Detailed information NTG0038464

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: CVCAS_RS07295
• Genome accession: NC_017486
• Coordinates: 1496436..1499039 (-)
• Length: 867 a.a.
• NCBI ID: WP_003130040.1
• Uniprot ID: Q9CFF3
• Organism: Lactococcus lactis subsp. lactis CV56
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1491436..1504039

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CVCAS_RS07275 (CVCAS_1427)	-	1492319..1492849 (+)	531	WP_003130052.1	TetR/AcrR family transcriptional regulator	-
CVCAS_RS13465	-	1492900..1493088 (-)	189	WP_003130050.1	hypothetical protein	-
CVCAS_RS13470	-	1493116..1493760 (-)	645	WP_232626159.1	ABC transporter ATP-binding protein	-
CVCAS_RS13475	-	1493769..1494488 (-)	720	WP_003130046.1	ABC transporter transmembrane domain-containing protein	-
CVCAS_RS07285 (CVCAS_1429)	purN	1494655..1495203 (-)	549	WP_003130044.1	phosphoribosylglycinamide formyltransferase	-
CVCAS_RS07290 (CVCAS_1430)	purM	1495231..1496253 (-)	1023	WP_003130042.1	phosphoribosylformylglycinamidine cyclo-ligase	-
CVCAS_RS07295 (CVCAS_1431)	clpC	1496436..1499039 (-)	2604	WP_003130040.1	ATP-dependent chaperone ClpB	Regulator
CVCAS_RS07300 (CVCAS_1432)	-	1499273..1500613 (+)	1341	WP_014570652.1	hypothetical protein	-
CVCAS_RS07305 (CVCAS_1433)	-	1500646..1501269 (-)	624	WP_003130037.1	NAD-dependent epimerase/dehydratase family protein	-
CVCAS_RS07310 (CVCAS_1434)	purF	1501379..1502878 (-)	1500	WP_003130036.1	amidophosphoribosyltransferase	-
CVCAS_RS07315 (CVCAS_1435)	-	1502993..1503837 (-)	845	Protein_1420	oxidoreductase	-

Sequence

Protein

• Length: 867 a.a.
• Molecular weight: 97335.08 Da
• Isoelectric Point: 4.8188

>NTDB_id=38464 CVCAS_RS07295 WP_003130040.1 1496436..1499039(-) (clpC) [Lactococcus lactis subsp. lactis CV56]
MDIEKMTTTMQEALGSAQQIAQVRHHQVIEVPHLWRIFVQPNSFGANFYKDLGIDLDDYTNLIEKEIDKINSVEGSNITY
GQNLSPDLFQIFTEADKIAQKMGDEYLSTEIILLALFELKQNPLTSYLVSHGLTKAKAQAAIEKLRGGDKVTSQNAEETY
KALEKYGVDLVAQVKSGKQDPVIGRDEEIRDVIRVLSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVRKDVPENLKDKTIF
SLDMGALIAGAKYRGEFEERLKAVLNEVKKSDGQIILFIDELHTIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDE
YRKYMETDKALERRFQKVLVTEPTVEDTISILRGLKERFEIHHGVTIHDNALVAAATLSNRYITDRFLPDKAIDLVDEAS
ATIRVEMNSLPTELDQANRRLMQLEIEEAALKKERDDASKKRLEIIRGEIAELREENNQLKAQWEAEKKEVGNISEKRNE
LEHARHELEEAQNEGNLEKAAALRYGKIPEIEKELKAIEEKAKSDDLSLVQESVTEEQITEVVGRMTGIPITKLVEGERE
KLLHLPETLHQRVVGQDEAVEAVSDAIIRARAGIQDPNRPLGSFLFLGPTGVGKTELAKALAENLFDSEEHMVRIDMSEY
MEKHSVSRLVGAPPGYVGYDEGGQLTEAVRRNPYTIILLDEIEKAHPDVFNILLQVLDDGRLTDSKGVLVDFKNTVLIMT
SNVGSQYLLDNVGENGEISEETTENVMSQLRAHFKPEFLNRIDDTILFKPLALEDIKNIIVKMTSQLSHRLEEMDVQLEL
SEEVKVWIAENAYEPAYGARPLKRYLTKVIENPLAKLIIGGKIPPKSKVIVTLVENKIDFDIQTIAE

