Detailed information    

insolico Bioinformatically predicted

Overview

Name   treR   Type   Regulator
Locus tag   MGAS2221_RS08815 Genome accession   NZ_CP043530
Coordinates   1751467..1752180 (+) Length   237 a.a.
NCBI ID   WP_002992823.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain MGAS2221     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1746467..1757180
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGAS2221_RS08805 (MGAS2221_1758) treC 1747537..1749165 (-) 1629 WP_010922745.1 alpha,alpha-phosphotrehalase -
  MGAS2221_RS08810 (MGAS2221_1759) treP 1749232..1751256 (-) 2025 WP_010922746.1 PTS system trehalose-specific EIIBC component -
  MGAS2221_RS08815 (MGAS2221_1760) treR 1751467..1752180 (+) 714 WP_002992823.1 trehalose operon repressor Regulator
  MGAS2221_RS08820 (MGAS2221_1761) - 1752459..1752725 (-) 267 WP_076640006.1 helix-turn-helix domain-containing protein -
  MGAS2221_RS08825 (MGAS2221_1762) - 1752984..1753841 (+) 858 WP_010922747.1 VOC family protein -
  MGAS2221_RS08830 (MGAS2221_1763) yaaA 1753883..1754614 (+) 732 WP_010922748.1 peroxide stress protein YaaA -
  MGAS2221_RS08835 (MGAS2221_1764) nrdG 1754788..1755402 (-) 615 WP_002982219.1 anaerobic ribonucleoside-triphosphate reductase activating protein -
  MGAS2221_RS08840 (MGAS2221_1765) - 1755402..1755911 (-) 510 WP_011285759.1 GNAT family N-acetyltransferase -
  MGAS2221_RS08845 (MGAS2221_1766) - 1755920..1756855 (-) 936 WP_010922750.1 Gfo/Idh/MocA family oxidoreductase -
  MGAS2221_RS08850 (MGAS2221_1767) - 1756884..1757030 (-) 147 WP_002982210.1 hypothetical protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27620.79 Da        Isoelectric Point: 9.6307

>NTDB_id=384867 MGAS2221_RS08815 WP_002992823.1 1751467..1752180(+) (treR) [Streptococcus pyogenes strain MGAS2221]
MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVRKALSLLTKAGLILKKQGRGTQVIRHHQIMFPISELT
SYQELVSYSNLDSKTNVIAIDKLIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTESRHKLEKFKFLDFARRRPK

Nucleotide


Download         Length: 714 bp        

>NTDB_id=384867 MGAS2221_RS08815 WP_002992823.1 1751467..1752180(+) (treR) [Streptococcus pyogenes strain MGAS2221]
ATGACAAAGTATGAACGTATTTATAAAGACCTCGAAACAAAAATAAACAAAGACTTTTACAAAGAAGGGGATTTTTTACC
TACTGAAATAGAATTGAGTCAACAATACCAAGCTAGCCGAGATACCGTCCGCAAGGCTCTCTCACTTCTCACAAAGGCAG
GTCTTATCCTCAAAAAACAAGGACGTGGCACCCAAGTGATTAGACATCATCAGATCATGTTCCCTATCTCAGAACTAACT
AGTTATCAGGAACTCGTCTCTTACTCAAATCTAGATTCTAAGACCAACGTCATTGCCATTGATAAACTGATTGTGGATGA
GACACTTTCAAAATTGACCGGTTTTAGCAAAAACAGCTTGGTCTGGCGTGTTACACGCCAACGCGTTGTTGAGGGTGTGG
CTTCCGTCTTAGACATTGATTACCTTAGTAAAACTTTGGTGCCAATAATGACAAGGGAAATCGCAGAGCATTCTATTTAT
CAATATTTGGAAAAGGAACTCCATCTCGCCATTGACTTTGCCCTCAAAGAGGTTACCATTGACCAAATAACCGATCGTGA
TAAAATTTTACTTGACCTTGGATCAGACCAACATGTTGTTTCCGTCAAATCCAAAGTCTACCTTTCCAATAATAACCAAT
TCCAATTCACCGAGAGTCGCCATAAACTGGAAAAATTTAAATTTTTAGATTTTGCTCGGCGCAGACCAAAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, gntR family (GntR)

(3-66)

UTRA domain (UTRA)

(91-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

68.376

98.734

0.675

Multiple sequence alignment