Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   HB751_RS08365 Genome accession   NZ_CP050272
Coordinates   1711143..1713098 (+) Length   651 a.a.
NCBI ID   WP_019804939.1    Uniprot ID   -
Organism   Streptococcus mutans strain P6     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1706143..1718098
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HB751_RS08340 (HB751_08340) - 1706340..1706825 (+) 486 WP_019804942.1 cyclic nucleotide-binding domain-containing protein -
  HB751_RS08345 (HB751_08345) argR 1707322..1707759 (+) 438 WP_002262400.1 arginine repressor -
  HB751_RS08350 (HB751_08350) - 1707756..1708103 (+) 348 WP_019804941.1 YlbF family regulator -
  HB751_RS08355 (HB751_08355) hexA 1708096..1710645 (+) 2550 WP_019804940.1 DNA mismatch repair protein MutS Machinery gene
  HB751_RS08360 (HB751_08360) - 1710640..1710918 (-) 279 Protein_1617 transposase -
  HB751_RS08365 (HB751_08365) hexB 1711143..1713098 (+) 1956 WP_019804939.1 DNA mismatch repair endonuclease MutL Machinery gene
  HB751_RS08370 (HB751_08370) ruvA 1713283..1713876 (+) 594 WP_002262395.1 Holliday junction branch migration protein RuvA Machinery gene
  HB751_RS08375 (HB751_08375) - 1713958..1714518 (+) 561 WP_002271569.1 DNA-3-methyladenine glycosylase I -
  HB751_RS08380 (HB751_08380) cinA 1714667..1715923 (+) 1257 WP_002266115.1 competence/damage-inducible protein A Machinery gene
  HB751_RS08385 (HB751_08385) recA 1715963..1717114 (+) 1152 WP_002288707.1 recombinase RecA Machinery gene
  HB751_RS08390 (HB751_08390) spx 1717199..1717597 (+) 399 WP_002262391.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 651 a.a.        Molecular weight: 73767.48 Da        Isoelectric Point: 6.4586

>NTDB_id=377899 HB751_RS08365 WP_019804939.1 1711143..1713098(+) (hexB) [Streptococcus mutans strain P6]
MSKIIELPEVLANQIAAGEVIERPASVVKELVENAIDADSSQITIEIEESGLKKIQVTDNGQGIEQADVIMSLRRHATSK
IKKQTDLFRIRTLGFRGEALPSIASISRLTLKTATKGEIYGTLLIANGGKIEKEEAISTPIGTKVSVENLFFNTPARLKY
MKSLQAELAHIIDVINRLSLAHPEIAFTLINDGRELTKTSGKGDLRQALAGIYGVTTAKKMVEISNADLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMNLISS
AIADSLREQELIPDALENLAKTSTNKKQKFEQTQLPLKQSNLCYDKTQNDFFLKETTVSEASSEFTVVDKAVNITDNVSG
HSSVKYAQRQMRTCENKEHPSLTMTNKQQKRQLSRIVESLENEEKSTFPELEYFGQMHGTYLFAQGEGGLYIIDQHAAQE
RVKYEYYRDKIGEVDNSLQQLLVPYLFEFPANDFMTLQEKMSILNEVGVHLENYGENTFILREHPIWLQEKEIESAVYEM
CDMLLLTNEVSIKKYRAELAIMMSCKRSIKANHTLDDYSARNLLIQLSQCKNPYNCPHGRPVLVNFTKADMEKMFRRIQE
NHTSLRELGKY

Nucleotide


Download         Length: 1956 bp        

>NTDB_id=377899 HB751_RS08365 WP_019804939.1 1711143..1713098(+) (hexB) [Streptococcus mutans strain P6]
ATGTCAAAAATTATTGAACTGCCAGAAGTTTTAGCCAATCAAATTGCTGCTGGAGAGGTTATTGAAAGACCAGCTAGTGT
CGTAAAAGAACTAGTTGAGAATGCTATTGACGCTGATAGCAGCCAAATTACAATAGAAATTGAAGAATCAGGACTGAAAA
AAATTCAAGTGACTGATAATGGTCAAGGAATAGAACAAGCGGATGTAATTATGAGCTTACGTCGTCATGCAACTAGTAAG
ATTAAAAAACAAACCGATCTTTTTAGAATTAGGACCTTAGGTTTTAGAGGTGAGGCCCTTCCATCAATTGCTTCTATTAG
CAGACTAACATTAAAAACAGCAACAAAAGGGGAAATATATGGCACTTTATTAATCGCAAATGGAGGTAAAATTGAAAAAG
AAGAAGCCATTAGTACCCCTATTGGAACCAAAGTGAGTGTTGAAAATCTTTTCTTCAATACCCCTGCTCGCCTTAAATAT
ATGAAAAGTTTGCAGGCAGAGCTTGCTCATATTATTGATGTCATTAACCGTCTTAGCTTGGCGCATCCCGAAATTGCTTT
CACGCTTATTAATGATGGCCGTGAATTAACAAAGACGTCAGGTAAAGGCGATCTGCGTCAAGCTTTAGCGGGTATTTATG
GGGTAACCACTGCTAAAAAAATGGTCGAAATTTCAAATGCAGATCTTGATTTTGAGGTATCTGGTTATATTAGTTTGCCT
GAATTAACACGAGCTAATCGCAATTATATTACCATTCTTATTAATGGGCGTTATATCAAAAATTTTTTGCTCAATCGCGC
TATTCTTGATGGTTATGGTTCAAAATTAATGGTGGGACGTTTTCCAATTGCTGTTATTGATATTCAGATTGACCCTTATT
TAGCAGATGTTAATGTTCATCCAACTAAGCAGGAAGTTCGCATTTCTAAAGAAAAAGAGTTAATGAATCTCATTAGTTCG
GCAATTGCAGATAGTTTAAGAGAACAAGAGTTAATTCCTGATGCTTTGGAAAATCTTGCTAAAACTAGCACAAACAAGAA
ACAAAAGTTTGAACAAACACAACTTCCTCTTAAACAATCAAATCTTTGCTATGATAAGACTCAAAATGACTTCTTTCTCA
AAGAAACGACAGTTTCAGAAGCATCAAGCGAGTTTACAGTAGTTGATAAAGCTGTAAATATTACTGATAATGTATCAGGA
CATAGCAGTGTAAAATATGCTCAACGTCAAATGAGAACTTGTGAAAACAAAGAGCATCCAAGTCTTACTATGACAAATAA
GCAACAAAAGCGACAGCTTAGTAGAATTGTTGAAAGTCTAGAAAATGAAGAAAAGTCAACTTTTCCTGAGTTAGAATATT
TTGGTCAAATGCATGGAACTTACCTCTTTGCTCAAGGTGAAGGGGGGCTTTATATCATAGATCAACATGCTGCTCAAGAA
CGTGTTAAATATGAATATTATCGTGATAAAATTGGAGAAGTAGACAATAGTTTACAGCAGCTTTTAGTACCTTATCTTTT
TGAATTTCCTGCTAATGATTTTATGACCTTACAAGAAAAAATGAGCATTTTAAATGAGGTTGGAGTTCACTTAGAAAACT
ATGGAGAGAATACTTTCATTTTGAGAGAACATCCTATTTGGTTACAGGAAAAAGAAATTGAATCAGCCGTTTATGAGATG
TGTGACATGTTGCTGTTGACAAATGAAGTCTCCATTAAGAAATATCGAGCGGAATTAGCTATTATGATGTCTTGCAAGCG
TTCTATCAAGGCTAATCATACTTTGGATGATTATTCTGCCAGAAATCTCTTAATTCAATTATCACAGTGCAAAAATCCTT
ACAACTGTCCTCATGGACGTCCTGTGCTTGTGAATTTCACAAAAGCTGATATGGAAAAGATGTTTCGTCGCATTCAGGAA
AACCATACTAGTTTGAGAGAATTAGGGAAATACTGA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-136)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)

MutL C terminal dimerisation domain (MutL_C)

(453-595)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.909

100

0.707