Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   FZE25_RS14900 Genome accession   NZ_CP043416
Coordinates   2995094..2995738 (-) Length   214 a.a.
NCBI ID   WP_003152052.1    Uniprot ID   A3KLB8
Organism   Bacillus velezensis strain ONU 553     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 2990094..3000738
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FZE25_RS14865 (FZE25_14615) - 2991279..2991710 (+) 432 WP_007408670.1 Na(+)/H(+) antiporter subunit B -
  FZE25_RS14870 (FZE25_14620) - 2991710..2992051 (+) 342 WP_003152063.1 Na(+)/H(+) antiporter subunit C -
  FZE25_RS14875 (FZE25_14625) - 2992044..2993525 (+) 1482 WP_042635451.1 Na+/H+ antiporter subunit D -
  FZE25_RS14880 (FZE25_14630) - 2993531..2994007 (+) 477 WP_007408672.1 Na+/H+ antiporter subunit E -
  FZE25_RS14885 (FZE25_14635) - 2994007..2994291 (+) 285 WP_012118311.1 Na(+)/H(+) antiporter subunit F1 -
  FZE25_RS14890 (FZE25_14640) mnhG 2994275..2994649 (+) 375 WP_003152056.1 monovalent cation/H(+) antiporter subunit G -
  FZE25_RS14895 (FZE25_14645) - 2994689..2995072 (-) 384 WP_007408674.1 hotdog fold thioesterase -
  FZE25_RS14900 (FZE25_14650) comA 2995094..2995738 (-) 645 WP_003152052.1 response regulator transcription factor Regulator
  FZE25_RS14905 (FZE25_14655) comP 2995819..2998110 (-) 2292 WP_042635452.1 histidine kinase Regulator
  FZE25_RS14910 (FZE25_14660) comX 2998122..2998286 (-) 165 WP_007613432.1 competence pheromone ComX -
  FZE25_RS14915 (FZE25_14665) - 2998286..2999197 (-) 912 WP_079891433.1 polyprenyl synthetase family protein -
  FZE25_RS14920 (FZE25_14670) degQ 2999349..2999489 (-) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  FZE25_RS14930 (FZE25_14675) - 2999954..3000295 (+) 342 WP_042635453.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24271.68 Da        Isoelectric Point: 4.9953

>NTDB_id=383704 FZE25_RS14900 WP_003152052.1 2995094..2995738(-) (comA) [Bacillus velezensis strain ONU 553]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTPRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=383704 FZE25_RS14900 WP_003152052.1 2995094..2995738(-) (comA) [Bacillus velezensis strain ONU 553]
ATGAAAAAGATACTAGTGATTGATGATCATCCAGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGATGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATAGAGCTTTCTAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTGCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACCCCGAGAGAGCGCCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCACTTCACTTAAGCAAGCGGTCAATTGAATA
CAGCCTGACATCCATTTTTAACAAGCTGAATGTCGGCTCCCGAACTGAAGCGGTGCTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3KLB8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

86.449

100

0.864

Multiple sequence alignment