Detailed information NTG0377691

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: FGL73_RS00530
• Genome accession: NZ_CP042408
• Coordinates: 93055..95505 (+)
• Length: 816 a.a.
• NCBI ID: WP_146977845.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain CBA3619
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 88055..100505

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL73_RS00505 (FGL73_00505)	-	88818..89330 (+)	513	WP_012897343.1	adenine phosphoribosyltransferase	-
FGL73_RS00510 (FGL73_00510)	rpoE	89547..90110 (+)	564	WP_003129551.1	DNA-directed RNA polymerase subunit delta	-
FGL73_RS00515 (FGL73_00515)	mltG	90247..91899 (+)	1653	WP_038599604.1	endolytic transglycosylase MltG	-
FGL73_RS00520 (FGL73_00520)	greA	91960..92433 (+)	474	WP_025016857.1	transcription elongation factor GreA	-
FGL73_RS00525 (FGL73_00525)	-	92610..93065 (+)	456	WP_010905471.1	CtsR family transcriptional regulator	-
FGL73_RS00530 (FGL73_00530)	clpC	93055..95505 (+)	2451	WP_146977845.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
FGL73_RS00535 (FGL73_00535)	hpf	95640..96197 (+)	558	WP_003129564.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
FGL73_RS00540 (FGL73_00540)	eno	96385..97686 (+)	1302	WP_010905473.1	surface-displayed alpha-enolase	-
FGL73_RS00545 (FGL73_00545)	-	97802..98473 (-)	672	WP_058205272.1	ABC transporter ATP-binding protein	-
FGL73_RS00550 (FGL73_00550)	-	98476..99549 (-)	1074	WP_058205271.1	ABC transporter permease	-
FGL73_RS00555 (FGL73_00555)	-	99561..100130 (-)	570	WP_038599617.1	TetR/AcrR family transcriptional regulator	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90409.82 Da
• Isoelectric Point: 6.5300

>NTDB_id=377691 FGL73_RS00530 WP_146977845.1 93055..95505(+) (clpC) [Lactococcus lactis strain CBA3619]
MKFENIKYTPTLDRILEKAEEYAHQYQYGTIESAHLLAAMATTSGSIAYSLLAGMNVDSSDLLIDLEDLSSHVKVKRSTL
RFSPRAEEVMTAASFLAIHNNSEAVGTEHLLYALLQVEDGFGLQLLKLQKINIVSLRKELEKRTGLKVPESKKAVTPMSK
RKMAKGVAENSTTPTLDSVSSDLTEEARLGKLDPMIGREAEIDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSSDPDVIIFIDELHTIIGAGGGMDSVNDAANILKPALAR
GDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDEAIAILQGLREKFEDYHQVKFTDQAIKSAVMLSVRYMTSRK
LPDKAIDLLDEAAAAVKISVKNQQAKRLDLEKELAEAQEELSEAVIKLDIKASRTKEKAVEKIADKIYKFSVKEDKRQEV
TDQAVVAVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGVADSRRPMGSFMFLGPTGVGK
TELAKALADSVFGSEDNMIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHPDVFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATALRDDKTVGFGAKNITADYSAMKSRILEELKRHYRPEFLNRIDENIVF
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAVKLIAEIGFDPEYGARPLRKALQKEVEDLLSEQLLSGEIKAGNH
VSIGASNKKIKIAQIV

