Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   CVCAS_RS08890 Genome accession   NC_017486
Coordinates   1825969..1828791 (-) Length   940 a.a.
NCBI ID   WP_003130311.1    Uniprot ID   Q9CEL9
Organism   Lactococcus lactis subsp. lactis CV56     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1820969..1833791
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CVCAS_RS08870 (CVCAS_1748) - 1821730..1823079 (-) 1350 WP_010906149.1 hemolysin family protein -
  CVCAS_RS08875 (CVCAS_1749) - 1823200..1824315 (-) 1116 WP_010906150.1 AI-2E family transporter -
  CVCAS_RS08880 (CVCAS_1750) - 1824464..1824907 (+) 444 WP_003130314.1 GNAT family N-acetyltransferase -
  CVCAS_RS08885 (CVCAS_1751) - 1824985..1825566 (-) 582 WP_003130313.1 uracil-DNA glycosylase family protein -
  CVCAS_RS13295 (CVCAS_1752) - 1825704..1825844 (+) 141 WP_003130312.1 hypothetical protein -
  CVCAS_RS08890 (CVCAS_1753) uvrA 1825969..1828791 (-) 2823 WP_003130311.1 excinuclease ABC subunit UvrA Machinery gene
  CVCAS_RS08895 (CVCAS_1754) - 1828870..1829508 (-) 639 WP_003130310.1 hypothetical protein -
  CVCAS_RS08900 (CVCAS_1755) - 1829577..1830101 (+) 525 WP_003130309.1 histidine phosphatase family protein -
  CVCAS_RS08905 (CVCAS_1756) - 1830098..1830412 (+) 315 WP_003130308.1 GIY-YIG nuclease family protein -
  CVCAS_RS08910 (CVCAS_1757) - 1830426..1831775 (-) 1350 WP_003130306.1 amino acid permease -
  CVCAS_RS08915 (CVCAS_1758) - 1832258..1833175 (-) 918 WP_003130304.1 Gfo/Idh/MocA family protein -

Sequence

Protein


Download         Length: 940 a.a.        Molecular weight: 104301.12 Da        Isoelectric Point: 6.4770

>NTDB_id=38481 CVCAS_RS08890 WP_003130311.1 1825969..1828791(-) (uvrA) [Lactococcus lactis subsp. lactis CV56]
MPQDKIVIHGAREHNLKNIDVEIPRDKLVVVTGVSGSGKSSLAFETLYAEGQRRYVESLSAYARQFLGNMDKPDVDSIDG
LSPAISIDQKTTSKNPRSTVGTVTEINDYLRLLYARVGTPYCVNGHGKISAQSVEEIVEQILELPEKTRLQILAPVVRTK
KGTHVKMFERIQKDGYVRVRVDGEVYDISEVPELDKNKKHNIEIVIDRIVVKEGIRSRLFDSVEAALHQAEGYVIVDKMD
GSELLFSEFYACPVCGFTVPELEPRLFSFNAPFGSCPDCDGLGVKLEPDVDLLIPDTSKTLREGAIIYWYGKASTYYPAL
LEQAMEQFGIDLDRPWEKLSEKEQQIVLYGNGDKLFHFLHEGDFGLRDQDMTFVGVIPNLWRRYRSGMSESAREMARSYM
TELTCTTCHGYRLNDQALSVKVGEKNIAEFSILSIGDTLDYVKSLVLSANNEIIAKPILKEIKDRLTFLKNVGLDYLTLS
RSSGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLIESLQKMRDLGNTLIVVEHDEDTMMAADWLIDVG
PGAGDLGGEIIASGTPKQVMKNKKSLTGQYLSGKRAIPVPEKRRAIDKKKMVKITGASENNLQNLDVEFPMGVMTAVTGV
SGSGKSTLVNSILKKSLAQKLNHNSEKPGKHKKITGYEGIERLIDIDQSPIGRTPRSNPATYTSVFDDIRDLFANTNEAK
IRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKGKNISEVLDMRVSDGLEFFRH
IPKIERKLQTIVDVGLGYVTLGQSATTLSGGEAQRMKLASELQKRSNGKAFYILDEPTTGLHSEDIATLIQVLDRLVEQG
NTIVVIEHNLDVIKTADYIIDLGPEGGAGGGTILAKGRPEEVAKVADSYTGQYLKAKLEK

