Detailed information NTG0038319

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SP670_RS10300
• Genome accession: NC_014498
• Coordinates: 1912020..1913057 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727273.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae 670-6B
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1907020..1918057

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SP670_RS10275 (SP670_2041)	-	1907821..1909152 (-)	1332	WP_000390049.1	hemolysin family protein	-
SP670_RS10280 (SP670_2042)	endA	1909381..1910205 (-)	825	WP_001036791.1	DNA-entry nuclease EndA	Machinery gene
SP670_RS10285 (SP670_2043)	-	1910244..1910432 (-)	189	WP_013315459.1	DNA-directed RNA polymerase subunit beta	-
SP670_RS10290 (SP670_2044)	murA	1910425..1911708 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
SP670_RS10295 (SP670_2045)	-	1911732..1911962 (-)	231	WP_000250392.1	DUF1146 family protein	-
SP670_RS10300 (SP670_2046)	sepM	1912020..1913057 (-)	1038	WP_000727273.1	SepM family pheromone-processing serine protease	Regulator
SP670_RS10305 (SP670_2047)	coaD	1913041..1913529 (-)	489	WP_001280736.1	pantetheine-phosphate adenylyltransferase	-
SP670_RS10310 (SP670_2048)	rsmD	1913519..1914058 (-)	540	WP_000706966.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SP670_RS10315 (SP670_2049)	asnA	1914123..1915115 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
SP670_RS10325 (SP670_2050)	-	1915227..1915910 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
SP670_RS10330 (SP670_2051)	-	1915966..1916706 (-)	741	WP_000152680.1	RNA methyltransferase	-
SP670_RS10335 (SP670_2052)	-	1916740..1917018 (+)	279	WP_001174613.1	acylphosphatase	-
SP670_RS10340 (SP670_2053)	yidC	1917096..1918022 (+)	927	WP_000835955.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37519.54 Da
• Isoelectric Point: 5.0724

>NTDB_id=38319 SP670_RS10300 WP_000727273.1 1912020..1913057(-) (sepM) [Streptococcus pneumoniae 670-6B]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFLRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=38319 SP670_RS10300 WP_000727273.1 1912020..1913057(-) (sepM) [Streptococcus pneumoniae 670-6B]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTCTGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588