Detailed information NTG0037231

Bioinformatically predicted

Overview

• Name: hexB
• Type: Machinery gene
• Locus tag: ECTR2_RS14975
• Genome accession: NC_017343
• Coordinates: 1252118..1253284 (+)
• Length: 388 a.a.
• NCBI ID: WP_001806223.1
• Uniprot ID: B1VKA9
• Organism: Staphylococcus aureus subsp. aureus ECT-R
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1247118..1258284

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ECTR2_RS06075 (ECTR2_1149)	-	1248301..1248666 (+)	366	WP_000282386.1	RicAFT regulatory complex protein RicA family protein	-
ECTR2_RS06080 (ECTR2_1150)	thiW	1248693..1249184 (+)	492	WP_000842277.1	energy coupling factor transporter S component ThiW	-
ECTR2_RS06085 (ECTR2_1151)	hexA	1249487..1252105 (+)	2619	WP_000073352.1	DNA mismatch repair protein MutS	Machinery gene
ECTR2_RS14975 (ECTR2_1152)	hexB	1252118..1253284 (+)	1167	WP_001806223.1	DNA mismatch repair endonuclease MutL	Machinery gene
ECTR2_RS14980 (ECTR2_1153)	-	1253506..1254126 (+)	621	Protein_1174	DNA mismatch repair protein MutL	-
ECTR2_RS06095 (ECTR2_1154)	-	1254132..1254674 (+)	543	WP_001077635.1	glycerol-3-phosphate responsive antiterminator	-
ECTR2_RS06100 (ECTR2_1156)	-	1255149..1255967 (+)	819	WP_001103743.1	MIP/aquaporin family protein	-
ECTR2_RS06105 (ECTR2_1157)	glpK	1256096..1257592 (+)	1497	WP_000417372.1	glycerol kinase GlpK	-

Sequence

Protein

• Length: 388 a.a.
• Molecular weight: 43902.64 Da
• Isoelectric Point: 9.7302

>NTDB_id=37231 ECTR2_RS14975 WP_001806223.1 1252118..1253284(+) (hexB) [Staphylococcus aureus subsp. aureus ECT-R]
MGKIKELQTSLANKIAAGEVVERPSSVVKELLENAIDAGATEISIEVEESGVQSIRVVDNGSGIEAEDLGLVFHRHATSK
LDQDEDLFHIRTLGFRGEALASISSVAKVTLKTCTDNANGNEIYVENGEILNHKPAKAKKGTDILVESLFYNTPARLKYI
KSLYTELGKITDIVNRMAMSHPDIRIALISDGKTMLSTNGSGRTNEVMAEIYGMKVARDLVHISGDTSDYHIEGFVAKPE
HSRSNKHYISIFINGRYIKNFMLNKAILEGYHTLLTIGRFPICYINIEMDPILVDVNVHPTKLEVRLSKEEQLYQLIVSK
IQEAFKDRILIPKNNLDYVPKKIKYYIHSNNKKSNLNKDKTQRITKRRRFHLKKVTVSHLWQKIKTMR

Nucleotide

• Length: 1167 bp

>NTDB_id=37231 ECTR2_RS14975 WP_001806223.1 1252118..1253284(+) (hexB) [Staphylococcus aureus subsp. aureus ECT-R]
ATGGGGAAAATTAAAGAACTCCAAACCTCATTAGCAAATAAAATCGCAGCAGGTGAAGTAGTTGAAAGACCGAGTTCTGT
TGTGAAAGAACTGTTGGAAAATGCTATAGATGCAGGCGCTACAGAAATAAGCATTGAAGTAGAGGAATCTGGCGTCCAAT
CTATTCGCGTAGTCGATAATGGAAGCGGAATTGAAGCGGAAGACTTAGGATTAGTATTTCATAGACATGCGACTAGTAAA
TTAGATCAAGATGAAGATTTATTTCATATTAGGACATTAGGATTCCGTGGTGAAGCACTAGCCAGTATTTCATCAGTTGC
TAAAGTAACATTGAAGACTTGCACGGATAATGCTAATGGAAATGAAATATATGTAGAAAATGGTGAAATATTAAATCATA
AGCCTGCAAAAGCGAAAAAAGGAACAGATATACTTGTAGAATCATTATTTTATAATACACCAGCACGTTTAAAATATATT
AAAAGTTTATACACTGAACTAGGTAAAATAACAGATATTGTCAATAGAATGGCTATGAGCCATCCGGACATTCGAATAGC
ACTCATTTCAGATGGCAAAACAATGTTAAGTACAAATGGTTCAGGACGAACTAATGAAGTGATGGCAGAGATTTATGGGA
TGAAAGTTGCACGAGATTTAGTACATATATCTGGAGATACAAGTGATTATCACATTGAAGGTTTTGTTGCAAAGCCTGAA
CATTCTAGAAGTAATAAGCACTATATTTCTATTTTTATTAATGGACGATACATTAAAAACTTTATGCTAAATAAAGCGAT
TTTAGAAGGCTATCATACACTCTTAACAATAGGTAGGTTCCCGATTTGTTATATTAATATTGAAATGGATCCAATCTTAG
TAGACGTAAATGTTCATCCAACAAAACTAGAAGTGCGTTTATCAAAAGAAGAGCAACTATATCAATTGATAGTGAGCAAA
ATACAAGAAGCATTTAAAGACCGTATATTAATTCCTAAAAATAACTTGGATTATGTGCCAAAAAAAATAAAGTATTATAT
TCATTCGAACAACAAAAAATCGAATTTGAACAAAGACAAAACACAGAGAATAACCAAGAGAAGACGTTTTCATCTGAAGA
AAGTAACAGTAAGTCATTTATGGCAGAAAATCAAAACGATGAGATAG

Domains

Predicted by InterProScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3) (25-119)

• DNA mismatch repair protein, C-terminal domain (DNA_mis_repair) (209-325)

3D structure

• AlphaFold DB: B1VKA9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexB	Streptococcus pneumoniae R6	53.153	85.825	0.456