Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   G8B38_RS04355 Genome accession   NZ_CP049694
Coordinates   837297..837773 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain ABC122     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 832297..842773
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G8B38_RS04320 (G8B38_04355) - 832612..833214 (+) 603 WP_011054796.1 hypothetical protein -
  G8B38_RS04325 (G8B38_04360) - 833225..833998 (+) 774 WP_011528569.1 hypothetical protein -
  G8B38_RS04330 (G8B38_04365) - 834008..834229 (+) 222 WP_009880241.1 hypothetical protein -
  G8B38_RS04335 (G8B38_04370) - 834229..834888 (+) 660 WP_011528570.1 hypothetical protein -
  G8B38_RS04340 (G8B38_04375) - 834957..835391 (-) 435 WP_011017966.1 hypothetical protein -
  G8B38_RS04345 (G8B38_04380) sda3 835663..836463 (-) 801 WP_011285611.1 streptodornase Sda3 -
  G8B38_RS04350 (G8B38_04385) prx 836701..836889 (+) 189 WP_011528571.1 hypothetical protein Regulator
  G8B38_RS04355 (G8B38_04390) mutX 837297..837773 (+) 477 WP_002984880.1 8-oxo-dGTP diphosphatase Machinery gene
  G8B38_RS04360 (G8B38_04395) - 837831..839012 (+) 1182 WP_002984879.1 AI-2E family transporter -
  G8B38_RS04365 (G8B38_04400) - 839002..840249 (+) 1248 WP_002984878.1 tetratricopeptide repeat protein -
  G8B38_RS04370 (G8B38_04405) fbp54 840308..841960 (-) 1653 WP_021299312.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=374877 G8B38_RS04355 WP_002984880.1 837297..837773(+) (mutX) [Streptococcus pyogenes strain ABC122]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=374877 G8B38_RS04355 WP_002984880.1 837297..837773(+) (mutX) [Streptococcus pyogenes strain ABC122]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCCGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703

Multiple sequence alignment