Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   FP480_RS04630 Genome accession   NZ_CP042003
Coordinates   950609..951325 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain B3-14B     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 945609..956325
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FP480_RS04615 (FP480_04615) - 946696..947646 (+) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -
  FP480_RS04620 (FP480_04620) - 947795..949279 (+) 1485 WP_000141407.1 sucrose-6-phosphate hydrolase -
  FP480_RS04625 (FP480_04625) - 949276..950235 (+) 960 WP_001253294.1 carbohydrate kinase -
  FP480_RS04630 (FP480_04630) agrA 950609..951325 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  FP480_RS04635 (FP480_04635) agrC 951344..952636 (-) 1293 WP_186364822.1 quorum-sensing sensor histidine kinase AgrC -
  FP480_RS04640 (FP480_04640) agrD 952661..952801 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  FP480_RS04645 (FP480_04645) agrB 952798..953367 (-) 570 WP_001105708.1 accessory gene regulator AgrB -
  FP480_RS15060 hld 953657..953737 (+) 81 WP_000046022.1 delta-hemolysin -
  FP480_RS04655 (FP480_04655) - 954339..955124 (-) 786 WP_000867947.1 carbon-nitrogen family hydrolase -
  FP480_RS04660 (FP480_04660) - 955432..956058 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=375556 FP480_RS04630 WP_000688492.1 950609..951325(-) (agrA) [Staphylococcus aureus strain B3-14B]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=375556 FP480_RS04630 WP_000688492.1 950609..951325(-) (agrA) [Staphylococcus aureus strain B3-14B]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment