Detailed information NTG0382746

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: FQP84_RS15160
• Genome accession: NZ_CP043302
• Coordinates: 2903442..2904485 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 16445
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2898442..2909485

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FQP84_RS15130 (FQP84_15130)	-	2898860..2900116 (-)	1257	WP_001795438.1	aminopeptidase	-
FQP84_RS15135 (FQP84_15135)	-	2900119..2900319 (-)	201	WP_000180461.1	DUF1128 family protein	-
FQP84_RS15140 (FQP84_15140)	-	2900466..2900930 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
FQP84_RS15145 (FQP84_15145)	-	2900937..2901212 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
FQP84_RS15150 (FQP84_15150)	-	2901490..2902707 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
FQP84_RS15155 (FQP84_15155)	vraR	2902823..2903452 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
FQP84_RS15160 (FQP84_15160)	vraS	2903442..2904485 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
FQP84_RS15165 (FQP84_15165)	liaF	2904482..2905183 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
FQP84_RS15170 (FQP84_15170)	-	2905198..2905584 (-)	387	WP_001110179.1	hypothetical protein	-
FQP84_RS15175 (FQP84_15175)	map	2905801..2906559 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
FQP84_RS15180 (FQP84_15180)	-	2907146..2908153 (+)	1008	WP_149590313.1	aromatic acid exporter family protein	-
FQP84_RS15185 (FQP84_15185)	-	2908584..2908997 (-)	414	WP_001549145.1	hypothetical protein	-
FQP84_RS15190 (FQP84_15190)	-	2909026..2909136 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=382746 FQP84_RS15160 WP_001017131.1 2903442..2904485(-) (vraS) [Staphylococcus aureus strain 16445]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=382746 FQP84_RS15160 WP_001017131.1 2903442..2904485(-) (vraS) [Staphylococcus aureus strain 16445]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1