Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   F0M21_RS05890 Genome accession   NZ_CP043546
Coordinates   1125160..1125816 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain SYP-B637     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1120160..1130816
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F0M21_RS05865 (F0M21_05865) oppF 1120689..1121606 (+) 918 WP_012117283.1 oligopeptide ABC transporter ATP-binding protein OppF -
  F0M21_RS05870 (F0M21_05870) - 1121713..1122909 (+) 1197 WP_012117284.1 putative glycoside hydrolase -
  F0M21_RS05875 (F0M21_05875) - 1123018..1123596 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  F0M21_RS05880 (F0M21_05880) spx 1123775..1124170 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  F0M21_RS05885 (F0M21_05885) - 1124228..1124884 (-) 657 WP_012117285.1 TerC family protein -
  F0M21_RS19630 - 1125067..1125177 (+) 111 Protein_1091 adaptor protein MecA -
  F0M21_RS05890 (F0M21_05890) mecA 1125160..1125816 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  F0M21_RS05895 (F0M21_05895) - 1125967..1127127 (+) 1161 WP_012117286.1 competence protein CoiA family protein -
  F0M21_RS05900 (F0M21_05900) pepF 1127355..1129184 (+) 1830 WP_007409107.1 oligoendopeptidase F Regulator
  F0M21_RS19635 - 1129222..1129389 (-) 168 WP_003155026.1 hypothetical protein -
  F0M21_RS05905 (F0M21_05905) spxH 1129675..1130577 (-) 903 WP_012117287.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=384963 F0M21_RS05890 WP_003155032.1 1125160..1125816(+) (mecA) [Bacillus velezensis strain SYP-B637]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=384963 F0M21_RS05890 WP_003155032.1 1125160..1125816(+) (mecA) [Bacillus velezensis strain SYP-B637]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
GGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment