Detailed information NTG0376000

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: D5R83_RS05880
• Genome accession: NZ_CP042211
• Coordinates: 1203459..1204259 (-)
• Length: 266 a.a.
• NCBI ID: WP_000835251.1
• Uniprot ID: D7FF31
• Organism: Helicobacter pylori strain B128 7.13
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1198459..1209259

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D5R83_RS05850 (D5R83_05850)	recJ	1198809..1200359 (+)	1551	WP_000810776.1	single-stranded-DNA-specific exonuclease RecJ	-
D5R83_RS05855 (D5R83_05855)	-	1200359..1201255 (+)	897	WP_001117136.1	RluA family pseudouridine synthase	-
D5R83_RS05860 (D5R83_05860)	-	1201388..1201948 (-)	561	WP_000037134.1	hypothetical protein	-
D5R83_RS05865 (D5R83_05865)	-	1201932..1202270 (-)	339	WP_000699916.1	hypothetical protein	-
D5R83_RS05870 (D5R83_05870)	-	1202458..1202931 (-)	474	WP_013195909.1	tetratricopeptide repeat protein	-
D5R83_RS05875 (D5R83_05875)	dprB	1203058..1203462 (-)	405	WP_000599159.1	Holliday junction resolvase RuvX	Machinery gene
D5R83_RS05880 (D5R83_05880)	dprA	1203459..1204259 (-)	801	WP_000835251.1	DNA-processing protein DprA	Machinery gene
D5R83_RS05885 (D5R83_05885)	minE	1204266..1204499 (-)	234	WP_000051414.1	cell division topological specificity factor MinE	-
D5R83_RS05890 (D5R83_05890)	minD	1204496..1205302 (-)	807	WP_001019050.1	septum site-determining protein MinD	-
D5R83_RS05895 (D5R83_05895)	ilvC	1205326..1206318 (-)	993	WP_001207748.1	ketol-acid reductoisomerase	-
D5R83_RS05905 (D5R83_05905)	-	1206567..1207349 (+)	783	WP_001168242.1	NAD+ synthase	-
D5R83_RS05910 (D5R83_05910)	-	1207346..1208284 (+)	939	WP_000833945.1	tetraacyldisaccharide 4'-kinase	-
D5R83_RS05915 (D5R83_05915)	pseH	1208217..1208759 (-)	543	WP_000742654.1	UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase	-

Sequence

Protein

• Length: 266 a.a.
• Molecular weight: 29879.74 Da
• Isoelectric Point: 6.9617

>NTDB_id=376000 D5R83_RS05880 WP_000835251.1 1203459..1204259(-) (dprA) [Helicobacter pylori strain B128 7.13]
MKSHFQYSVLENIPKAFDILKDPPKQLYCVGDIKLLEAPLKVAIIGTRRPTPYSKQHTITLARELAKNGAVIVSGGALGV
DIIAQENALPTTIMLSPCSLDFIYPTNNHKVIQEIAQNGLILSEYEKDFMPIKGSFLARNRLVIALSDAVIIPQADLKSG
SMSSARLAQKYQKPLFVLPQRLNESDGTNELLEKGQAQGIFNIQNFINTLLKDYHLKEMPEMEDEFLEYCAKNPSYEEAY
LKFGDKLLEYELLGKIKRINHIVVLA

Nucleotide

• Length: 801 bp

>NTDB_id=376000 D5R83_RS05880 WP_000835251.1 1203459..1204259(-) (dprA) [Helicobacter pylori strain B128 7.13]
ATGAAAAGCCATTTCCAATACAGCGTACTAGAAAATATCCCTAAAGCCTTTGACATACTCAAAGACCCTCCTAAACAGCT
CTATTGTGTGGGCGATATAAAGCTTTTAGAAGCGCCTTTAAAAGTGGCGATCATAGGCACAAGAAGACCCACCCCTTATA
GCAAGCAACACACCATCACTCTAGCCAGAGAGCTTGCTAAAAATGGCGCGGTTATTGTGAGCGGGGGAGCGTTAGGCGTG
GATATTATCGCTCAAGAAAACGCCTTACCAACAACGATCATGCTTTCGCCTTGCAGTTTGGATTTTATCTATCCTACGAA
CAATCATAAAGTGATCCAAGAAATCGCGCAAAACGGCTTGATTTTAAGCGAATATGAAAAGGATTTTATGCCCATTAAAG
GCTCTTTTTTAGCCAGAAACCGCCTGGTGATCGCTTTAAGCGATGCGGTGATTATCCCCCAAGCGGATTTAAAAAGCGGC
TCTATGAGTAGCGCGAGATTAGCCCAAAAATACCAAAAACCCTTGTTTGTTTTACCCCAACGCCTGAATGAAAGCGATGG
CACTAATGAGCTTTTAGAAAAAGGGCAGGCTCAAGGGATATTTAATATTCAAAATTTTATAAACACCCTTTTAAAAGACT
ACCATTTAAAAGAAATGCCTGAAATGGAAGATGAATTTTTAGAATATTGTGCGAAAAACCCTAGCTATGAAGAGGCGTAT
CTCAAATTTGGGGATAAGCTTTTAGAATACGAGCTGTTGGGTAAGATTAAACGCATCAATCATATCGTGGTGTTAGCGTG
A

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (13-197)

3D structure

• AlphaFold DB: D7FF31

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Helicobacter pylori 26695	97.368	100	0.974
dprA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	48.673	84.962	0.414