Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   HPSA_RS07280 Genome accession   NC_017361
Coordinates   1530678..1533047 (+) Length   789 a.a.
NCBI ID   WP_234701622.1    Uniprot ID   -
Organism   Helicobacter pylori SouthAfrica7     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1525678..1538047
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPSA_RS07255 (HPSA_07540) - 1527440..1528219 (+) 780 WP_001158479.1 hypothetical protein -
  HPSA_RS07260 (HPSA_07545) - 1528239..1528532 (+) 294 WP_001160325.1 hypothetical protein -
  HPSA_RS07265 (HPSA_07550) - 1528539..1530065 (+) 1527 WP_000323331.1 hypothetical protein -
  HPSA_RS07270 (HPSA_07555) - 1530062..1530364 (+) 303 WP_000850073.1 hypothetical protein -
  HPSA_RS07275 (HPSA_07560) comB3 1530365..1530631 (+) 267 WP_001173700.1 hypothetical protein Machinery gene
  HPSA_RS07280 (HPSA_07565) comB4 1530678..1533047 (+) 2370 WP_234701622.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  HPSA_RS07285 (HPSA_07570) - 1533050..1533925 (+) 876 Protein_1415 DNA topoisomerase -
  HPSA_RS07290 (HPSA_07575) tnpA 1533988..1534404 (-) 417 WP_000717711.1 IS200/IS605 family transposase -
  HPSA_RS07295 (HPSA_07580) - 1534441..1535769 (+) 1329 WP_000867437.1 RNA-guided endonuclease InsQ/TnpB family protein -
  HPSA_RS07305 (HPSA_07585) - 1535829..1537052 (+) 1224 Protein_1418 DNA topoisomerase -

Sequence

Protein


Download         Length: 789 a.a.        Molecular weight: 91221.76 Da        Isoelectric Point: 8.1799

>NTDB_id=37735 HPSA_RS07280 WP_234701622.1 1530678..1533047(+) (comB4) [Helicobacter pylori SouthAfrica7]
MKEETNIVGIYNEHYLLSEKSNLVGALKLEGISYLSLDDKEIGQKFNERILALNEIVDGVHFKIVAKRRKIFMHHEYTQE
EISNPFALEVINLWEQGVEDVYQNFYYLIFETKNDSIKGYLERFKKKITTNELENIQESDKQNEVKYQENYFIGFDNFNL
VDKSKILDSIINNVKSMLSNLFVEKLDANSLLNFYAEYINGVPSEYTFARGRLHDGMINSDVHFKKDFFTHIHNGKEIFK
RFISIKTYDIDKIVSTALSSVLHLSLEFDVILNIDNIPKAKAEKKIETKRKRANKSIRVEIDELNDMVKTDRVLMQEISL
NILVHAKTKTDLDSACIEIANLLKQKGIVNTQESIGMLPMFFSFFPNRNRLNFRKRLLSSQNIASLIILEKQNCGFSRNS
WGNRHLTIFRNQDKSPYLFNFHAYEAKRKDDMVSGHTIIFGGTGAGKTTLIEFLITNCFKYKDLSILALDRNNGMRVMTE
FLDGHYNDSNDFYINPFSLKDTSANCTFLVSWLAFMLNIDEYTKDEKEKKTLSALSKTIRVCYNNITKQGGAIFKLKDFK
DTLERDYLDSKDILEKEGSKDLYKHSTDCLDFAKKLSVIDMDALSNNKKDFHLAVLYLFYKVMNRAKLENKPFYIFIDEA
KSVIENPIMLAKIKDTLAQARKLNGVLTLAFQDINQLDGVEGAKSIVENAAQVILYPTSNFEKLESYGILLSPIEKSFLN
KTPLNARQILVKNLLTQSSVFLEINLEKLNSTNKKFLRAYSSSASSVFELEMLKKDNPRDYKEIYLTKE

