Detailed information    

insolico Bioinformatically predicted

Overview

Name   pptA   Type   Regulator
Locus tag   MGAS2221_RS07445 Genome accession   NZ_CP043530
Coordinates   1452075..1452800 (-) Length   241 a.a.
NCBI ID   WP_002983379.1    Uniprot ID   A0A4U7HHL6
Organism   Streptococcus pyogenes strain MGAS2221     
Function   export ComS (predicted from homology)   
Competence regulation

Genomic Context

Location: 1447075..1457800
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGAS2221_RS07410 (MGAS2221_1481) - 1447209..1447592 (+) 384 WP_002988673.1 ImmA/IrrE family metallo-endopeptidase -
  MGAS2221_RS07415 (MGAS2221_1482) - 1447603..1448154 (+) 552 WP_002988670.1 hypothetical protein -
  MGAS2221_RS07420 (MGAS2221_1483) - 1448271..1449350 (+) 1080 WP_002988667.1 tyrosine-type recombinase/integrase -
  MGAS2221_RS07430 (MGAS2221_1485) trmB 1449548..1450183 (-) 636 WP_002983387.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -
  MGAS2221_RS07435 (MGAS2221_1486) - 1450183..1450974 (-) 792 WP_002983385.1 phosphotransferase family protein -
  MGAS2221_RS07440 (MGAS2221_1487) - 1451038..1452072 (-) 1035 WP_010922583.1 ABC transporter permease -
  MGAS2221_RS07445 (MGAS2221_1488) pptA 1452075..1452800 (-) 726 WP_002983379.1 ABC transporter ATP-binding protein Regulator
  MGAS2221_RS07450 (MGAS2221_1489) - 1452872..1453291 (+) 420 WP_002983376.1 HIT family protein -
  MGAS2221_RS07455 (MGAS2221_1490) - 1453288..1453644 (+) 357 WP_002988657.1 hypothetical protein -
  MGAS2221_RS07460 (MGAS2221_1491) - 1453755..1455029 (-) 1275 WP_010922584.1 LCP family protein -
  MGAS2221_RS07465 (MGAS2221_1492) - 1455038..1455562 (-) 525 WP_009880752.1 N-acetyltransferase -
  MGAS2221_RS07470 (MGAS2221_1493) tsaE 1455537..1455998 (-) 462 WP_009880751.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  MGAS2221_RS07475 (MGAS2221_1494) - 1456152..1457612 (-) 1461 WP_011285677.1 NCS2 family permease -

Sequence

Protein


Download         Length: 241 a.a.        Molecular weight: 26678.75 Da        Isoelectric Point: 4.5624

>NTDB_id=384855 MGAS2221_RS07445 WP_002983379.1 1452075..1452800(-) (pptA) [Streptococcus pyogenes strain MGAS2221]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide


Download         Length: 726 bp        

>NTDB_id=384855 MGAS2221_RS07445 WP_002983379.1 1452075..1452800(-) (pptA) [Streptococcus pyogenes strain MGAS2221]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(17-160)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U7HHL6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pptA Streptococcus salivarius strain HSISS4

72.803

99.17

0.722
  pptA Streptococcus thermophilus LMD-9

71.967

99.17

0.714

Multiple sequence alignment