Nucleotide

• Length: 2451 bp

>NTDB_id=377691 FGL73_RS00530 WP_146977845.1 93055..95505(+) (clpC) [Lactococcus lactis strain CBA3619]
ATGAAATTTGAAAATATAAAATATACACCAACGCTTGACCGAATTTTAGAAAAAGCGGAAGAGTACGCTCACCAATATCA
ATATGGCACCATTGAAAGTGCACATTTACTGGCTGCAATGGCAACGACCTCAGGCTCAATTGCTTACAGCCTTCTTGCAG
GAATGAATGTTGATTCTTCTGACTTACTAATTGATTTAGAGGATTTATCAAGTCATGTTAAGGTCAAACGTTCAACTTTA
CGTTTTTCACCTCGTGCAGAGGAAGTGATGACTGCGGCAAGTTTTTTAGCAATTCATAATAACTCCGAAGCCGTTGGAAC
AGAACACCTGCTTTATGCCCTACTTCAAGTAGAAGATGGATTTGGTCTTCAACTTCTAAAATTACAAAAAATCAATATTG
TATCTTTGCGAAAAGAGCTTGAGAAAAGAACTGGACTCAAAGTTCCAGAAAGTAAAAAAGCTGTGACTCCAATGTCAAAA
CGCAAGATGGCAAAGGGAGTTGCAGAAAATTCAACGACGCCAACGTTAGACTCTGTATCCTCAGATTTAACCGAAGAAGC
TCGTTTGGGTAAACTTGACCCAATGATTGGACGAGAAGCTGAAATTGACCGTTTGATTCATATTCTCAGCCGCAGAACAA
AAAATAATCCTGTTTTAGTTGGAGAGCCCGGTGTTGGGAAATCAGCAATTATTGAAGGTTTGGCCCAAAGAATTGTCAAT
GGTCAAGTTCCAATTGGTTTGATGAATAGTCGAATTATGGCATTGAATATGGCGACTGTTGTTGCTGGGACAAAATTTAG
AGGTGAATTTGAGGATCGTTTGACAGCTATTGTTGAAGAAGTTAGCAGTGATCCAGATGTCATTATTTTCATTGATGAAT
TACACACAATCATTGGTGCTGGTGGCGGTATGGATTCTGTCAATGATGCCGCAAATATTTTGAAACCAGCGCTTGCTCGT
GGTGATTTTCAAATGGTCGGAGCAACAACCTATCATGAATATCAAAAATATATTGAAAAAGATGAAGCTTTAGAACGCCG
TTTGGCGAGAATAAATGTTGATGAGCCAAGTCCAGATGAAGCGATTGCTATCTTGCAAGGCTTACGTGAAAAATTTGAAG
ACTATCATCAAGTAAAATTTACTGACCAAGCCATTAAAAGTGCTGTAATGCTCAGTGTTCGTTATATGACCAGCAGAAAA
TTGCCTGACAAAGCCATTGATTTACTTGATGAAGCTGCAGCAGCGGTGAAAATTTCTGTCAAAAATCAACAAGCAAAACG
TCTTGATTTAGAAAAAGAACTAGCCGAAGCTCAAGAAGAATTATCAGAAGCTGTCATTAAGCTTGACATCAAAGCGTCTC
GTACAAAAGAAAAAGCAGTTGAAAAAATTGCTGACAAGATTTATAAATTCTCAGTAAAAGAAGATAAACGTCAAGAAGTT
ACTGACCAAGCTGTTGTTGCTGTTGCCTCAACACTGACAGGTGTTCCAATCACACAAATGACTAAGTCTGAAAGTGATCG
TTTAATCAATCTTGAAAAAGAATTACACAAACGAGTTGTTGGACAAGAAGAAGCTATTTCTGCCGTTTCAAGAGCCATTC
GTCGGGCACGTTCCGGTGTTGCTGACAGTCGCCGTCCAATGGGTTCTTTCATGTTCCTTGGACCAACAGGGGTCGGTAAA
ACCGAACTTGCTAAAGCACTGGCTGACAGTGTGTTTGGTAGTGAAGATAATATGATTCGTGTTGACATGAGTGAATTCAT
GGAAAAACATTCAACTTCACGCTTGATTGGAGCTCCTCCAGGGTATGTAGGTTATGATGAGGGTGGACAATTGACAGAAC
GCGTTCGTAATAAACCATATTCTGTTGTTCTTTTAGATGAAGTCGAAAAAGCTCATCCTGACGTTTTCAACATCATGTTG
CAAATTCTAGATGATGGCTTTGTGACTGATACTAAAGGTCGCAAAGTTGATTTCAGAAATACAATTATTATCATGACTTC
AAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACAGTTGGTTTTGGCGCTAAAAATATCACAGCTGATTATTCAGCCA
TGAAATCAAGAATATTAGAAGAGCTTAAACGTCATTATCGTCCTGAGTTTCTTAATCGAATTGATGAAAATATTGTTTTC
CATTCATTGGAAAGTCAAGAGATTGAACAAATTGTTAAAATTATGAGTAAATCTTTGATTAAACGTCTGGCAGAACAAGA
TATTCATGTTAAACTCACACCATCAGCGGTGAAATTAATTGCTGAAATAGGTTTTGACCCAGAATATGGTGCACGTCCTC
TACGTAAGGCACTTCAAAAAGAAGTCGAAGACCTTTTAAGTGAACAACTGCTCTCTGGTGAAATCAAAGCAGGTAATCAT
GTTTCAATTGGTGCATCTAATAAAAAAATTAAAATCGCTCAAATTGTTTGA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (357-453)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-802)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (19-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-144)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-334)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	99.755	100	0.998
clpC	Streptococcus thermophilus LMG 18311	50.903	100	0.518
clpC	Streptococcus thermophilus LMD-9	50.542	100	0.515
clpC	Streptococcus pneumoniae Rx1	48.918	100	0.499
clpC	Streptococcus pneumoniae D39	48.918	100	0.499
clpC	Streptococcus pneumoniae TIGR4	48.798	100	0.498
clpC	Bacillus subtilis subsp. subtilis str. 168	50.499	98.284	0.496
clpC	Streptococcus mutans UA159	48.558	100	0.495
clpE	Streptococcus mutans UA159	47.846	79.657	0.381
clpC	Lactococcus lactis subsp. cremoris KW2	47.023	80.27	0.377
clpE	Streptococcus pneumoniae TIGR4	47.687	76.838	0.366
clpE	Streptococcus pneumoniae Rx1	47.687	76.838	0.366
clpE	Streptococcus pneumoniae D39	47.687	76.838	0.366
clpE	Streptococcus pneumoniae R6	47.687	76.838	0.366