Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   HMPREF0837_RS06120 Genome accession   NC_014251
Coordinates   1173530..1174339 (+) Length   269 a.a.
NCBI ID   WP_001289493.1    Uniprot ID   Q9RCS5
Organism   Streptococcus pneumoniae TCH8431/19A     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1168530..1179339
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF0837_RS06105 (HMPREF0837_11274) mutY 1170252..1171427 (+) 1176 WP_000886147.1 A/G-specific adenine glycosylase -
  HMPREF0837_RS06110 (HMPREF0837_11275) micA 1171482..1172186 (+) 705 WP_000722076.1 response regulator YycF Regulator
  HMPREF0837_RS06115 (HMPREF0837_11276) micB 1172179..1173528 (+) 1350 WP_000886210.1 cell wall metabolism sensor histidine kinase VicK Regulator
  HMPREF0837_RS06120 (HMPREF0837_11277) vicX 1173530..1174339 (+) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  HMPREF0837_RS06125 (HMPREF0837_11278) relB 1174430..1174672 (+) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  HMPREF0837_RS06130 (HMPREF0837_11279) - 1174674..1174928 (+) 255 WP_001812387.1 type II toxin-antitoxin system RelE/ParE family toxin -
  HMPREF0837_RS06135 (HMPREF0837_11280) - 1174975..1175748 (+) 774 WP_000731129.1 potassium channel family protein -
  HMPREF0837_RS06140 (HMPREF0837_11281) - 1176064..1177410 (-) 1347 WP_001814919.1 IS1380-like element ISSpn5 family transposase -
  HMPREF0837_RS06145 (HMPREF0837_11282) - 1177719..1178705 (-) 987 WP_000204727.1 L-lactate dehydrogenase -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 29916.89 Da        Isoelectric Point: 6.1743

>NTDB_id=37609 HMPREF0837_RS06120 WP_001289493.1 1173530..1174339(+) (vicX) [Streptococcus pneumoniae TCH8431/19A]
MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMD
LYANEKTWQAMENSKYLGKVDSSQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVN
QLAQADLGVGVDFKVYDTSPDTATPLTEI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=37609 HMPREF0837_RS06120 WP_001289493.1 1173530..1174339(+) (vicX) [Streptococcus pneumoniae TCH8431/19A]
ATGAGTGAAATAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCTTTTTATCTGGAAACCTCAAAAAA
GAAGCTTTTAGTAGATGCAGGCTTGTCTGGCAAGAAAATTACCAGTCTGCTAGCTGAAATTAACCGTAAGCCAGAAGACC
TGGATGCCATCTTGATTACCCATGAGCATTCAGATCATATCCATGGAGTAGGCGTTTTGGCTCGCAAGTATGGTATGGAT
CTTTATGCCAATGAAAAGACCTGGCAAGCTATGGAAAATAGTAAATATCTTGGCAAGGTGGATTCTTCGCAAAAGCATAT
TTTTGAAATGGGTAAAACCAAAACCTTTGGAGATATCGACATCGAGAGTTTTGGTGTAAGCCATGATGCAGTCGCACCGC
AGTTCTATCGCTTTATGAAGGATGATAAGAGTTTTGTCCTTTTGACAGATACAGGTTATGTCAGTGACCGTATGGCGGGC
ATTGTCGAAAATGCGGATGGCTATCTTATCGAGGCCAACCATGATGTAGAGATTTTGCGATCAGGTTCTTACGCTTGGCG
ACTCAAACAACGAATCCTATCTGACCTTGGTCACCTTTCTAACGAGGACGGTGCTGAAGCTATGATTCGGACGCTAGGAA
ATCGTACTAAGAAGATTTACCTTGGGCATTTATCTAAGGAAAACAATATCAAGGAACTGGCTCATATGACCATGGTCAAT
CAGCTGGCTCAAGCTGATCTGGGAGTCGGAGTAGACTTTAAGGTTTATGATACCTCACCAGATACCGCAACACCATTGAC
AGAGATATAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9RCS5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

77.323

100

0.773

Multiple sequence alignment