Detailed information NTG0385204

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: HG583_RS07205
• Genome accession: NZ_CP051533
• Coordinates: 1515006..1517522 (+)
• Length: 838 a.a.
• NCBI ID: WP_202142843.1
• Uniprot ID: -
• Organism: Helicobacter pylori strain LIM-010
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1510006..1522522

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HG583_RS07165 (HG583_07140)	-	1510214..1512025 (+)	1812	WP_202142841.1	DUF262 domain-containing protein	-
HG583_RS07170 (HG583_07145)	-	1512175..1512621 (+)	447	Protein_1405	hypothetical protein	-
HG583_RS07175 (HG583_07150)	-	1512707..1513495 (+)	789	WP_202142842.1	integrase	-
HG583_RS07180 (HG583_07155)	-	1513516..1513722 (+)	207	WP_237389105.1	hypothetical protein	-
HG583_RS07185 (HG583_07160)	-	1513719..1514198 (+)	480	WP_202138298.1	hypothetical protein	-
HG583_RS07190 (HG583_07165)	comB2	1514195..1514485 (+)	291	WP_021176075.1	TrbC/VirB2 family protein	Machinery gene
HG583_RS07195 (HG583_07170)	comB3	1514495..1514758 (+)	264	WP_001177721.1	hypothetical protein	Machinery gene
HG583_RS07200 (HG583_07175)	-	1514770..1515006 (+)	237	WP_128043359.1	hypothetical protein	-
HG583_RS07205 (HG583_07180)	comB4	1515006..1517522 (+)	2517	WP_202142843.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
HG583_RS08445	-	1517519..1517659 (+)	141	WP_000789926.1	hypothetical protein	-
HG583_RS07210 (HG583_07185)	-	1517652..1517996 (+)	345	Protein_1414	hypothetical protein	-
HG583_RS07215 (HG583_07190)	tnpA	1518166..1518633 (+)	468	WP_000063685.1	IS200/IS605 family transposase	-
HG583_RS07220 (HG583_07195)	-	1518602..1519750 (+)	1149	WP_202142844.1	RNA-guided endonuclease TnpB family protein	-
HG583_RS07225 (HG583_07200)	-	1519840..1520094 (+)	255	WP_202142845.1	hypothetical protein	-
HG583_RS07230 (HG583_07205)	-	1520096..1520293 (+)	198	WP_202142846.1	hypothetical protein	-

Sequence

Protein

• Length: 838 a.a.
• Molecular weight: 96470.47 Da
• Isoelectric Point: 8.8778

>NTDB_id=385204 HG583_RS07205 WP_202142843.1 1515006..1517522(+) (comB4) [Helicobacter pylori strain LIM-010]
MLENAFKYCKEKAIELLTGFVPKTYSMAEECNILGLYDDTFIITKQENLVAIMSLQGLSYSNLMQKDLEGYFDTRQNVLN
TISKDIQLRIVAKRRKESINQSPNIDNPYAKAIITQFESKEIYKTEYFLVFESITSNVKSFFEKKKLEMTTSINEELEES
SKKDKKNKFKKKTTFSATSKRALLIQTIERVKNALREFKPTLLNSKEVLNFYAEYINGKYIAFNPKLKRLSDSYIASNVH
FKKDYFVIEFQNQSTFCACVGIKNYESEEISSLPISTLLHTQIELDLIFHIRSLGQFESLNFLKTKKKLTLSKMVKNDID
DYIELVQANRLSMQECALNLVIRAKSKAKLDKSLKEILSLLNNAGLGSVTETIGLKPSYFSFFPNNANINPRMRNQTSQV
IASLILFEKNNTGFRANSWGDMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGHTMIIGATGAGKTTLISYLMM
SALKYSNIDILALDRLNGLYSFTKYFDGIYNQGENFHINPFSLEDSATNRAFLLHFYAQMAKVDSYDDHKDKVEDRTALL
NAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNAIVKTNTDILDSSFEDYLKSSLFSSRMDSLDFKTRISTINTDSIL
HNDDDAGLLAYYVFHKMIDRALKINRGFLCFIDEFKSYAQNEMMNKKINEIITQARKANGVIVLALQDINQLTEVRNAQS
FIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNIIDVSLSSLGNYLQIFSSNSSM
VEHIDNLIKHYPKTWREVFVSNKHENFDDKKHLEKVLK

