Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   FO444_RS03235 Genome accession   NZ_CP041759
Coordinates   609163..611613 (+) Length   816 a.a.
NCBI ID   WP_017864215.1    Uniprot ID   A0AAE4NT58
Organism   Lactococcus lactis subsp. lactis strain IMAU11823     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 604163..616613
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FO444_RS03210 (FO444_03230) - 604927..605439 (+) 513 WP_012897343.1 adenine phosphoribosyltransferase -
  FO444_RS03215 (FO444_03235) rpoE 605656..606219 (+) 564 WP_017864213.1 DNA-directed RNA polymerase subunit delta -
  FO444_RS03220 (FO444_03240) mltG 606356..608008 (+) 1653 WP_017864214.1 endolytic transglycosylase MltG -
  FO444_RS03225 (FO444_03245) greA 608068..608541 (+) 474 WP_025016857.1 transcription elongation factor GreA -
  FO444_RS03230 (FO444_03250) - 608718..609173 (+) 456 WP_010905471.1 CtsR family transcriptional regulator -
  FO444_RS03235 (FO444_03255) clpC 609163..611613 (+) 2451 WP_017864215.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  FO444_RS03240 (FO444_03260) raiA 611748..612305 (+) 558 WP_003129564.1 ribosome-associated translation inhibitor RaiA -
  FO444_RS03245 (FO444_03265) eno 612490..613791 (+) 1302 WP_010905473.1 surface-displayed alpha-enolase -
  FO444_RS03250 (FO444_03270) - 613906..614577 (-) 672 WP_058211162.1 ABC transporter ATP-binding protein -
  FO444_RS03255 (FO444_03275) - 614580..615653 (-) 1074 WP_017864217.1 ABC transporter permease -
  FO444_RS03260 (FO444_03280) - 615665..616234 (-) 570 WP_017864218.1 TetR/AcrR family transcriptional regulator -

Sequence

Protein


Download         Length: 816 a.a.        Molecular weight: 90416.81 Da        Isoelectric Point: 6.4806

>NTDB_id=373868 FO444_RS03235 WP_017864215.1 609163..611613(+) (clpC) [Lactococcus lactis subsp. lactis strain IMAU11823]
MKFENIKYTPTLDRILEKAEEYAQQYQYGTIESAHLLAAMATTSGSIAYSLLAGMNVDSSDLLIDLEDLSSHVKVKRSTL
RFSPRAEEVMTAASFLAIHNNSEAVGTEHLLYALLQVEDGFGLQLLKLQKINIVSLRKELEKRTGLKVPESKKAVTPMSK
RKMAKGVAENSTTPTLDSVSSDLTEEARLGKLDPMIGREAEIDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSSDPDVIIFIDELHTIIGAGGGMDSVNDAANILKPALAR
GDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDEAIAILQGLREKFEDYHQVKFTDQAIKSAVMLSVRYMTSRK
LPDKAIDLLDEAAAAVKISVKNQQTKRLDLEKELAEAQEELSEAVIKLDIKASRTKEKAVEKIADKIYKFSVKEDKRQEV
TDQAVVAVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGVADSRRPMGSFMFLGPTGVGK
TELAKALADSVFGSEDNMIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHPDVFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATALRDDKTVGFGAKNITADYSAMKSRILEELKRHYRPEFLNRIDENIVF
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAVKLIAEVGFDPEYGARPLRKALQKEVEDLLSEQLLSGEIKAGNH
VSIGASNKKIKIAQIV

