Detailed information NTG0377238

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: FSN21_RS09980
• Genome accession: NZ_CP042346
• Coordinates: 1986331..1987374 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN9S
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1981331..1992374

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FSN21_RS09950 (FSN21_09950)	-	1981749..1983005 (-)	1257	WP_001795438.1	aminopeptidase	-
FSN21_RS09955 (FSN21_09955)	-	1983008..1983208 (-)	201	WP_000180461.1	DUF1128 family protein	-
FSN21_RS09960 (FSN21_09960)	-	1983355..1983819 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
FSN21_RS09965 (FSN21_09965)	-	1983826..1984101 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
FSN21_RS09970 (FSN21_09970)	-	1984379..1985596 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
FSN21_RS09975 (FSN21_09975)	vraR	1985712..1986341 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
FSN21_RS09980 (FSN21_09980)	vraS	1986331..1987374 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
FSN21_RS09985 (FSN21_09985)	liaF	1987371..1988072 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
FSN21_RS09990 (FSN21_09990)	-	1988087..1988473 (-)	387	WP_001110179.1	hypothetical protein	-
FSN21_RS09995 (FSN21_09995)	map	1988690..1989448 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
FSN21_RS10000 (FSN21_10000)	-	1989976..1990962 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
FSN21_RS10010 (FSN21_10010)	-	1991452..1991865 (-)	414	WP_001549145.1	hypothetical protein	-
FSN21_RS10015 (FSN21_10015)	-	1991894..1992004 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=377238 FSN21_RS09980 WP_001017131.1 1986331..1987374(-) (vraS) [Staphylococcus aureus strain BSN9S]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=377238 FSN21_RS09980 WP_001017131.1 1986331..1987374(-) (vraS) [Staphylococcus aureus strain BSN9S]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1