Nucleotide

• Length: 2517 bp

>NTDB_id=385204 HG583_RS07205 WP_202142843.1 1515006..1517522(+) (comB4) [Helicobacter pylori strain LIM-010]
ATGCTAGAAAACGCTTTTAAATATTGCAAAGAGAAAGCCATAGAGCTTTTAACAGGTTTTGTGCCAAAAACCTATTCTAT
GGCAGAGGAATGCAATATTTTAGGCTTGTATGATGATACTTTTATTATCACCAAACAAGAAAATTTAGTCGCTATTATGT
CTTTACAAGGACTAAGTTATTCTAATTTAATGCAAAAAGATTTGGAGGGCTATTTTGATACAAGACAAAATGTTCTCAAT
ACCATTAGTAAGGACATTCAATTAAGGATTGTGGCTAAAAGGCGTAAAGAATCTATCAATCAAAGCCCCAACATTGACAA
CCCTTATGCCAAAGCCATTATCACACAATTTGAAAGCAAGGAAATCTATAAAACAGAATATTTTTTAGTGTTTGAGAGCA
TTACTTCTAATGTCAAATCTTTCTTTGAGAAAAAGAAATTAGAAATGACTACTTCAATCAATGAAGAATTAGAAGAAAGC
TCTAAAAAAGACAAGAAAAACAAGTTCAAAAAAAAGACAACCTTTAGCGCCACAAGTAAAAGAGCCTTACTCATTCAAAC
CATAGAAAGAGTGAAAAACGCATTAAGAGAGTTTAAACCCACTCTCTTAAATTCTAAAGAAGTGTTGAATTTCTATGCGG
AGTATATCAATGGCAAATACATCGCCTTTAATCCTAAGTTAAAGCGACTAAGCGATAGCTATATTGCATCTAATGTGCAT
TTTAAAAAAGATTACTTTGTCATTGAATTTCAAAATCAAAGCACCTTTTGTGCGTGTGTGGGTATTAAAAACTATGAGAG
TGAAGAAATTTCTTCTCTCCCCATTTCTACCCTTTTACACACGCAAATTGAATTAGATTTAATCTTTCATATCCGTTCAT
TAGGGCAGTTTGAAAGCTTGAATTTTCTAAAAACCAAGAAAAAACTCACGCTTTCTAAAATGGTGAAAAATGATATTGAT
GATTATATAGAATTGGTGCAAGCCAATCGTTTGAGTATGCAAGAGTGTGCCTTAAACTTAGTTATAAGAGCTAAGAGCAA
AGCCAAATTAGACAAATCTTTAAAAGAGATTTTATCCTTGCTTAATAACGCTGGACTAGGCAGTGTTACAGAAACCATAG
GGCTAAAACCCTCTTATTTTTCATTCTTCCCTAATAATGCAAACATTAACCCTAGAATGAGAAATCAAACTTCCCAAGTG
ATAGCCTCTTTAATCTTGTTTGAAAAAAATAATACAGGTTTTAGGGCAAATTCTTGGGGTGATATGCCTCTATCTGTGTT
TAAGAACCTAGACCATAGCCCTTATTTGTTTAACTTCCACAACCAAGAAGTCAAACATAAAGGCGTGTTAGCCCATAATG
TTGCACGAGTGGTAGGGCATACGATGATTATAGGAGCAACAGGAGCTGGTAAAACCACGCTCATTAGCTATTTAATGATG
AGCGCTTTAAAATACTCTAACATTGATATTCTAGCTCTTGATAGATTAAATGGTTTGTATTCTTTTACCAAGTATTTTGA
TGGGATTTATAATCAAGGCGAAAACTTTCATATTAACCCTTTTTCATTAGAAGATAGCGCAACTAATAGAGCCTTTTTAT
TGCATTTTTATGCCCAAATGGCAAAAGTGGATAGTTATGATGATCATAAGGATAAAGTAGAAGATAGAACAGCCCTTTTA
AATGCTATTGATACGATGTATAGAAATTATAACGATGAAGTCAAACAAGCCAAATTTAGCAACCAAGAATTACCCCTTCC
TTTTGATTTAAAAGAGTTTGTCAATGCCATTGTTAAAACCAATACAGACATTTTAGATAGTAGTTTTGAAGACTATTTAA
AATCTTCCTTATTTTCTAGCCGAATGGATAGTCTAGATTTTAAAACTCGTATTAGCACCATAAATACCGATAGCATTTTA
CATAATGATGATGACGCTGGGCTTTTAGCCTACTATGTGTTTCATAAGATGATTGATAGAGCCTTGAAAATCAATCGTGG
TTTTTTATGCTTTATTGATGAGTTTAAATCTTACGCTCAAAATGAAATGATGAATAAAAAAATCAATGAAATCATTACCC
AAGCCAGAAAGGCTAATGGGGTGATTGTTCTAGCCTTACAAGACATTAACCAGCTAACTGAAGTTAGAAACGCTCAAAGC
TTTATTAAAAATATGGGGCAGTTGATTTTGTATCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCAT
TAGACTGAGCGATACTGAAAAGCATTTTTTAGAAAACACCGCCGTTAATGAATACAAAGTCTTACTCAAAAACATGAATG
ATGGCTCATCTAACATTATAGATGTGAGCCTAAGTTCTTTGGGTAATTACCTACAAATCTTTAGCTCTAATTCTAGCATG
GTAGAACACATTGATAATCTCATTAAGCATTACCCTAAAACTTGGCGAGAAGTCTTTGTGAGTAACAAACACGAAAATTT
TGATGACAAAAAACACTTAGAAAAGGTGCTTAAATGA

Domains

Predicted by InterProScan.

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (194-392)

• FtsK/SpoIIIE family (FtsK_SpoIIIE) (417-485)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	47.555	97.613	0.464