Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   FOV14_RS05650 Genome accession   NZ_CP041784
Coordinates   1127152..1127808 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain IM1     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1122152..1132808
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOV14_RS05620 (FOV14_05675) oppF 1122681..1123598 (+) 918 WP_003155037.1 oligopeptide ABC transporter ATP-binding protein OppF -
  FOV14_RS05625 (FOV14_05680) - 1123705..1124892 (+) 1188 WP_057080092.1 putative glycoside hydrolase -
  FOV14_RS05630 (FOV14_05685) - 1125010..1125588 (+) 579 WP_003155035.1 GNAT family N-acetyltransferase -
  FOV14_RS05635 (FOV14_05690) spx 1125767..1126162 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  FOV14_RS05640 (FOV14_05695) - 1126220..1126876 (-) 657 WP_057080091.1 TerC family protein -
  FOV14_RS05645 - 1127059..1127169 (+) 111 Protein_1049 adaptor protein MecA -
  FOV14_RS05650 (FOV14_05700) mecA 1127152..1127808 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  FOV14_RS05655 (FOV14_05705) - 1127959..1129119 (+) 1161 WP_139886663.1 competence protein CoiA family protein -
  FOV14_RS05660 (FOV14_05710) pepF 1129347..1131176 (+) 1830 WP_024085125.1 oligoendopeptidase F Regulator
  FOV14_RS05665 - 1131214..1131381 (-) 168 WP_003155026.1 hypothetical protein -
  FOV14_RS05670 (FOV14_05715) spxH 1131667..1132569 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=374284 FOV14_RS05650 WP_003155032.1 1127152..1127808(+) (mecA) [Bacillus velezensis strain IM1]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=374284 FOV14_RS05650 WP_003155032.1 1127152..1127808(+) (mecA) [Bacillus velezensis strain IM1]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGATAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment