Detailed information NTG0375244

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: FPT06_RS07885
• Genome accession: NZ_CP041994
• Coordinates: 1553214..1554263 (+)
• Length: 349 a.a.
• NCBI ID: WP_004194592.1
• Uniprot ID: A0A0N0DPM5
• Organism: Streptococcus suis strain INT-01
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1548214..1559263

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FPT06_RS07850 (FPT06_07850)	-	1548535..1549629 (+)	1095	WP_004194740.1	sensor histidine kinase	-
FPT06_RS07855 (FPT06_07855)	-	1549626..1550228 (+)	603	WP_004194738.1	response regulator transcription factor	-
FPT06_RS07860 (FPT06_07860)	-	1550528..1550746 (+)	219	WP_004194736.1	YqgQ family protein	-
FPT06_RS07865 (FPT06_07865)	-	1550746..1551132 (+)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
FPT06_RS07870 (FPT06_07870)	-	1551189..1551911 (+)	723	WP_013730502.1	hypothetical protein	-
FPT06_RS07875 (FPT06_07875)	rsmD	1552210..1552749 (+)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
FPT06_RS07880 (FPT06_07880)	coaD	1552739..1553227 (+)	489	WP_002939048.1	pantetheine-phosphate adenylyltransferase	-
FPT06_RS07885 (FPT06_07885)	sepM	1553214..1554263 (+)	1050	WP_004194592.1	SepM family pheromone-processing serine protease	Regulator
FPT06_RS07890 (FPT06_07890)	-	1554451..1555092 (+)	642	WP_004194595.1	YutD-like domain-containing protein	-
FPT06_RS07895 (FPT06_07895)	rlmN	1555101..1556213 (+)	1113	WP_004194597.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
FPT06_RS07900 (FPT06_07900)	-	1556210..1556737 (+)	528	WP_004194600.1	VanZ family protein	-
FPT06_RS07905 (FPT06_07905)	nadE	1557611..1558435 (-)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37747.80 Da
• Isoelectric Point: 4.6112

>NTDB_id=375244 FPT06_RS07885 WP_004194592.1 1553214..1554263(+) (sepM) [Streptococcus suis strain INT-01]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSVPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=375244 FPT06_RS07885 WP_004194592.1 1553214..1554263(+) (sepM) [Streptococcus suis strain INT-01]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAAACTTCGCAAAATATGGCGAAGTATCAAGGATTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTATCTAATGGCAAAAACGGAATAGGCATCACTCTCGTAG
ACCATACAGAGGTTCAAAGTTCGGTTCCAATTGATTTCCAAACGGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGAATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTTATTTCGGCAGCTAAGTCAGGTGCAAGTATTTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAACCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACGAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A0N0DPM5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605