Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACAN_RS05075 Genome accession   NZ_CP042812
Coordinates   995934..997766 (-) Length   610 a.a.
NCBI ID   WP_099334054.1    Uniprot ID   -
Organism   Malaciobacter canalis strain LMG 29148     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 990934..1002766
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACAN_RS05050 (ACAN_1009) - 992124..992765 (-) 642 WP_099334049.1 adenylate kinase -
  ACAN_RS05055 (ACAN_1010) - 992876..993460 (+) 585 WP_099334050.1 adenylate kinase -
  ACAN_RS05060 (ACAN_1011) - 993463..994233 (+) 771 WP_099334051.1 competence/damage-inducible protein A -
  ACAN_RS05065 (ACAN_1012) - 994236..994904 (-) 669 WP_099334052.1 tetratricopeptide repeat protein -
  ACAN_RS05070 (ACAN_1013) - 994901..995923 (-) 1023 WP_099334053.1 alanine racemase -
  ACAN_RS05075 (ACAN_1014) uvrC 995934..997766 (-) 1833 WP_099334054.1 excinuclease ABC subunit UvrC Machinery gene
  ACAN_RS05080 (ACAN_1015) - 997803..998711 (-) 909 WP_099334055.1 hypothetical protein -
  ACAN_RS05085 (ACAN_1016) - 998809..999576 (-) 768 WP_170233020.1 choline/ethanolamine kinase family protein -
  ACAN_RS05090 (ACAN_1017) pnuC 999560..1000168 (-) 609 WP_322863337.1 nicotinamide riboside transporter PnuC -
  ACAN_RS05095 (ACAN_1018) - 1000287..1000565 (+) 279 WP_079577027.1 putative quinol monooxygenase -
  ACAN_RS05100 (ACAN_1019) - 1000576..1001211 (+) 636 WP_099334057.1 hypothetical protein -
  ACAN_RS05105 (ACAN_1020) - 1001208..1001708 (-) 501 WP_099334058.1 SprT-like domain-containing protein -
  ACAN_RS05110 (ACAN_1021) - 1001712..1002017 (-) 306 WP_228145268.1 J domain-containing protein -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 71402.90 Da        Isoelectric Point: 9.5500

>NTDB_id=378713 ACAN_RS05075 WP_099334054.1 995934..997766(-) (uvrC) [Malaciobacter canalis strain LMG 29148]
MNLEEKLKELPNSAGVYQYFNKDGHLLYIGKAKVLKNRVKSYFKFTPNLAPADKLSPRIYKMITEVKSLEWIIVPNEHDA
LILENSLIKQLKPKYNILLRDDKTYPYIVIDYKEDFPRLEITRRVLKDKNIKYFGPYSTGARDMLDSIYEIIPLVQKKSC
IKGKEACLFHQIKKCYAPCVGKISKEEYSKIVDEALEYIYNKNKLIKKLNERMLQYSEEFRFEEAMKIRDRIKTIEKSQI
HTGMDLASNDNLDLFAIKASKEKAVIVRMFFRDGKLASSNHDYLKINQKELDIDLNEAYKRAIINYYDNEIPLLPKEIVV
ADEITQEIEELQEFIKDRFEKNIPIIHPKRGKKTQIIKIAINNCNELLRLQNSNATTIYKQLQELLNLSYTPNRFECFDN
SHMMGQATVGAMITWEEKFIKADYRHYNLEAKDEYAQMKETLIRRVQSFEKNPAPDVWVIDGGETLLKLAIDIRNSVGVN
LDIIAIAKEKLDFKAHRAKGSAKDIIYFEENNSIKRVDLLPSDKRLQFIQRLRDEAHRFAISFHKKQKRKDDSKISLLQI
KGIGEAKVKKLLLYFGEFEKIKNASFNELQVVLNKKDASLLIDYFKTLDN

