Detailed information NTG0376639

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: FPV14_RS10225
• Genome accession: NZ_CP042286
• Coordinates: 2130134..2131177 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus argenteus strain B3-25B
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2125134..2136177

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FPV14_RS10195 (FPV14_10195)	-	2125545..2126792 (-)	1248	WP_047557219.1	aminopeptidase	-
FPV14_RS10200 (FPV14_10200)	-	2126804..2127004 (-)	201	WP_000180459.1	DUF1128 family protein	-
FPV14_RS10205 (FPV14_10205)	-	2127151..2127615 (+)	465	WP_000228669.1	low molecular weight protein-tyrosine-phosphatase	-
FPV14_RS10210 (FPV14_10210)	-	2127622..2127897 (+)	276	WP_047557221.1	YtxH domain-containing protein	-
FPV14_RS10215 (FPV14_10215)	-	2128176..2129399 (+)	1224	WP_047557224.1	YihY/virulence factor BrkB family protein	-
FPV14_RS10220 (FPV14_10220)	vraR	2129515..2130144 (-)	630	WP_000153529.1	two-component system response regulator VraR	Regulator
FPV14_RS10225 (FPV14_10225)	vraS	2130134..2131177 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
FPV14_RS10230 (FPV14_10230)	liaF	2131174..2131875 (-)	702	WP_000149061.1	cell wall-active antibiotics response protein LiaF	-
FPV14_RS10235 (FPV14_10235)	-	2131890..2132276 (-)	387	WP_001110170.1	hypothetical protein	-
FPV14_RS10240 (FPV14_10240)	map	2132497..2133255 (-)	759	WP_031788218.1	type I methionyl aminopeptidase	-
FPV14_RS10245 (FPV14_10245)	-	2133779..2134765 (+)	987	WP_047557232.1	aromatic acid exporter family protein	-
FPV14_RS10250 (FPV14_10250)	-	2135167..2135547 (-)	381	WP_225995457.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=376639 FPV14_RS10225 WP_001017131.1 2130134..2131177(-) (vraS) [Staphylococcus argenteus strain B3-25B]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=376639 FPV14_RS10225 WP_001017131.1 2130134..2131177(-) (vraS) [Staphylococcus argenteus strain B3-25B]
ATGAACCATTATATTAGAACAATTGGTTCGATGCTCATCTTAGTATACAGCATGCTAGCGGCATTTCTTTTTATAGATAA
AGTTTTCGTTAATATTATTTATTTTCAAGGCATGTTTTATACACAAATATTTGGGATTCCAGTCTTTTTATTTTTAAATC
TCATTATCATTTTATTGTGTATCATCGTCGGATCGGTGCTTGCCTACAAAATTAATCAACAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCTATGGAAGGCGAAACAGTAGGTATCAATGATCAAAATATAGAAATATATAGTGAAACATTAGATTT
ATATCATACGTTAGTACCTTTAAATCAAGAATTGCATAAGTTAAGACTCAAAACGCAAAATTTAACAAATGAAAATTACA
ATATTAATGATGTTAAAGTTAAAAAGATTATCGAAGATGAAAGACAACGTTTAGCTAGAGAACTACACGACTCTGTTAGT
CAACAACTTTTTGCGGCAAGTATGATGTTATCTGCAATTAAAGAAACGAAATTAGAACCACCTTTAGATCAACAAATACC
TATTTTAGAGAAAATGGTTCAAGATTCTCAGTTAGAAATGCGTGCTCTGCTGTTACACTTAAGACCACTCGGCTTGAAAG
ATAAGTCGTTAGGCGAAGGTATTAAAGATTTAGTTATTGATTTACAAAAGAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCGAAAGGTATTGAGGATCATTTATTTAGAATTACGCAAGAAGCAATATCTAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTAGAATTATTTAATAAAGATGATTATTTATTGTTAAGGATACAAGATAATGGTAAAG
GTTTTAATGTAGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCACTACCAGATTCAGGTACACGTATTGAGGTGAAAGCACCTCTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1