Detailed information NTG0375557

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: FP480_RS05020
• Genome accession: NZ_CP042003
• Coordinates: 1025292..1026335 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain B3-14B
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1020292..1031335

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FP480_RS04990 (FP480_04990)	-	1020907..1021017 (+)	111	WP_014937049.1	hypothetical protein	-
FP480_RS04995 (FP480_04995)	-	1021046..1021459 (+)	414	WP_025174370.1	hypothetical protein	-
FP480_RS05000 (FP480_05000)	-	1021648..1022634 (-)	987	WP_000999712.1	aromatic acid exporter family protein	-
FP480_RS05005 (FP480_05005)	map	1023218..1023976 (+)	759	WP_000636145.1	type I methionyl aminopeptidase	-
FP480_RS05010 (FP480_05010)	-	1024193..1024579 (+)	387	WP_001110182.1	hypothetical protein	-
FP480_RS05015 (FP480_05015)	liaF	1024594..1025295 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
FP480_RS05020 (FP480_05020)	vraS	1025292..1026335 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
FP480_RS05025 (FP480_05025)	vraR	1026325..1026954 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
FP480_RS05030 (FP480_05030)	-	1027067..1028284 (-)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
FP480_RS05035 (FP480_05035)	-	1028562..1028837 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
FP480_RS05040 (FP480_05040)	-	1028844..1029308 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
FP480_RS05045 (FP480_05045)	-	1029455..1029655 (+)	201	WP_000180460.1	DUF1128 family protein	-
FP480_RS05050 (FP480_05050)	-	1029658..1030914 (+)	1257	WP_145411521.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=375557 FP480_RS05020 WP_001017131.1 1025292..1026335(+) (vraS) [Staphylococcus aureus strain B3-14B]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=375557 FP480_RS05020 WP_001017131.1 1025292..1026335(+) (vraS) [Staphylococcus aureus strain B3-14B]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1