Nucleotide


Download         Length: 2370 bp        

>NTDB_id=37735 HPSA_RS07280 WP_234701622.1 1530678..1533047(+) (comB4) [Helicobacter pylori SouthAfrica7]
ATGAAAGAAGAAACTAACATTGTAGGCATTTACAATGAGCATTATCTTTTAAGCGAAAAATCAAACCTTGTGGGTGCTCT
TAAATTAGAGGGAATTTCTTATTTATCTTTAGATGACAAAGAAATAGGGCAAAAATTTAATGAACGCATTTTAGCTCTTA
ATGAGATTGTAGATGGAGTGCATTTTAAAATCGTAGCTAAAAGGCGTAAGATTTTCATGCACCATGAATATACTCAAGAA
GAGATAAGTAATCCTTTTGCATTAGAAGTTATCAATTTATGGGAGCAAGGGGTTGAGGATGTTTATCAAAATTTCTATTA
TTTAATTTTTGAAACTAAGAATGATAGCATTAAAGGTTATTTGGAACGATTTAAGAAAAAAATCACTACCAATGAATTAG
AAAATATTCAAGAAAGTGATAAACAAAATGAAGTTAAATATCAAGAAAACTATTTCATAGGCTTTGATAATTTTAATTTA
GTAGATAAATCTAAAATATTAGACAGCATTATCAATAATGTCAAAAGCATGCTTTCCAATTTGTTTGTAGAAAAATTAGA
CGCCAATAGTTTGCTTAATTTTTATGCGGAATATATCAATGGCGTTCCTAGTGAATACACTTTTGCTAGAGGTCGTTTGC
ATGATGGCATGATCAATTCTGATGTGCATTTTAAAAAAGATTTTTTCACTCACATTCATAATGGTAAAGAGATTTTCAAG
CGTTTCATCAGCATTAAGACTTATGATATAGACAAAATTGTCAGCACTGCTCTTTCTTCAGTGTTGCATTTATCTTTAGA
ATTTGATGTGATTTTAAACATTGACAATATTCCTAAAGCAAAGGCTGAAAAAAAGATTGAAACTAAAAGAAAAAGAGCGA
ATAAGAGTATTAGAGTTGAAATTGATGAATTGAATGACATGGTTAAAACAGACAGAGTTTTAATGCAAGAGATTTCTTTA
AATATTTTAGTTCATGCCAAAACTAAAACCGATTTAGATAGTGCTTGTATAGAAATTGCCAACTTGCTCAAACAAAAAGG
CATTGTAAACACACAAGAAAGTATTGGCATGCTTCCTATGTTTTTTAGCTTCTTCCCCAATCGTAATCGCTTGAATTTTA
GAAAGCGTTTGTTGTCTAGTCAAAATATTGCTTCTTTAATCATATTAGAAAAGCAAAATTGTGGTTTTTCTAGAAATTCA
TGGGGTAACCGCCATTTAACTATTTTTAGAAACCAAGACAAATCGCCTTATTTATTCAATTTCCATGCTTATGAGGCAAA
AAGAAAAGATGATATGGTATCAGGGCATACCATCATCTTTGGTGGCACAGGGGCTGGTAAAACCACTTTAATTGAATTTT
TAATCACTAATTGTTTTAAGTATAAAGATTTAAGTATTTTGGCTTTAGATAGAAATAATGGCATGCGTGTGATGACTGAG
TTTTTAGATGGCCACTACAACGATAGCAATGATTTTTACATTAATCCGTTTTCTTTAAAAGATACAAGCGCTAATTGCAC
CTTTTTAGTGAGTTGGCTAGCGTTCATGCTCAATATTGATGAATATACTAAAGATGAGAAAGAAAAAAAGACTTTAAGTG
CCTTATCTAAAACGATCAGAGTTTGCTATAACAATATCACAAAACAAGGGGGTGCTATTTTTAAGTTAAAGGATTTTAAA
GACACGCTAGAAAGAGACTATTTAGATAGCAAAGACATTTTAGAAAAAGAGGGCTCAAAAGACTTATACAAGCATTCTAC
TGATTGTTTAGACTTTGCCAAAAAGCTTTCCGTTATTGATATGGACGCTCTTTCTAATAATAAAAAAGATTTCCACTTGG
CAGTATTATACCTATTCTATAAAGTCATGAACAGAGCTAAATTAGAAAACAAGCCTTTTTATATATTCATTGATGAAGCA
AAATCTGTTATTGAAAATCCCATCATGTTAGCTAAAATCAAAGACACACTCGCTCAAGCTAGAAAACTCAATGGGGTTTT
AACTTTAGCCTTTCAAGACATTAACCAACTTGATGGTGTAGAGGGAGCAAAGTCCATTGTGGAAAATGCCGCTCAAGTCA
TACTCTATCCTACAAGCAATTTTGAGAAATTAGAGAGCTATGGCATTTTATTAAGTCCTATTGAAAAATCCTTTTTAAAC
AAAACACCATTAAACGCTAGGCAAATATTAGTGAAAAACCTCCTCACTCAATCTAGCGTATTTTTAGAGATTAACTTAGA
AAAGTTAAACAGCACCAATAAAAAATTTTTAAGAGCGTATAGCTCTAGCGCATCTAGCGTTTTTGAACTGGAAATGCTTA
AAAAGGATAATCCAAGAGATTACAAAGAAATTTATTTGACAAAGGAGTAG

Domains

Predicted by InterProScan.

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(177-374)

Helicase HerA, central domain (DUF87)

(430-472)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

35.975

100

0.362

Multiple sequence alignment