Nucleotide


Download         Length: 2451 bp        

>NTDB_id=373868 FO444_RS03235 WP_017864215.1 609163..611613(+) (clpC) [Lactococcus lactis subsp. lactis strain IMAU11823]
ATGAAATTTGAAAATATAAAATATACACCAACGCTTGACCGAATTTTAGAAAAAGCGGAAGAGTATGCTCAACAATATCA
ATATGGCACCATTGAAAGTGCTCATTTACTAGCTGCAATGGCAACGACCTCAGGCTCAATTGCTTACAGCCTTCTTGCAG
GAATGAATGTTGATTCTTCTGACTTACTGATTGATTTAGAGGATTTATCAAGTCATGTTAAGGTCAAACGTTCAACTTTA
CGTTTTTCACCTCGTGCAGAGGAAGTGATGACTGCGGCAAGTTTTTTAGCAATTCATAATAACTCAGAAGCCGTTGGAAC
AGAACACTTGCTTTATGCCCTACTTCAAGTAGAAGATGGATTTGGTCTTCAACTTCTGAAATTACAAAAAATCAATATTG
TATCTTTGCGAAAAGAGCTTGAGAAAAGAACTGGACTCAAAGTTCCAGAAAGTAAAAAAGCTGTGACTCCAATGTCAAAA
CGTAAGATGGCAAAGGGAGTTGCAGAAAATTCAACGACGCCAACGTTAGACTCTGTATCCTCAGATTTAACCGAAGAAGC
TCGCTTGGGTAAACTTGACCCAATGATTGGACGAGAAGCTGAAATTGACCGTTTGATTCATATTCTCAGCCGCAGAACAA
AAAATAATCCTGTCTTAGTTGGAGAGCCCGGTGTTGGGAAATCAGCAATTATTGAAGGTTTGGCTCAAAGAATTGTCAAT
GGTCAAGTTCCAATTGGTTTGATGAATAGTCGAATTATGGCCTTGAATATGGCGACTGTTGTTGCTGGGACAAAATTTAG
AGGTGAATTTGAGGATCGTTTGACAGCTATTGTTGAAGAAGTTAGCAGTGATCCAGATGTCATTATTTTCATTGATGAAT
TACACACAATCATCGGTGCTGGTGGCGGTATGGATTCTGTCAATGATGCCGCAAATATTTTGAAACCAGCGCTTGCTCGT
GGTGATTTTCAAATGGTCGGAGCAACAACCTATCATGAATATCAAAAATATATTGAAAAAGATGAAGCTTTAGAACGCCG
TTTGGCGAGAATAAATGTTGATGAGCCAAGTCCAGATGAAGCGATTGCTATTTTGCAAGGCTTACGTGAAAAATTTGAAG
ACTATCATCAAGTGAAATTTACTGACCAAGCCATTAAAAGTGCTGTAATGCTCAGTGTTCGTTATATGACTAGCCGAAAA
TTGCCTGACAAAGCCATTGATTTACTTGATGAAGCTGCAGCAGCAGTGAAAATTTCTGTCAAAAATCAACAAACAAAACG
TCTTGATTTAGAAAAAGAATTAGCGGAAGCTCAAGAAGAATTATCAGAAGCTGTCATTAAACTTGATATCAAAGCGTCTC
GTACAAAAGAAAAAGCAGTTGAAAAAATTGCTGACAAGATTTATAAATTCTCAGTAAAAGAAGATAAACGTCAAGAAGTT
ACTGACCAAGCTGTTGTTGCTGTTGCCTCAACACTGACAGGTGTTCCAATCACACAAATGACTAAGTCTGAAAGTGATCG
TTTAATCAATCTTGAAAAAGAATTACACAAACGAGTTGTTGGACAAGAAGAAGCTATTTCTGCCGTTTCAAGAGCCATTC
GTCGGGCACGTTCCGGTGTTGCTGACAGCCGTCGTCCAATGGGTTCTTTCATGTTCCTTGGACCAACAGGGGTCGGTAAA
ACCGAACTTGCTAAAGCACTGGCTGACAGTGTGTTTGGTAGTGAAGATAATATGATTCGTGTTGACATGAGTGAATTCAT
GGAAAAACATTCGACTTCACGCTTGATTGGAGCTCCTCCAGGGTATGTAGGTTATGATGAGGGTGGTCAATTGACAGAAC
GCGTTCGTAATAAACCTTATTCTGTTGTTCTTTTAGATGAAGTCGAAAAAGCTCATCCTGACGTTTTCAACATCATGTTG
CAAATTCTAGATGATGGCTTTGTGACTGATACTAAAGGTCGTAAAGTTGATTTCAGAAATACAATTATTATCATGACTTC
AAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACAGTTGGTTTTGGCGCTAAAAATATCACAGCTGATTATTCAGCCA
TGAAATCAAGAATATTAGAAGAGCTTAAACGTCATTATCGTCCTGAGTTTCTTAATCGAATTGATGAAAATATTGTTTTC
CACTCATTGGAAAGTCAAGAGATTGAACAAATTGTTAAAATTATGAGTAAATCTTTGATTAAACGTCTGGCAGAACAAGA
TATTCATGTTAAACTCACACCGTCAGCGGTGAAATTAATTGCTGAGGTAGGTTTTGACCCAGAATATGGTGCACGTCCGC
TCCGCAAGGCTCTTCAAAAAGAAGTTGAAGACCTTTTAAGTGAACAATTGCTCTCTGGTGAAATCAAAGCAGGTAATCAT
GTTTCAATTGGGGCATCTAATAAAAAAATTAAAATCGCTCAAATTGTTTGA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(723-802)

AAA lid domain (AAA_lid_9)

(357-453)

ATPase family associated with various cellular activities (AAA) (AAA)

(218-334)

AAA domain (Cdc48 subfamily) (AAA_2)

(545-716)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(19-69)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(96-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

99.877

100

0.999
  clpC Streptococcus thermophilus LMD-9

50.542

100

0.515
  clpC Streptococcus thermophilus LMG 18311

50.421

100

0.513
  clpC Streptococcus pneumoniae Rx1

48.798

100

0.498
  clpC Streptococcus pneumoniae D39

48.798

100

0.498
  clpC Bacillus subtilis subsp. subtilis str. 168

50.499

98.284

0.496
  clpC Streptococcus pneumoniae TIGR4

48.678

100

0.496
  clpC Streptococcus mutans UA159

48.558

100

0.495
  clpE Streptococcus mutans UA159

47.846

79.657

0.381
  clpC Lactococcus lactis subsp. cremoris KW2

47.023

80.27

0.377
  clpE Streptococcus pneumoniae TIGR4

47.687

76.838

0.366
  clpE Streptococcus pneumoniae Rx1

47.687

76.838

0.366
  clpE Streptococcus pneumoniae D39

47.687

76.838

0.366
  clpE Streptococcus pneumoniae R6

47.687

76.838

0.366

Multiple sequence alignment