Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   AACT_RS05215 Genome accession   NZ_CP042652
Coordinates   995159..997009 (-) Length   616 a.a.
NCBI ID   WP_172125610.1    Uniprot ID   A0A6M8EE22
Organism   Arcobacter acticola strain KCTC 52212     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 990159..1002009
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AACT_RS05190 (AACT_1025) - 991216..991857 (-) 642 WP_172125600.1 adenylate kinase -
  AACT_RS05195 (AACT_1026) - 991989..992573 (+) 585 WP_172125602.1 adenylate kinase -
  AACT_RS05200 (AACT_1027) - 992580..993338 (+) 759 WP_172125604.1 molybdopterin-binding protein -
  AACT_RS05205 (AACT_1028) - 993472..994137 (-) 666 WP_172125606.1 tetratricopeptide repeat protein -
  AACT_RS05210 (AACT_1029) - 994134..995156 (-) 1023 WP_172125608.1 alanine racemase -
  AACT_RS05215 (AACT_1030) uvrC 995159..997009 (-) 1851 WP_172125610.1 excinuclease ABC subunit UvrC Machinery gene
  AACT_RS05220 (AACT_1031) - 997135..997770 (+) 636 WP_172125612.1 hypothetical protein -
  AACT_RS05225 (AACT_1032) - 997780..999072 (-) 1293 WP_172125614.1 diguanylate cyclase -
  AACT_RS05230 (AACT_1033) - 999229..999708 (-) 480 WP_172128551.1 glutathione peroxidase -
  AACT_RS05235 (AACT_1034) - 999969..1001981 (+) 2013 WP_172125616.1 methyl-accepting chemotaxis protein -

Sequence

Protein


Download         Length: 616 a.a.        Molecular weight: 71687.80 Da        Isoelectric Point: 9.1956

>NTDB_id=378625 AACT_RS05215 WP_172125610.1 995159..997009(-) (uvrC) [Arcobacter acticola strain KCTC 52212]
MNLLEKLKQLPNDAGVYQYFDKDGHLLYIGKAKVLKNRVKSYFKFTPKLLPADKLGPRIYKMISEVVSCEWIVVPNEHDA
LILENSLIKQLKPKYNILLRDDKTYPYIVIDYNQDFPRLEITRRILKEKNVKYFGPYSTGAKDMLDSIYEIVPLVQKKSC
VSGKKACLFHQIQKCLAPCENKISKEDYAKIVETALEYIYNKSKLITKLNERMSQYANNFRFEEAMTLRDRIKTIEKSQI
KSGIDLATNEDIDIFAITASNKKAVVVRMFLRDGKLASSSHDFLKVNNFDENFDFDYNEAYKRAIINYYDNEIPLLPKEI
LTGIELEDVEELEDFLQTRFSKKIKVLNPKKDKKKDIVQIALNNCDELLRIDSSRNQTTIYEELKDLFGLETLPYLIESY
DNSHMMGQATVGAMVVWNEDINAFDKKAFRHYNLESKDEYSQMREMLIRRVENFEKNPAPDLWIIDGGETLLKLAYDIVQ
SVGVNLDIIAVAKEKVDAKAHRAKGAAKDIIHYKTKNGEFKNFKLSTSDKRLQFVQRQRDEAHRFVINFHKKQKRAQDKQ
ISLLQIKGIGEAKIKKLLLYFGEFEKIRNASVEELKNVLNEKDALTIANYFINPKD

Nucleotide


Download         Length: 1851 bp        

>NTDB_id=378625 AACT_RS05215 WP_172125610.1 995159..997009(-) (uvrC) [Arcobacter acticola strain KCTC 52212]
ATGAATCTACTTGAAAAACTCAAACAACTTCCCAATGATGCTGGTGTTTATCAATACTTTGATAAAGATGGACATTTATT
ATATATAGGAAAAGCAAAAGTACTTAAAAATAGAGTTAAATCCTATTTTAAATTTACTCCAAAATTACTACCTGCTGATA
AATTAGGTCCACGAATTTATAAAATGATTTCTGAGGTTGTAAGTTGTGAGTGGATAGTAGTACCAAATGAACATGATGCT
TTGATTTTAGAAAACTCTTTAATCAAACAGCTAAAACCAAAATACAATATTTTACTAAGAGATGATAAAACATATCCATA
TATTGTAATAGATTATAATCAGGATTTTCCAAGACTTGAAATCACAAGAAGAATACTAAAAGAAAAAAATGTAAAGTATT
TTGGACCATATTCAACGGGTGCAAAAGATATGCTAGATAGTATTTATGAAATAGTTCCCCTTGTTCAAAAAAAATCTTGT
GTAAGTGGTAAAAAAGCTTGTCTTTTTCATCAAATACAAAAATGCCTAGCTCCTTGTGAAAATAAAATTTCAAAAGAAGA
TTATGCAAAAATTGTAGAAACTGCCTTAGAATATATCTATAATAAATCAAAATTAATCACAAAATTAAATGAAAGAATGT
CTCAATACGCAAATAATTTTAGATTTGAAGAGGCAATGACTTTAAGAGACAGAATAAAAACAATAGAAAAATCTCAAATC
AAATCAGGTATAGATTTAGCAACAAATGAAGATATAGATATTTTTGCAATAACAGCTTCAAATAAAAAAGCAGTTGTTGT
TAGAATGTTTTTAAGAGATGGAAAACTTGCTTCTTCTTCACATGATTTTTTAAAGGTGAATAACTTTGATGAGAATTTTG
ATTTTGATTATAATGAAGCATATAAAAGAGCTATTATAAACTACTATGACAATGAAATTCCACTTTTACCAAAAGAGATA
TTAACAGGAATTGAACTTGAAGATGTTGAAGAACTAGAAGATTTTTTACAAACAAGATTTTCTAAAAAGATAAAAGTGTT
AAACCCTAAAAAAGATAAGAAAAAGGATATTGTCCAAATTGCTTTAAACAACTGTGATGAACTTTTACGAATTGATTCAA
GTAGAAATCAAACAACAATATATGAAGAGCTAAAAGATTTATTTGGCTTAGAAACACTTCCTTACTTAATAGAAAGTTAT
GATAACTCACATATGATGGGACAAGCAACAGTGGGAGCCATGGTTGTATGGAATGAAGATATAAATGCCTTTGATAAAAA
AGCTTTTAGACACTATAACCTTGAATCAAAAGATGAATACTCTCAAATGAGAGAAATGTTAATAAGAAGGGTTGAAAATT
TTGAAAAAAATCCAGCTCCTGATTTATGGATAATAGATGGTGGAGAAACACTTTTAAAACTAGCCTATGATATCGTGCAA
TCAGTGGGAGTAAATCTTGACATAATTGCAGTTGCCAAAGAAAAAGTTGATGCAAAAGCCCATAGAGCAAAGGGAGCTGC
TAAAGATATCATTCACTATAAAACTAAAAATGGTGAATTTAAAAACTTCAAGTTATCAACAAGTGATAAAAGATTACAAT
TTGTTCAAAGACAAAGAGATGAAGCCCATAGATTCGTAATTAATTTCCATAAAAAACAAAAAAGAGCCCAAGATAAACAA
ATATCACTACTTCAAATAAAAGGCATAGGAGAAGCAAAAATTAAAAAACTTCTTTTATATTTTGGTGAATTTGAGAAAAT
AAGAAATGCATCTGTTGAAGAGTTAAAAAATGTTTTAAATGAAAAAGACGCACTTACTATTGCAAATTATTTTATAAATC
CAAAGGATTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(204-237)

GIY-YIG catalytic domain (GIY-YIG)

(15-96)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(386-547)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6M8EE22

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

51.244

97.89

0.502

Multiple sequence alignment