Nucleotide


Download         Length: 2823 bp        

>NTDB_id=38481 CVCAS_RS08890 WP_003130311.1 1825969..1828791(-) (uvrA) [Lactococcus lactis subsp. lactis CV56]
ATGCCACAAGATAAAATAGTAATACATGGTGCACGTGAGCACAATTTAAAAAATATAGATGTTGAAATTCCAAGAGATAA
ATTAGTTGTTGTTACTGGGGTTTCAGGGTCTGGGAAATCATCTCTGGCCTTTGAAACTTTATATGCAGAAGGTCAACGTC
GATATGTTGAATCTTTGTCAGCTTATGCCAGACAGTTTTTAGGAAATATGGATAAACCAGATGTTGATTCAATTGATGGT
TTGTCGCCAGCAATCTCTATTGACCAAAAAACAACTTCTAAAAATCCTCGTTCAACAGTCGGGACGGTTACGGAAATTAA
TGACTATTTGCGTCTATTATACGCCCGTGTTGGGACGCCATATTGTGTGAATGGTCATGGAAAAATTTCGGCACAGTCAG
TTGAAGAAATTGTTGAACAAATTCTTGAACTCCCTGAAAAAACACGTTTACAAATTCTCGCTCCTGTCGTACGTACCAAA
AAAGGGACTCATGTTAAAATGTTTGAGCGTATCCAAAAAGATGGTTATGTTCGTGTTCGTGTTGATGGCGAAGTTTATGA
TATTTCAGAAGTTCCAGAACTTGATAAAAATAAAAAGCACAACATTGAAATTGTTATTGACCGGATTGTTGTAAAAGAAG
GAATTCGTTCGCGTCTTTTTGACTCTGTAGAGGCTGCGCTTCATCAGGCTGAGGGTTATGTTATTGTTGATAAAATGGAT
GGTTCAGAGCTTTTATTTAGTGAATTTTATGCCTGTCCAGTTTGTGGATTTACCGTTCCAGAACTTGAACCACGCCTTTT
CTCATTCAATGCTCCTTTTGGCTCATGCCCAGATTGTGATGGTTTAGGTGTTAAATTGGAACCCGATGTCGATTTATTGA
TTCCTGATACAAGCAAAACACTCCGTGAGGGAGCAATTATCTATTGGTATGGGAAAGCCTCAACTTATTACCCTGCTCTT
TTAGAGCAAGCAATGGAGCAATTCGGCATTGATTTAGATAGGCCTTGGGAAAAACTGTCAGAAAAAGAACAACAAATTGT
TTTATATGGAAATGGAGATAAACTTTTCCATTTTCTGCACGAAGGAGATTTTGGATTACGTGACCAAGATATGACCTTTG
TTGGGGTCATTCCTAATCTTTGGCGTCGTTATCGTTCAGGAATGAGCGAGTCAGCTAGAGAAATGGCGCGTTCTTACATG
ACTGAATTGACTTGTACGACTTGTCATGGTTATCGTTTAAATGATCAAGCACTTTCTGTTAAAGTGGGAGAGAAAAATAT
TGCTGAATTTTCAATTCTGTCAATTGGCGATACGCTTGATTATGTGAAAAGTTTAGTTCTTTCTGCAAATAATGAAATTA
TCGCAAAACCTATTTTGAAAGAAATTAAAGACCGTTTGACTTTCTTGAAAAATGTTGGTTTGGATTATCTTACGCTATCT
CGTTCAAGCGGAACACTCTCTGGTGGAGAGTCACAACGTATTCGTTTAGCGACACAGATTGGTTCAAATTTATCAGGCGT
TTTGTATATTTTGGATGAACCCTCCATTGGTTTACATCAAAGAGATAATGACAGACTGATTGAGTCTTTACAAAAGATGC
GTGATTTGGGGAATACCTTAATTGTCGTTGAACATGATGAGGACACGATGATGGCAGCCGATTGGCTTATTGATGTTGGG
CCTGGGGCAGGTGATTTAGGAGGTGAAATTATTGCCTCTGGAACACCAAAACAAGTCATGAAAAATAAAAAATCACTGAC
AGGGCAATATTTGTCAGGAAAAAGAGCCATTCCAGTTCCTGAAAAACGTCGAGCCATTGATAAGAAAAAAATGGTTAAGA
TTACAGGTGCAAGTGAGAACAACTTGCAAAACCTTGATGTTGAGTTTCCAATGGGAGTTATGACGGCTGTAACTGGGGTT
TCTGGTTCTGGTAAATCAACTTTAGTTAACAGTATTTTAAAGAAATCATTAGCTCAAAAATTGAATCATAACTCAGAGAA
ACCTGGTAAGCATAAAAAAATTACTGGTTATGAAGGAATTGAGCGTTTGATTGATATTGACCAAAGTCCAATTGGTCGAA
CTCCACGTTCAAATCCGGCTACTTATACCAGCGTCTTTGATGACATTCGTGATTTATTTGCCAATACAAATGAAGCAAAA
ATTCGTGGTTATAAAAAAGGACGTTTCTCATTTAATGTTAAAGGTGGACGTTGTGAAGCCTGTTCTGGTGATGGAATCAT
CAAAATTGAAATGCATTTCTTGCCGGATGTTTATGTTCCATGTGAAGTTTGCCATGGCAGACGTTACAATTCAGAAACTT
TAGAAGTTCATTATAAAGGGAAGAATATTTCGGAAGTACTCGATATGCGCGTGTCTGATGGCTTGGAATTCTTCCGTCAT
ATTCCAAAAATTGAACGTAAACTCCAAACGATTGTTGATGTAGGTTTGGGATATGTGACGCTTGGACAATCAGCGACTAC
TTTATCAGGTGGGGAAGCTCAACGGATGAAATTAGCTTCTGAATTACAAAAACGTTCAAATGGTAAAGCTTTTTATATCT
TGGATGAACCAACAACTGGTTTGCACAGTGAAGATATTGCGACCCTGATTCAAGTATTAGACCGTTTGGTTGAACAAGGA
AATACAATTGTTGTCATTGAACATAATTTGGACGTTATTAAAACAGCAGATTACATCATCGACTTAGGTCCAGAAGGTGG
TGCTGGTGGTGGAACAATTCTTGCTAAAGGAAGACCAGAAGAAGTTGCAAAAGTTGCTGACAGCTATACTGGTCAGTATT
TGAAAGCAAAATTGGAAAAATAG

Domains

Predicted by InterProScan.

UvrA interaction domain (UvrA_inter)

(132-239)

ABC transporter (ABC_tran)

(622-858)

UvrA DNA-binding domain (UvrA_DNA-bind)

(289-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9CEL9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

77.447

100

0.774
  uvrA Streptococcus pneumoniae TIGR4

77.447

100

0.774
  uvrA Streptococcus pneumoniae D39

77.447

100

0.774

Multiple sequence alignment