Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   HA248_RS00935 Genome accession   NZ_CP050175
Coordinates   175744..176337 (+) Length   197 a.a.
NCBI ID   WP_000271489.1    Uniprot ID   Q8DRE8
Organism   Streptococcus pneumoniae strain PZ900701590     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 170744..181337
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HA248_RS00915 (HA248_00910) ribE 171926..172393 (-) 468 WP_001099502.1 6,7-dimethyl-8-ribityllumazine synthase -
  HA248_RS00920 (HA248_00915) - 172394..173599 (-) 1206 WP_000456639.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  HA248_RS00925 (HA248_00920) ribE 173619..174254 (-) 636 WP_000493846.1 riboflavin synthase -
  HA248_RS00930 (HA248_00925) ribD 174239..175339 (-) 1101 WP_033707887.1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD -
  HA248_RS00935 (HA248_00930) ruvA 175744..176337 (+) 594 WP_000271489.1 Holliday junction branch migration protein RuvA Machinery gene
  HA248_RS00940 (HA248_00935) - 176347..176910 (+) 564 WP_166735653.1 DNA-3-methyladenine glycosylase I -
  HA248_RS00945 (HA248_00940) - 176907..177584 (+) 678 WP_000987411.1 CPBP family intramembrane glutamic endopeptidase -
  HA248_RS00950 (HA248_00945) - 177739..178770 (-) 1032 WP_044727680.1 S66 peptidase family protein -
  HA248_RS00955 (HA248_00950) - 179025..179708 (-) 684 WP_033705639.1 DUF1129 domain-containing protein -
  HA248_RS00960 (HA248_00955) - 179720..180664 (-) 945 WP_000815629.1 magnesium transporter CorA family protein -

Sequence

Protein


Download         Length: 197 a.a.        Molecular weight: 21548.06 Da        Isoelectric Point: 7.3085

>NTDB_id=377475 HA248_RS00935 WP_000271489.1 175744..176337(+) (ruvA) [Streptococcus pneumoniae strain PZ900701590]
MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEAQIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGI
GPVSALAIIAADDNAGLVQAIETKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK

Nucleotide


Download         Length: 594 bp        

>NTDB_id=377475 HA248_RS00935 WP_000271489.1 175744..176337(+) (ruvA) [Streptococcus pneumoniae strain PZ900701590]
ATGTACGCATATTTAAAAGGAATCATTACCAAAATTACTGCCAAATACATTGTTCTTGAAACCAATGGTATTGGTTATAT
CCTGCATGTGGCCAATCCTTATGCCTATTCAGGTCAGGTTAATCAGGAGGCTCAGATTTATGTGCATCAGGTTGTGCGTG
AGGACGCCCATTTGCTTTATGGATTTCGCTCAGAGGATGAGAAAAAGCTCTTTCTTAGTCTGATTTCGGTCTCTGGGATT
GGTCCTGTATCAGCTCTTGCTATTATCGCTGCTGATGACAATGCTGGCTTGGTTCAAGCCATTGAAACCAAGAACATCAC
CTACTTGACCAAGTTCCCTAAAATTGGCAAGAAAACAGCCCAGCAGATGGTGCTGGACTTGGAAGGCAAGGTAGTAGTTG
CAGGAGATGGCCTTCCTGCCAAGGTCGCAGTGCAAGCAAGTGCTGAAAACCAAGAATTGGAAGAAGCTATGGAAGCCATG
TTGGCTCTGGGCTACAAGGCAACAGAGCTCAAGAAAATCAAGAAATTCTTTGAAGGAACGACAGATACAGCTGAGAACTA
TATCAAGTCGGCCCTTAAAATGTTGGTCAAATAG

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA N terminal domain (RuvA_N)

(1-61)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DRE8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae R6

100

100

1
  ruvA Streptococcus pneumoniae D39

100

100

1
  ruvA Streptococcus pneumoniae TIGR4

99.492

100

0.995
  ruvA Bacillus subtilis subsp. subtilis str. 168

39.806

100

0.416

Multiple sequence alignment