Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   FPV14_RS10575 Genome accession   NZ_CP042286
Coordinates   2203312..2204028 (+) Length   238 a.a.
NCBI ID   WP_000688486.1    Uniprot ID   A0A7U7PWL0
Organism   Staphylococcus argenteus strain B3-25B     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2198312..2209028
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FPV14_RS10545 (FPV14_10545) - 2198869..2199495 (+) 627 WP_047557362.1 nitroreductase family protein -
  FPV14_RS10550 (FPV14_10550) - 2199596..2200381 (+) 786 WP_047557364.1 carbon-nitrogen family hydrolase -
  FPV14_RS13355 hld 2200901..2200981 (-) 81 WP_000046023.1 delta-hemolysin -
  FPV14_RS10560 (FPV14_10560) - 2201271..2201834 (+) 564 WP_047557369.1 accessory gene regulator AgrB -
  FPV14_RS10565 (FPV14_10565) agrD 2201836..2201976 (+) 141 WP_047432494.1 cyclic lactone autoinducer peptide AgrD -
  FPV14_RS10570 (FPV14_10570) agrC 2202001..2203293 (+) 1293 WP_047432499.1 quorum-sensing sensor histidine kinase AgrC -
  FPV14_RS10575 (FPV14_10575) agrA 2203312..2204028 (+) 717 WP_000688486.1 quorum-sensing response regulator AgrA Regulator
  FPV14_RS10580 (FPV14_10580) - 2204381..2205340 (-) 960 WP_047557373.1 carbohydrate kinase -
  FPV14_RS10585 (FPV14_10585) - 2205337..2206821 (-) 1485 WP_047557375.1 sucrose-6-phosphate hydrolase -
  FPV14_RS10590 (FPV14_10590) - 2206970..2207920 (-) 951 WP_000790316.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27894.87 Da        Isoelectric Point: 5.8625

>NTDB_id=376640 FPV14_RS10575 WP_000688486.1 2203312..2204028(+) (agrA) [Staphylococcus argenteus strain B3-25B]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDDPYEVLEQSKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELKTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=376640 FPV14_RS10575 WP_000688486.1 2203312..2204028(+) (agrA) [Staphylococcus argenteus strain B3-25B]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAACCTATGGAAATTGCCCTCGCAACTGATGATCCTTATGAGGTGCTTGAGCAATCTAAAAATATGAATGATATAG
GTTGTTACTTTTTAGATATTCAACTTTCAACAGACATTAATGGTATTAAATTAGGTAGTGAAATACGTAAGCATGACCCT
GTTGGCAATATAATATTTGTTACTAGTCATAGTGAACTTACTTATTTAACATTTGTCTACAAAGTTGCAGCAATGGATTT
TATTTTTAAAGATGATCCTGCTGAATTAAAAACACGAATTATAGATTGTCTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATAGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATACGATGATATTATG
TTTTTCGAATCATCTACCAAATCGCATAGACTCATCGCCCATTTAGATAATCGTCAAATTGAATTTTATGGTAATTTAAA
AGAATTGAGTCAATTAGATGATCGTTTTTTCAGATGTCATAATAGTTTTGTTGTCAATCGTCATAATATCGAATCCATTG
ATTCGAAAGAACGAATTGTCTATTTTAAAAATAAAGAACATTGTTATGCATCGGTAAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7PWL0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

98.739

100

0.987

Multiple sequence alignment