719..1816162 (+)	444	WP_152307826.1	hypothetical protein	-
FJR48_RS09120 (FJR48_09120)	uvrC	1816149..1817948 (+)	1800	WP_152307827.1	excinuclease ABC subunit UvrC	Machinery gene
FJR48_RS09125 (FJR48_09125)	-	1818021..1818434 (+)	414	WP_152307828.1	PAS domain-containing protein	-
FJR48_RS12345	-	1818453..1820192 (+)	1740	WP_241856047.1	hypothetical protein	-

Sequence

Protein

• Length: 599 a.a.
• Molecular weight: 69667.69 Da
• Isoelectric Point: 9.2439

>NTDB_id=385513 FJR48_RS09120 WP_152307827.1 1816149..1817948(+) (uvrC) [Sulfurimonas lithotrophica strain GYSZ_1]
MTLTETIQQLPASAGIYQYFDKDGHLLYVGKAKNLKNRVKSYFSFTPTLRPSPNLSYRIKSMIEQTITLNYIVVNTEHDA
LILENSLIKQLNPKYNILLRDDKTYPYIYIDYAQEYPRFDITRKIIDAKDITYFGPYSIGARDILNSIYELCKLVQKKGC
LKSKKLCLYYQIDKCLGPCEKEIPNELYQKEIDKAIKLIKSKSKLTRELMKKMEFYAEELRFEEAAELRDRCERISRSEI
KSDIDFASSENFDIFAVEHNEKRLVILKIFMRNGKIISSSHSITTLNNGFDKEEIFHRLLIEFYQQKPPIIAPILLQESF
DEIDSVEEYLSDIFDKKAQIIIPQRGKKKQLIDLALINAKELLKNDKKTIDFKVENQLLELLKLEKFPQRVECFDNSHMA
GMATVGAMIVYDNAKFDKKSYRTYHLDAKDEYSQMRETLTRRINSFEKNSPPDLWVLDGGATLLKLALDILESSGVNIDV
IAISKEKVDEKAHRAKGSAKDIIYTKDEVFRLKTSDKRLQWVQNLRDEAHRCAIGFHKKTKLKLDQESKLLNLNGISHAK
VKKLLNHFGTFEHIKTLSIEEISTVLNKKDANIIKNLYK

Nucleotide

• Length: 1800 bp

>NTDB_id=385513 FJR48_RS09120 WP_152307827.1 1816149..1817948(+) (uvrC) [Sulfurimonas lithotrophica strain GYSZ_1]
ATGACATTAACTGAAACCATTCAGCAACTGCCTGCTTCTGCCGGTATATATCAATATTTTGACAAAGACGGGCATCTGCT
ATATGTCGGAAAAGCAAAAAACTTAAAAAACCGTGTAAAGAGTTACTTTAGTTTTACCCCTACATTAAGACCTAGTCCAA
ACCTTTCGTACAGAATAAAAAGTATGATTGAACAAACGATAACTTTAAACTATATAGTAGTAAATACCGAACACGATGCT
TTGATTTTAGAAAATTCTCTAATCAAACAACTCAATCCAAAATATAATATATTACTTCGAGATGATAAAACATACCCATA
TATCTACATTGACTACGCACAAGAGTATCCGAGATTCGATATAACCAGAAAAATCATAGATGCAAAAGATATAACATACT
TTGGACCTTATTCTATAGGTGCTAGAGATATCTTAAACTCAATATATGAACTTTGTAAACTTGTTCAAAAAAAAGGTTGT
TTAAAATCAAAAAAACTCTGCTTGTACTATCAAATAGACAAGTGCCTTGGTCCGTGTGAAAAAGAGATACCAAACGAGTT
GTATCAAAAAGAGATAGACAAAGCTATAAAACTTATAAAAAGCAAATCTAAACTAACTCGTGAACTTATGAAAAAAATGG
AGTTTTACGCGGAGGAATTAAGGTTTGAAGAAGCAGCAGAGCTTAGGGACAGGTGTGAAAGAATTTCAAGAAGTGAAATA
AAAAGCGATATTGATTTTGCATCAAGTGAGAACTTCGACATTTTTGCGGTTGAACATAATGAAAAAAGACTCGTCATACT
TAAAATTTTTATGAGAAACGGGAAGATAATCTCATCTTCGCACAGCATAACTACTCTAAATAACGGTTTTGACAAAGAGG
AAATTTTTCACAGACTTTTAATAGAGTTTTATCAACAAAAGCCACCTATCATTGCTCCTATTTTATTACAAGAAAGTTTT
GATGAGATTGACAGTGTTGAAGAGTATCTAAGCGATATATTTGATAAAAAAGCTCAAATAATAATCCCTCAAAGAGGTAA
GAAAAAACAACTCATAGATTTAGCATTGATAAATGCCAAAGAACTACTGAAAAATGACAAAAAAACTATAGATTTTAAAG
TAGAAAACCAACTGCTTGAACTTCTTAAACTAGAAAAATTTCCGCAAAGAGTGGAATGTTTTGACAACTCCCATATGGCA
GGTATGGCAACTGTAGGTGCTATGATAGTCTATGACAATGCCAAGTTTGATAAAAAATCTTACAGGACCTATCATCTGGA
TGCAAAAGACGAATATTCCCAAATGAGAGAGACTTTAACACGTCGTATAAATAGTTTTGAAAAAAACTCGCCTCCTGATT
TATGGGTATTAGACGGTGGAGCTACTTTGCTAAAACTGGCTTTGGATATACTTGAATCATCAGGTGTAAATATCGACGTA
ATAGCTATTTCTAAAGAAAAAGTCGATGAAAAAGCACACCGTGCAAAAGGCTCGGCAAAAGATATAATCTATACAAAAGA
TGAAGTTTTTAGACTCAAAACAAGTGATAAAAGACTACAATGGGTACAAAACTTGAGAGATGAAGCACACAGATGTGCTA
TAGGTTTTCATAAGAAAACAAAATTAAAGCTTGATCAAGAGAGTAAACTTTTAAATTTAAACGGAATTTCTCATGCAAAA
GTTAAAAAACTATTGAATCACTTTGGTACTTTTGAACATATTAAAACATTATCCATTGAAGAGATAAGCACTGTTTTAAA
TAAAAAAGATGCAAATATAATCAAAAATCTCTATAAATAA

Domains

Predicted by InterproScan.

• UvrB/uvrC motif (UVR) (204-236)

• GIY-YIG catalytic domain (GIY-YIG) (15-96)

• UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom) (380-534)

3D structure

• AlphaFold DB: A0A5P8P2E8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrC	Helicobacter pylori 26695	49.153	98.497	0.484