Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   G7052_RS08265 Genome accession   NZ_CP049799
Coordinates   1699637..1700299 (-) Length   220 a.a.
NCBI ID   WP_136110879.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 1040     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1694637..1705299
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G7052_RS08240 (G7052_08240) - 1694973..1695221 (-) 249 WP_010922432.1 serine hydrolase -
  G7052_RS08245 (G7052_08245) - 1695206..1695433 (-) 228 WP_030126413.1 hypothetical protein -
  G7052_RS08250 (G7052_08250) sodA 1695600..1696205 (-) 606 WP_002983977.1 superoxide dismutase SodA -
  G7052_RS08255 (G7052_08255) holA 1696302..1697342 (-) 1041 WP_111689533.1 DNA polymerase III subunit delta -
  G7052_RS08260 (G7052_08260) comEC/celB 1697413..1699656 (-) 2244 WP_136274012.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  G7052_RS08265 (G7052_08265) comEA/celA/cilE 1699637..1700299 (-) 663 WP_136110879.1 ComEA family DNA-binding protein Machinery gene
  G7052_RS08270 (G7052_08270) - 1700499..1701239 (-) 741 WP_011054661.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  G7052_RS08275 (G7052_08275) - 1701357..1702133 (+) 777 WP_010922438.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  G7052_RS08280 (G7052_08280) - 1702123..1702401 (+) 279 WP_002989164.1 GIY-YIG nuclease family protein -
  G7052_RS08285 (G7052_08285) - 1702425..1704425 (-) 2001 WP_010922439.1 potassium transporter Kup -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24634.43 Da        Isoelectric Point: 6.7451

>NTDB_id=375307 G7052_RS08265 WP_136110879.1 1699637..1700299(-) (comEA/celA/cilE) [Streptococcus pyogenes strain 1040]
MLDELLIKGKSFLRERYFPPYLISLLLGLFLILSFSFLFWGNRQSKAAVPALREISPVKQQVSEEKKEIQEDNSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETANKDQSKVH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=375307 G7052_RS08265 WP_136110879.1 1699637..1700299(-) (comEA/celA/cilE) [Streptococcus pyogenes strain 1040]
ATGTTAGATGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTCCGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATACTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTGCTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAACAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACATGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGGTCATTAGTTTCTGGTAAAAAAGAAACTGCCAACAAGGATCAGTCAAAGGTTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAGTTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAAAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(156-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.512

94.091

0.4

Multiple sequence alignment