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=378713 ACAN_RS05075 WP_099334054.1 995934..997766(-) (uvrC) [Malaciobacter canalis strain LMG 29148]
ATGAACTTAGAAGAGAAACTTAAAGAATTACCAAATAGTGCTGGTGTTTATCAGTACTTTAATAAAGATGGACACTTACT
TTATATAGGAAAAGCAAAGGTACTAAAAAATAGAGTTAAATCATATTTTAAATTTACTCCTAATTTAGCACCAGCTGATA
AATTAAGTCCTAGAATTTACAAAATGATAACAGAAGTAAAATCTTTAGAGTGGATTATTGTACCAAATGAACATGATGCA
CTTATACTTGAAAATTCACTTATTAAACAACTTAAACCAAAATACAATATTTTATTAAGAGATGATAAAACATATCCTTA
TATTGTTATTGATTATAAAGAGGATTTTCCAAGATTAGAGATAACAAGAAGAGTTTTAAAAGATAAAAATATCAAATACT
TTGGTCCATATTCTACTGGTGCTAGAGATATGCTTGATAGTATTTATGAAATAATTCCTTTAGTACAAAAAAAATCTTGT
ATAAAAGGAAAAGAAGCTTGTCTTTTTCATCAGATAAAAAAATGTTATGCTCCTTGTGTTGGAAAAATTTCAAAAGAAGA
GTATAGTAAAATAGTTGATGAAGCCTTAGAGTATATTTACAATAAAAATAAGTTAATTAAGAAATTAAATGAAAGAATGC
TTCAATACTCCGAAGAGTTTAGATTTGAAGAAGCCATGAAAATTAGAGATAGAATAAAAACTATTGAAAAATCTCAAATC
CACACAGGAATGGATTTAGCAAGTAATGATAATCTAGATTTATTTGCAATAAAAGCATCAAAAGAAAAAGCCGTAATAGT
AAGAATGTTTTTTAGAGATGGCAAGTTAGCTTCAAGTAACCATGATTATTTAAAAATAAATCAAAAAGAGCTTGACATAG
ACTTAAATGAAGCATATAAAAGAGCAATAATTAACTACTATGACAATGAAATTCCTCTACTACCAAAAGAGATAGTTGTA
GCTGATGAGATAACACAAGAAATTGAAGAGCTACAAGAGTTTATAAAAGATAGATTTGAAAAAAATATTCCAATTATTCA
TCCAAAAAGAGGAAAGAAAACACAAATTATAAAAATTGCAATAAATAATTGCAATGAGCTTTTAAGACTTCAAAATAGTA
ATGCAACTACTATTTATAAACAACTACAAGAGTTATTAAACCTTTCATATACACCAAATAGATTTGAATGCTTTGATAAT
TCACATATGATGGGACAAGCAACAGTTGGTGCAATGATTACTTGGGAAGAGAAGTTTATAAAAGCAGATTATAGACACTA
TAATCTTGAAGCAAAAGATGAATATGCACAAATGAAAGAAACATTAATAAGAAGAGTACAAAGTTTTGAAAAAAATCCAG
CACCTGATGTTTGGGTTATTGATGGAGGAGAAACTTTATTAAAACTTGCAATTGATATAAGAAACTCAGTAGGAGTAAAT
CTTGATATAATTGCAATAGCAAAAGAAAAACTTGATTTTAAAGCACATAGAGCAAAAGGAAGTGCAAAAGATATAATCTA
TTTTGAAGAAAATAATAGTATTAAAAGAGTTGATTTACTTCCAAGTGATAAAAGATTACAATTTATTCAAAGATTAAGAG
ATGAAGCACATAGATTTGCAATCTCTTTTCATAAAAAACAAAAAAGAAAAGATGATAGTAAAATATCTTTACTTCAAATA
AAAGGAATAGGTGAAGCTAAAGTCAAAAAACTTCTTTTATATTTTGGAGAGTTTGAAAAAATAAAAAATGCATCTTTTAA
TGAGCTTCAAGTAGTATTAAACAAAAAAGATGCTTCTTTATTAATTGACTATTTTAAAACATTAGATAACTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(204-237)

GIY-YIG catalytic domain (GIY-YIG)

(15-96)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(383-541)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

51.171

98.033

0.502

Multiple sequence alignment