Detailed information NTG0037630

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: HMPREF0837_RS10150
• Genome accession: NC_014251
• Coordinates: 1936895..1937962 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159553.1
• Uniprot ID: A0A0T8CF10
• Organism: Streptococcus pneumoniae TCH8431/19A
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1931895..1942962

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF0837_RS10115 (HMPREF0837_12110)	treR	1931982..1932692 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
HMPREF0837_RS12505	-	1932849..1933992 (+)	1144	Protein_1931	transposase	-
HMPREF0837_RS10135 (HMPREF0837_12114)	-	1934159..1935505 (+)	1347	WP_001814919.1	IS1380-like element ISSpn5 family transposase	-
HMPREF0837_RS10140 (HMPREF0837_12115)	-	1935698..1935883 (+)	186	Protein_1933	transposase	-
HMPREF0837_RS10145 (HMPREF0837_12116)	amiF	1935958..1936884 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
HMPREF0837_RS10150 (HMPREF0837_12117)	amiE	1936895..1937962 (-)	1068	WP_000159553.1	ABC transporter ATP-binding protein	Regulator
HMPREF0837_RS10155 (HMPREF0837_12118)	amiD	1937971..1938897 (-)	927	WP_000103702.1	oligopeptide ABC transporter permease OppC	Regulator
HMPREF0837_RS10160 (HMPREF0837_12119)	amiC	1938897..1940393 (-)	1497	WP_000759905.1	ABC transporter permease	Regulator
HMPREF0837_RS10165 (HMPREF0837_12120)	amiA3	1940460..1942439 (-)	1980	WP_000742234.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39437.04 Da
• Isoelectric Point: 4.8002

>NTDB_id=37630 HMPREF0837_RS10150 WP_000159553.1 1936895..1937962(-) (amiE) [Streptococcus pneumoniae TCH8431/19A]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPCHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=37630 HMPREF0837_RS10150 WP_000159553.1 1936895..1937962(-) (amiE) [Streptococcus pneumoniae TCH8431/19A]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTTGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: A0A0T8CF10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.451	100	0.885
amiE	Streptococcus thermophilus LMG 18311	86.761	100	0.868
amiE	Streptococcus thermophilus LMD-9	86.761	100	0.868
oppD	Streptococcus mutans UA159	54.545	99.155	0.541