Detailed information NTG0038474

Bioinformatically predicted

Overview

• Name: recD/recD2/recDB
• Type: Machinery gene
• Locus tag: CVCAS_RS08485
• Genome accession: NC_017486
• Coordinates: 1736259..1738763 (-)
• Length: 834 a.a.
• NCBI ID: WP_003132792.1
• Uniprot ID: Q9CEU4
• Organism: Lactococcus lactis subsp. lactis CV56
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1731259..1743763

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CVCAS_RS08455 (CVCAS_1662)	-	1731526..1731756 (-)	231	WP_014570685.1	helix-turn-helix transcriptional regulator	-
CVCAS_RS08460 (CVCAS_1663)	-	1731914..1732591 (+)	678	WP_014570686.1	helix-turn-helix transcriptional regulator	-
CVCAS_RS08465 (CVCAS_1664)	-	1732684..1733895 (+)	1212	WP_014570687.1	site-specific integrase	-
CVCAS_RS08470 (CVCAS_1665)	-	1734016..1734930 (-)	915	WP_012898318.1	diacylglycerol kinase family protein	-
CVCAS_RS08475 (CVCAS_1666)	-	1735087..1735599 (-)	513	WP_003132795.1	HD domain-containing protein	-
CVCAS_RS08480 (CVCAS_1667)	rpsT	1735932..1736165 (+)	234	WP_010906113.1	30S ribosomal protein S20	-
CVCAS_RS08485 (CVCAS_1669)	recD/recD2/recDB	1736259..1738763 (-)	2505	WP_003132792.1	ATP-dependent RecD-like DNA helicase	Machinery gene
CVCAS_RS08490 (CVCAS_1670)	-	1738760..1739353 (-)	594	WP_014570688.1	histidine phosphatase family protein	-
CVCAS_RS08495 (CVCAS_1671)	pheA	1739356..1740195 (-)	840	WP_014570689.1	prephenate dehydratase	-
CVCAS_RS08500 (CVCAS_1672)	-	1740197..1740685 (-)	489	WP_003132788.1	shikimate kinase	-
CVCAS_RS08505 (CVCAS_1673)	aroA	1740709..1742001 (-)	1293	WP_003132786.1	3-phosphoshikimate 1-carboxyvinyltransferase	-
CVCAS_RS08510 (CVCAS_1674)	-	1742122..1743186 (-)	1065	WP_014570690.1	prephenate dehydrogenase	-

Sequence

Protein

• Length: 834 a.a.
• Molecular weight: 92974.43 Da
• Isoelectric Point: 4.5085

>NTDB_id=38474 CVCAS_RS08485 WP_003132792.1 1736259..1738763(-) (recD/recD2/recDB) [Lactococcus lactis subsp. lactis CV56]
MIEKTYFTGSIEAIFFSNPSNFYKVLLIEIDETNAEYDDFEIVVNGTIGDVVEGDSYTFYGQLTQHPKYGEQLQVSQYEK
AVPTSGAGLVKYFSSDKFPGIGKKTAEKIVETFPENTVDSILEAPEKLDGLLTLARKNSFIKRLRENHGMEKVLTKLAEY
GLPSKITFQIYELYKEETIEKIEENPYQLVEDVKGVGFKTADKIASSLGIEADSPNRFRAALMHEVNTHSQSTGDTYIEA
KNLLEMTIDLLEEARNVEVNPSAVAEEINGLIVDGKVQQEGTKIFENSLYFAEDGIRKSLTALTNRSGKDFADEKLLTVL
AEVERDLEITYDDLQKQAIIGAMNQQFFILTGGPGTGKTTIINGFIETYARLHQLDLDPDHYNDDVFPILLAAPTGRASR
RMNELTGLPAATIHRHLGLGQDEAEDALGNELSGALLIVDEFSMVDTWLANKLFQAIPGSMKVLLVGDADQLPSVGPGQI
FADLLKIPEIPSVKLDKIFRQGDDSTITDLAHHIKDGQLPSDFTAKKPDRSYFEVSANFVPQMVEQIASAWQKRGNNPFE
LQILAPMYKGMAGINAMNVLLQNLFNPLNDRLEFALGDMKFREGDKVLHLVNDAEANVFNGDLGQIVELIAAKYTDSKQD
ELVMDFDGQELTYPRAEWYKITLAYAMSIHKSQGSEFSTVIVPMVSSYSRMLERNLLYTAITRAKQSLILLGEERAFAQA
VAREGANRKTYLIERFMGENPAAKNLSVEIVSEKVTDKKERSDKEKKPAAPVELQGQIRSVSKKMPAQVEEISLFEDEEI
ETLDKGSLTEALILSGNFDPLIGLTQQDFAIFNK

Nucleotide

• Length: 2505 bp

>NTDB_id=38474 CVCAS_RS08485 WP_003132792.1 1736259..1738763(-) (recD/recD2/recDB) [Lactococcus lactis subsp. lactis CV56]
ATGATTGAAAAAACTTATTTTACTGGTTCGATTGAGGCAATATTTTTCTCCAATCCCAGTAATTTTTATAAAGTTCTACT
CATTGAAATTGATGAAACTAATGCTGAATATGATGATTTTGAAATTGTGGTTAACGGGACAATTGGGGATGTGGTTGAAG
GAGATTCTTATACATTTTATGGTCAATTGACGCAGCATCCTAAATATGGGGAACAATTACAGGTCAGTCAATATGAAAAA
GCAGTGCCGACTTCTGGTGCTGGTTTAGTTAAATATTTTTCTTCAGATAAATTTCCTGGAATTGGTAAGAAAACGGCAGA
AAAAATTGTTGAAACTTTTCCTGAAAATACGGTAGATTCAATTTTAGAAGCGCCGGAGAAATTGGATGGTCTATTGACCC
TAGCCAGAAAAAATTCATTTATCAAACGATTACGTGAGAATCATGGAATGGAAAAAGTGCTGACCAAGCTTGCAGAATAT
GGCTTACCAAGCAAAATCACTTTTCAAATTTATGAACTTTATAAAGAAGAAACGATTGAAAAAATTGAGGAAAATCCTTA
TCAGCTTGTGGAAGATGTTAAGGGAGTTGGTTTTAAAACAGCTGATAAGATTGCAAGTAGTTTAGGAATTGAAGCGGATA
GCCCTAATCGATTTCGAGCGGCATTGATGCATGAGGTCAATACACATTCGCAATCAACAGGCGATACTTACATTGAAGCC
AAAAATTTACTTGAGATGACGATAGACTTACTTGAAGAAGCTCGTAATGTCGAGGTCAACCCGTCTGCTGTTGCGGAGGA
AATTAATGGTTTAATAGTTGATGGAAAAGTGCAACAAGAAGGAACAAAAATATTTGAGAATTCCTTGTACTTCGCTGAGG
ACGGGATTCGGAAATCACTGACAGCATTAACTAATCGTTCGGGTAAAGATTTTGCTGATGAAAAGTTACTGACAGTATTG
GCTGAAGTTGAAAGAGATTTAGAAATTACTTATGATGATTTGCAAAAGCAAGCCATTATTGGTGCAATGAATCAGCAATT
TTTCATTTTGACTGGTGGACCAGGAACTGGTAAAACAACAATTATTAATGGTTTTATTGAAACTTATGCCCGTCTTCATC
AGCTAGATTTGGACCCAGACCATTATAATGATGACGTCTTTCCTATATTACTGGCAGCACCGACTGGTCGAGCTTCAAGA
CGGATGAATGAGTTGACTGGTCTTCCAGCAGCGACGATTCACCGCCATTTGGGTTTGGGACAAGATGAAGCAGAAGATGC
TCTTGGAAATGAATTGTCTGGTGCTCTTTTGATTGTTGACGAATTTTCTATGGTTGATACTTGGTTAGCTAATAAACTTT
TTCAAGCGATTCCTGGTTCAATGAAAGTTCTCCTTGTTGGAGATGCTGACCAGCTTCCTTCTGTGGGGCCAGGACAAATT
TTTGCGGATTTACTAAAAATTCCAGAAATTCCGTCAGTAAAATTGGATAAGATTTTTCGTCAAGGGGATGATTCTACCAT
TACTGATTTAGCTCACCACATCAAAGATGGGCAATTGCCAAGTGATTTCACGGCGAAAAAACCTGACCGTTCTTATTTTG
AGGTCAGTGCAAATTTTGTTCCTCAGATGGTTGAACAAATCGCAAGTGCATGGCAAAAAAGAGGGAATAATCCTTTTGAA
TTACAAATCTTAGCGCCTATGTATAAAGGAATGGCCGGAATTAATGCAATGAATGTTCTTTTGCAAAATCTCTTTAATCC
GCTTAATGACCGACTTGAATTTGCTTTGGGTGATATGAAATTTCGTGAAGGAGATAAAGTTCTTCATTTAGTAAATGATG
CTGAGGCCAATGTATTTAACGGAGATTTGGGACAAATCGTAGAATTGATTGCAGCAAAATATACTGATAGTAAACAAGAT
GAGTTGGTGATGGATTTTGATGGTCAAGAATTGACTTATCCAAGAGCGGAGTGGTATAAAATTACTCTGGCTTATGCGAT
GTCCATTCATAAATCTCAAGGTTCGGAGTTTTCCACAGTTATTGTGCCGATGGTTTCTTCGTATTCACGCATGTTAGAGC
GAAATTTGCTTTATACGGCAATTACAAGGGCTAAACAAAGTCTGATTTTACTTGGTGAAGAACGAGCTTTTGCACAAGCG
GTGGCGCGTGAAGGAGCGAATCGAAAGACCTATCTGATTGAGCGATTTATGGGAGAAAATCCAGCGGCTAAAAATCTGTC
AGTAGAAATTGTGAGTGAAAAAGTTACTGACAAAAAAGAAAGATCTGACAAAGAGAAGAAGCCTGCAGCGCCAGTAGAAT
TACAAGGGCAAATTCGTTCTGTCAGTAAAAAAATGCCAGCACAAGTAGAAGAAATTTCTTTATTTGAAGATGAAGAAATT
GAAACACTGGATAAGGGAAGCTTGACAGAAGCACTTATTTTGTCAGGAAATTTTGACCCTTTAATTGGTTTAACTCAACA
AGACTTTGCAATCTTTAATAAATAA

Domains

Predicted by InterProScan.

• ATP-dependent RecD-like DNA helicase SH3 domain (SH3_13) (577-646)

• AAA domain (AAA_30) (331-522)

• UvrD-like helicase C-terminal domain (UvrD_C_2) (664-710)

• Helix-hairpin-helix containing domain (HHH_RecD2) (146-237)

3D structure

• AlphaFold DB: Q9CEU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
recD/recD2/recDB	Bacillus subtilis subsp. subtilis str. 168	42.175	90.408	0.381