Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   HMPREF0837_RS08650 Genome accession   NC_014251
Coordinates   1661441..1662673 (-) Length   410 a.a.
NCBI ID   WP_001814787.1    Uniprot ID   -
Organism   Streptococcus pneumoniae TCH8431/19A     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1656441..1667673
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF0837_RS08620 (HMPREF0837_11799) - 1656628..1657596 (+) 969 WP_000081004.1 NAD(P)/FAD-dependent oxidoreductase -
  HMPREF0837_RS08625 (HMPREF0837_11800) whiA 1657630..1658541 (-) 912 WP_000011306.1 DNA-binding protein WhiA -
  HMPREF0837_RS08630 (HMPREF0837_11801) - 1658538..1659515 (-) 978 WP_001231086.1 YvcK family protein -
  HMPREF0837_RS08635 (HMPREF0837_11802) rapZ 1659512..1660402 (-) 891 WP_000163033.1 RNase adapter RapZ -
  HMPREF0837_RS08640 (HMPREF0837_11803) - 1660454..1660834 (-) 381 WP_001140412.1 RidA family protein -
  HMPREF0837_RS08645 (HMPREF0837_11804) yihA 1660845..1661432 (-) 588 WP_000422599.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  HMPREF0837_RS08650 (HMPREF0837_11805) clpX 1661441..1662673 (-) 1233 WP_001814787.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  HMPREF0837_RS08655 (HMPREF0837_11806) - 1662710..1662880 (-) 171 WP_000442260.1 hypothetical protein -
  HMPREF0837_RS08660 (HMPREF0837_11807) - 1662880..1663386 (-) 507 WP_000162475.1 dihydrofolate reductase -
  HMPREF0837_RS08665 (HMPREF0837_11808) - 1663518..1664036 (-) 519 WP_000229868.1 DNA starvation/stationary phase protection protein -
  HMPREF0837_RS08670 (HMPREF0837_11809) lytC 1664533..1666038 (-) 1506 WP_013193470.1 choline binding-anchored murein hydrolase LytC -
  HMPREF0837_RS08675 (HMPREF0837_11810) tpiA 1666076..1666834 (-) 759 WP_000087897.1 triose-phosphate isomerase -
  HMPREF0837_RS08680 (HMPREF0837_11811) - 1666933..1667610 (-) 678 WP_000221584.1 DnaD domain-containing protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45725.30 Da        Isoelectric Point: 4.4775

>NTDB_id=37621 HMPREF0837_RS08650 WP_001814787.1 1661441..1662673(-) (clpX) [Streptococcus pneumoniae TCH8431/19A]
MPTTRNNDMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELKFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=37621 HMPREF0837_RS08650 WP_001814787.1 1661441..1662673(-) (clpX) [Streptococcus pneumoniae TCH8431/19A]
ATGCCTACAACTAGGAATAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAGCCAAGAAGAAGTACAAAAAATAAT
CGCAGGGAACAACGCCTTTATCTGTAATGAATGTGTGGAGTTAGCCCAGGAAATCATTCGTGAGGAGTTGGCTGAGGAAG
TTTTGGCAGACTTGTCTGAAGTTCCAAAACCAATCGAACTTCTCCATATCTTGAACCACTATGTAATCGGTCAAGATCGT
GCCAAACGGGCCTTAGCAGTGGCGGTTTACAACCACTACAAACGCATCAATTTCCACGATACGCGTGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATCTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCTCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGATGTGGAAAAT
ATCCTTCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTGCCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGAAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATTATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.098

100

0.861
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.463

98.049

0.563

Multiple sequence alignment