Detailed information NTG0383232

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: FZC51_RS14305
• Genome accession: NZ_CP043389
• Coordinates: 2774788..2775675 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain NRS384-rpoB-H481N-SCV
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2769788..2780675

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FZC51_RS14270 (FZC51_14270)	-	2769807..2769899 (+)	93	WP_010956583.1	hypothetical protein	-
FZC51_RS14275 (FZC51_14275)	-	2770007..2770504 (-)	498	WP_001065268.1	glutathione peroxidase	-
FZC51_RS14280 (FZC51_14280)	-	2770514..2770774 (-)	261	WP_001789910.1	hypothetical protein	-
FZC51_RS14290 (FZC51_14290)	-	2771156..2771269 (-)	114	WP_001791776.1	hypothetical protein	-
FZC51_RS14295 (FZC51_14295)	-	2771928..2773928 (-)	2001	WP_000776751.1	ABC transporter permease	-
FZC51_RS14300 (FZC51_14300)	-	2773925..2774680 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
FZC51_RS14305 (FZC51_14305)	braS	2774788..2775675 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
FZC51_RS14310 (FZC51_14310)	braR	2775686..2776351 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
FZC51_RS14315 (FZC51_14315)	-	2776377..2776577 (-)	201	WP_000604728.1	hypothetical protein	-
FZC51_RS14320 (FZC51_14320)	-	2776775..2778199 (+)	1425	WP_000953744.1	alkaline phosphatase	-
FZC51_RS15035 (FZC51_14325)	-	2778259..2778360 (-)	102	WP_000731972.1	SE2200 family small protein	-
FZC51_RS14330 (FZC51_14330)	-	2778482..2778937 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
FZC51_RS14335 (FZC51_14335)	-	2779182..2779943 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=383232 FZC51_RS14305 WP_000143419.1 2774788..2775675(-) (braS) [Staphylococcus aureus strain NRS384-rpoB-H481N-SCV]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=383232 FZC51_RS14305 WP_000143419.1 2774788..2775675(-) (braS) [Staphylococcus aureus strain NRS384-rpoB-H481N-SCV]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997