Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR/comR2   Type   Regulator
Locus tag   FPL13_RS00260 Genome accession   NZ_CP041968
Coordinates   37345..37818 (+) Length   157 a.a.
NCBI ID   WP_192208621.1    Uniprot ID   A0A7L8W6X1
Organism   Streptococcus sp. KS 6     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 32345..42818
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FPL13_RS00225 (FPL13_00225) - 33659..34297 (+) 639 WP_049512994.1 adenylate kinase -
  FPL13_RS00230 (FPL13_00230) infA 34413..34631 (+) 219 WP_001029883.1 translation initiation factor IF-1 -
  FPL13_RS00235 (FPL13_00235) rpmJ 34656..34772 (+) 117 WP_001808836.1 50S ribosomal protein L36 -
  FPL13_RS00240 (FPL13_00240) rpsM 34788..35153 (+) 366 WP_002262317.1 30S ribosomal protein S13 -
  FPL13_RS00245 (FPL13_00245) rpsK 35173..35556 (+) 384 WP_001118385.1 30S ribosomal protein S11 -
  FPL13_RS00250 (FPL13_00250) - 35601..36539 (+) 939 WP_003029466.1 DNA-directed RNA polymerase subunit alpha -
  FPL13_RS00255 (FPL13_00255) rplQ 36551..36937 (+) 387 WP_003026513.1 50S ribosomal protein L17 -
  FPL13_RS00260 (FPL13_00260) comR/comR2 37345..37818 (+) 474 WP_192208621.1 sigma-70 family RNA polymerase sigma factor Regulator
  FPL13_RS00265 (FPL13_00270) rpsB 38054..38836 (+) 783 WP_049514303.1 30S ribosomal protein S2 -
  FPL13_RS00270 (FPL13_00275) tsf 38919..39962 (+) 1044 WP_049514302.1 translation elongation factor Ts -
  FPL13_RS00275 (FPL13_00280) - 40049..40399 (-) 351 WP_049514301.1 hypothetical protein -
  FPL13_RS00280 (FPL13_00285) - 40659..41120 (+) 462 WP_049514304.1 CtsR family transcriptional regulator -

Sequence

Protein


Download         Length: 157 a.a.        Molecular weight: 19253.09 Da        Isoelectric Point: 7.9719

>NTDB_id=374974 FPL13_RS00260 WP_192208621.1 37345..37818(+) (comR/comR2) [Streptococcus sp. KS 6]
MEFKELYGKVRGIVLKCRREYYVHLWELSDWDQEGMLVLYQLVSRYPQLVETESQLYVYYKTKFRNHILDILRKQESQKR
KLDRQAYEEVSEIGHKLSLKELYLDELVILRDQLKSYQAQLSPEKQEQYERLLADERFKGRQAMIRELRAYLKDYSD

Nucleotide


Download         Length: 474 bp        

>NTDB_id=374974 FPL13_RS00260 WP_192208621.1 37345..37818(+) (comR/comR2) [Streptococcus sp. KS 6]
ATGGAGTTCAAGGAGTTGTATGGGAAGGTAAGGGGGATTGTATTAAAGTGCCGTCGGGAATATTATGTCCACCTGTGGGA
ATTAAGCGATTGGGACCAAGAGGGCATGTTAGTACTCTATCAGTTGGTAAGTCGCTATCCGCAGCTGGTAGAGACAGAAA
GTCAGCTCTATGTTTACTATAAGACCAAGTTCCGCAATCATATCCTGGACATCCTCCGTAAACAGGAAAGCCAAAAACGC
AAACTCGATCGTCAAGCTTATGAAGAAGTGAGCGAGATAGGTCACAAGCTCAGCCTGAAAGAGTTGTATCTGGATGAATT
GGTGATTCTCCGAGACCAGCTAAAGAGCTATCAAGCTCAACTGAGTCCAGAGAAACAAGAGCAGTACGAGCGCTTACTAG
CTGATGAACGTTTCAAAGGCCGCCAAGCCATGATTCGAGAATTAAGAGCCTATTTAAAGGACTATAGCGATTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7L8W6X1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

60.256

99.363

0.599
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

60.256

99.363

0.599
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

55.195

98.089

0.541
  comX/comX2 Streptococcus pneumoniae D39

54.545

98.089

0.535
  comX/comX1 Streptococcus pneumoniae D39

54.545

98.089

0.535
  comX/comX1 Streptococcus pneumoniae R6

54.545

98.089

0.535
  comX/comX2 Streptococcus pneumoniae R6

54.545

98.089

0.535
  comX/comX2 Streptococcus pneumoniae Rx1

54.545

98.089

0.535
  comX/comX1 Streptococcus pneumoniae Rx1

54.545

98.089

0.535
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

54.545

98.089

0.535
  comX/comX2 Streptococcus pneumoniae TIGR4

53.896

98.089

0.529
  comX/comX1 Streptococcus pneumoniae TIGR4

53.896

98.089

0.529
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

53.896

98.089

0.529
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

53.247

98.089

0.522
  comX/sigX Streptococcus mutans UA159

48.718

99.363

0.484
  comX/sigX Streptococcus suis D9

47.097

98.726

0.465
  comX/sigX Streptococcus suis isolate S10

47.097

98.726

0.465
  comX/sigX Streptococcus suis P1/7

47.097

98.726

0.465
  comX Streptococcus salivarius SK126

44.156

98.089

0.433
  comX/sigX Streptococcus salivarius strain HSISS4

43.506

98.089

0.427
  comX Streptococcus thermophilus LMG 18311

43.506

98.089

0.427
  comX Streptococcus thermophilus LMD-9

43.506

98.089

0.427
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

42.308

99.363

0.42
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

42.308

99.363

0.42
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

42.308

99.363

0.42
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

42.308

99.363

0.42
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

42.308

99.363

0.42
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

42.308

99.363

0.42
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

38.462

99.363

0.382
  comX Streptococcus sobrinus strain NIDR 6715-7

39.216

97.452

0.382

Multiple sequence alignment