Nucleotide

• Length: 2604 bp

>NTDB_id=38464 CVCAS_RS07295 WP_003130040.1 1496436..1499039(-) (clpC) [Lactococcus lactis subsp. lactis CV56]
ATGGACATCGAAAAAATGACAACAACGATGCAAGAAGCACTTGGTTCAGCGCAACAAATTGCGCAAGTTCGTCATCACCA
AGTGATTGAAGTTCCACATTTATGGCGAATTTTTGTTCAACCTAATAGTTTTGGGGCGAACTTTTATAAAGATTTAGGGA
TTGACCTAGATGACTATACAAATTTAATTGAAAAAGAAATTGACAAAATTAATTCAGTAGAAGGTTCAAATATTACTTAT
GGTCAAAACCTAAGTCCAGATTTGTTCCAAATATTTACTGAAGCAGACAAAATTGCGCAAAAAATGGGCGATGAATACTT
ATCAACTGAGATTATTCTCCTTGCCCTCTTTGAATTAAAACAAAATCCATTGACCAGTTATTTGGTTAGCCATGGACTAA
CAAAAGCAAAAGCGCAAGCTGCAATTGAAAAATTACGCGGAGGTGATAAAGTGACCAGTCAAAATGCAGAAGAAACATAC
AAAGCACTTGAAAAATATGGGGTAGATCTCGTTGCTCAAGTTAAATCAGGTAAACAAGATCCTGTCATTGGACGTGATGA
AGAAATTCGTGATGTCATTCGAGTGCTTTCTCGTAAAACAAAAAATAACCCCGTTCTTATTGGTGAACCTGGGGTTGGTA
AAACAGCCATTGTTGAAGGATTGGCACAAAGGATTGTCAGAAAAGACGTTCCTGAAAATCTGAAAGATAAAACAATCTTT
TCACTTGATATGGGTGCCCTGATTGCAGGAGCGAAATATCGTGGTGAATTTGAAGAACGTTTGAAAGCAGTCCTTAATGA
AGTGAAAAAATCAGATGGACAAATTATCCTCTTTATTGATGAACTTCATACGATTGTTGGTGCAGGTAAAACAGAAGGTT
CAATGGACGCTGGGAACCTTTTAAAACCAATGCTTGCACGTGGTGAACTCCATTTGATTGGGGCAACTACCTTGGATGAA
TATCGTAAATACATGGAAACAGATAAAGCACTTGAACGTCGTTTCCAAAAGGTATTGGTTACTGAACCTACTGTTGAAGA
TACAATTTCAATCTTGCGTGGTCTAAAAGAACGTTTTGAAATTCACCATGGAGTGACCATTCATGATAATGCTTTAGTCG
CAGCAGCAACCCTTTCAAATCGTTATATTACTGACCGATTTTTACCAGATAAAGCCATTGACTTGGTTGATGAAGCCAGT
GCAACAATTCGTGTAGAAATGAATTCACTCCCAACTGAACTTGACCAAGCTAATCGTCGCTTGATGCAATTAGAAATTGA
AGAAGCGGCCCTCAAAAAAGAACGAGATGATGCTTCTAAGAAACGTCTTGAAATTATACGTGGTGAAATTGCTGAACTTC
GAGAAGAAAATAATCAACTCAAAGCTCAATGGGAAGCTGAGAAAAAAGAAGTGGGCAATATTTCTGAAAAACGAAATGAA
TTAGAACATGCTCGCCACGAATTGGAAGAAGCTCAAAATGAAGGAAACTTAGAAAAAGCAGCAGCCCTTCGTTATGGTAA
AATTCCTGAAATTGAAAAAGAACTCAAAGCTATTGAAGAAAAAGCAAAATCAGATGATTTATCCTTAGTTCAAGAATCAG
TCACTGAAGAACAAATCACTGAAGTTGTTGGACGCATGACAGGTATTCCAATTACCAAATTGGTTGAAGGTGAACGTGAA
AAATTACTTCACTTGCCAGAAACACTGCATCAAAGGGTCGTTGGACAAGATGAAGCTGTTGAAGCCGTATCTGATGCCAT
TATTCGTGCGCGTGCAGGAATTCAAGACCCTAATCGTCCACTTGGCTCATTCCTCTTCCTCGGTCCAACTGGGGTAGGTA
AGACCGAACTCGCGAAAGCTTTGGCTGAAAATCTCTTTGATTCAGAAGAACATATGGTTCGGATTGACATGAGTGAATAT
ATGGAAAAACACTCAGTTTCTCGGTTAGTCGGAGCACCTCCAGGATATGTCGGTTACGATGAAGGAGGCCAATTGACTGA
AGCTGTTCGTCGTAATCCTTATACAATCATCTTGCTTGATGAAATCGAAAAAGCACATCCAGATGTCTTCAATATCTTGT
TGCAAGTTTTGGATGACGGCCGTTTGACTGACTCTAAAGGTGTTCTCGTTGACTTTAAGAACACAGTGTTGATTATGACT
TCAAATGTCGGTTCTCAATATTTGCTTGATAATGTTGGAGAAAATGGTGAAATTTCGGAAGAAACAACTGAAAACGTGAT
GTCTCAACTTCGGGCACATTTCAAACCAGAATTTCTAAATCGAATTGATGATACCATTCTTTTCAAACCATTGGCACTTG
AGGATATTAAGAATATTATCGTTAAAATGACTAGCCAACTTTCACATCGTCTTGAAGAAATGGATGTTCAACTTGAGTTG
AGTGAAGAAGTAAAAGTTTGGATTGCCGAAAATGCTTATGAACCAGCTTATGGTGCACGTCCACTCAAACGTTATTTGAC
AAAAGTCATCGAAAATCCATTAGCTAAGCTGATTATCGGAGGAAAAATTCCACCAAAATCAAAAGTTATTGTAACGCTTG
TAGAAAACAAGATTGACTTTGATATTCAAACGATTGCTGAATAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (599-764)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (771-851)

• AAA lid domain (AAA_lid_9) (344-444)

• ATPase family associated with various cellular activities (AAA) (AAA) (205-339)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-147)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-67)

3D structure

• AlphaFold DB: Q9CFF3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	45.444	100	0.46
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	40.935	100	0.414