Detailed information NTG0377243

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: FSN21_RS13990
• Genome accession: NZ_CP042346
• Coordinates: 2728764..2729651 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain BSN9S
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2723764..2734651

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FSN21_RS13955 (FSN21_13955)	-	2723783..2723875 (+)	93	WP_010956583.1	hypothetical protein	-
FSN21_RS13960 (FSN21_13960)	-	2723983..2724480 (-)	498	WP_001065268.1	glutathione peroxidase	-
FSN21_RS13965 (FSN21_13965)	-	2724490..2724750 (-)	261	WP_001789910.1	hypothetical protein	-
FSN21_RS13975 (FSN21_13975)	-	2725132..2725245 (-)	114	WP_001791776.1	hypothetical protein	-
FSN21_RS13980 (FSN21_13980)	-	2725904..2727904 (-)	2001	WP_000776751.1	ABC transporter permease	-
FSN21_RS13985 (FSN21_13985)	-	2727901..2728656 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
FSN21_RS13990 (FSN21_13990)	braS	2728764..2729651 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
FSN21_RS13995 (FSN21_13995)	braR	2729662..2730327 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
FSN21_RS14000 (FSN21_14000)	-	2730353..2730553 (-)	201	WP_000604728.1	hypothetical protein	-
FSN21_RS14005 (FSN21_14005)	-	2730751..2732175 (+)	1425	WP_000953744.1	alkaline phosphatase	-
FSN21_RS14905 (FSN21_14010)	-	2732235..2732336 (-)	102	WP_000731972.1	SE2200 family small protein	-
FSN21_RS14015 (FSN21_14015)	-	2732458..2732913 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
FSN21_RS14020 (FSN21_14020)	-	2733158..2733919 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=377243 FSN21_RS13990 WP_000143419.1 2728764..2729651(-) (braS) [Staphylococcus aureus strain BSN9S]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=377243 FSN21_RS13990 WP_000143419.1 2728764..2729651(-) (braS) [Staphylococcus aureus strain BSN9S]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997