Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   HCU71_RS12705 Genome accession   NZ_CP050691
Coordinates   2586455..2587168 (+) Length   237 a.a.
NCBI ID   WP_001031454.1    Uniprot ID   A0A0H2XG68
Organism   Staphylococcus aureus strain PMB196-1     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2581455..2592168
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HCU71_RS12640 (HCU71_12640) - 2582205..2582468 (-) 264 WP_001205732.1 hypothetical protein -
  HCU71_RS12645 (HCU71_12645) - 2582477..2582737 (-) 261 WP_000291503.1 DUF1108 family protein -
  HCU71_RS12650 (HCU71_12650) - 2582718..2583044 (-) 327 WP_000165375.1 DUF2482 family protein -
  HCU71_RS12655 (HCU71_12655) - 2583139..2583300 (-) 162 WP_000066017.1 DUF1270 domain-containing protein -
  HCU71_RS12660 (HCU71_12660) - 2583297..2583617 (-) 321 WP_001120197.1 DUF771 domain-containing protein -
  HCU71_RS12665 (HCU71_12665) - 2583676..2584308 (+) 633 WP_000275058.1 hypothetical protein -
  HCU71_RS12670 (HCU71_12670) - 2584323..2584463 (-) 141 WP_000939496.1 hypothetical protein -
  HCU71_RS12675 (HCU71_12675) - 2584494..2584691 (-) 198 WP_001148855.1 hypothetical protein -
  HCU71_RS12680 (HCU71_12680) - 2584707..2585459 (-) 753 WP_001148605.1 phage antirepressor KilAC domain-containing protein -
  HCU71_RS12685 (HCU71_12685) - 2585510..2585839 (+) 330 WP_000128907.1 hypothetical protein -
  HCU71_RS12690 (HCU71_12690) - 2585828..2586043 (-) 216 WP_167780481.1 DUF2829 domain-containing protein -
  HCU71_RS12695 (HCU71_12695) - 2586059..2586322 (-) 264 WP_167780482.1 helix-turn-helix transcriptional regulator -
  HCU71_RS12700 (HCU71_12700) - 2586319..2586492 (-) 174 WP_001801500.1 hypothetical protein -
  HCU71_RS12705 (HCU71_12705) irvR 2586455..2587168 (+) 714 WP_001031454.1 XRE family transcriptional regulator Regulator
  HCU71_RS12710 (HCU71_12710) - 2587184..2588116 (+) 933 WP_000759682.1 exonuclease domain-containing protein -
  HCU71_RS12715 (HCU71_12715) - 2588122..2588463 (+) 342 WP_000591749.1 hypothetical protein -
  HCU71_RS12720 (HCU71_12720) - 2588667..2588849 (+) 183 WP_000705248.1 hypothetical protein -
  HCU71_RS12725 (HCU71_12725) - 2588949..2589413 (+) 465 WP_000825947.1 hypothetical protein -
  HCU71_RS12730 (HCU71_12730) - 2589472..2590509 (+) 1038 WP_167780483.1 site-specific integrase -
  HCU71_RS12735 (HCU71_12735) sph 2590560..2591390 (+) 831 Protein_2472 sphingomyelin phosphodiesterase -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27017.58 Da        Isoelectric Point: 5.0545

>NTDB_id=381684 HCU71_RS12705 WP_001031454.1 2586455..2587168(+) (irvR) [Staphylococcus aureus strain PMB196-1]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide


Download         Length: 714 bp        

>NTDB_id=381684 HCU71_RS12705 WP_001031454.1 2586455..2587168(+) (irvR) [Staphylococcus aureus strain PMB196-1]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTACGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(127-236)

Helix-turn-helix (HTH_3)

(13-63)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XG68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

33.929

100

0.401

Multiple sequence alignment