Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   ST64987_RS07660 Genome accession   NZ_CP049053
Coordinates   1456340..1458445 (-) Length   701 a.a.
NCBI ID   WP_167401589.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ST64987     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1451340..1463445
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST64987_RS07630 (ST64987_1450) pptB 1451806..1452840 (-) 1035 WP_375709249.1 ABC transporter permease Regulator
  ST64987_RS07635 (ST64987_1451) pptA 1452840..1453571 (-) 732 WP_002951673.1 ABC transporter ATP-binding protein Regulator
  ST64987_RS07640 (ST64987_1452) - 1453636..1454055 (+) 420 WP_011227486.1 HIT family protein -
  ST64987_RS07645 (ST64987_1453) - 1454052..1454351 (+) 300 WP_101415677.1 hypothetical protein -
  ST64987_RS07650 (ST64987_1454) - 1454403..1455131 (-) 729 WP_023909893.1 hypothetical protein -
  ST64987_RS07655 (ST64987_1455) - 1455149..1455784 (-) 636 WP_023909894.1 DUF4230 domain-containing protein -
  ST64987_RS10500 - 1455803..1455928 (-) 126 WP_259699999.1 hypothetical protein -
  ST64987_RS07660 (ST64987_1456) clpC 1456340..1458445 (-) 2106 WP_167401589.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  ST64987_RS07665 (ST64987_1457) - 1459159..1460250 (-) 1092 WP_011681536.1 nucleotidyltransferase -
  ST64987_RS07670 (ST64987_1458) - 1460257..1460997 (-) 741 WP_277426406.1 class I SAM-dependent methyltransferase -
  ST64987_RS07675 (ST64987_1459) rsfS 1461322..1461675 (-) 354 WP_011227491.1 ribosome silencing factor -
  ST64987_RS07680 (ST64987_1460) yqeK 1461699..1462289 (-) 591 WP_002951696.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  ST64987_RS07685 (ST64987_1461) - 1462286..1462918 (-) 633 WP_002951698.1 nicotinate-nucleotide adenylyltransferase -
  ST64987_RS07690 (ST64987_1462) yhbY 1463022..1463339 (-) 318 WP_002951701.1 ribosome assembly RNA-binding protein YhbY -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77360.22 Da        Isoelectric Point: 4.7951

>NTDB_id=371931 ST64987_RS07660 WP_167401589.1 1456340..1458445(-) (clpC) [Streptococcus thermophilus strain ST64987]
MNNNFNNMDDLFNQLMGNMGGFRSESRRYMINGREVSPEEFAIYRQTGKLPGNQGEAVNPTQQQGNGPKQDGILAKIGRN
LTQEAREGKLDPVIGRNKEIQETSEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKDKEIISIDISALEA
GTQYRGSFEENIQNLINEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGEITVIGATTQDEYRNTILK
NAALARRFNEVKVNAPSPEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLLDVTAAHLAAQH
PVTDVNAVEREIEEEKAKQEAAVAKEDYEAALNSKIRIEKLEKEIANHAKDRKVTATVNDVAESVERMTGIPVSQMGATD
IERLKDMSNRLQAKVIGQDKAVEAVARSIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDLFGTKDAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVI
IATSNAGFGYESNSTEDADKPELMDRLKPYFRPEFLNRFDAVIEFSHLDKEDLSKIVDLMLNEVNKTLSKKGIDLAVSEA
AKAYMTEEGYDEVMGARPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=371931 ST64987_RS07660 WP_167401589.1 1456340..1458445(-) (clpC) [Streptococcus thermophilus strain ST64987]
ATGAACAACAACTTTAATAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTTCCGTTCAGAAAGCCG
TCGCTACATGATTAACGGTCGTGAAGTGTCACCTGAAGAATTTGCAATTTACCGTCAAACAGGTAAATTGCCTGGTAATC
AAGGTGAAGCAGTGAACCCAACGCAACAACAGGGTAACGGACCTAAACAAGATGGTATTCTTGCTAAAATTGGTCGTAAC
TTGACTCAAGAAGCTCGTGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAACTAGCGAAATCTT
GGCTCGTCGTACTAAGAATAACCCAGTCCTTGTCGGTGATGCTGGGGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCAC
AAGCCATCGTTAATGGTGATGTCCCAGCTGCTATCAAGGACAAAGAAATCATCTCAATTGATATTTCTGCACTTGAAGCT
GGTACTCAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGATAAATGAAGTCAAAGAAGCTGGAAACATTATCCT
CTTCTTCGATGAAATTCATCAAATTCTTGGTGCCGGAAGCACTGGCGATGGTCAAGGTTCTAAAGGTCTGGCTGATATCT
TGAAACCTGCTCTTTCACGTGGTGAAATAACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAG
AATGCTGCCCTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTCCTGAAGATACCTTCAAGATTCTTCAAGG
TATTCGTGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTCTTGAAAGCAGCGGTTGATTTTTCAGTAC
AATACATTCCACAACGTAGCTTGCCAGATAAGGCTATTGACCTTTTGGACGTAACAGCAGCTCACTTGGCAGCACAACAT
CCAGTAACTGATGTCAATGCTGTTGAACGTGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGTTGCTAAAGAAGA
TTACGAAGCAGCTCTAAATTCTAAGATTCGTATTGAAAAACTTGAAAAGGAAATTGCTAACCATGCAAAAGATCGCAAGG
TGACTGCGACTGTAAACGATGTGGCTGAATCCGTAGAACGTATGACTGGTATTCCAGTATCTCAAATGGGTGCAACGGAT
ATCGAACGTTTGAAAGATATGAGTAACCGTTTGCAAGCTAAGGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGGCACG
TTCCATCCGTCGTAATCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTG
TTGGTAAAACTGAGTTGGCTAAACAATTGGCCCTTGATTTGTTCGGTACCAAAGATGCTATCATCCGTTTGGACATGTCA
GAATACAGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGATAATAGTAATAC
CTTGACAGAACGTGTTCGTCGTAACCCTTATTCAATCATCCTTCTTGATGAAATTGAAAAGGCAGACCCTCAAGTTATCA
CCCTTCTCCTCCAAGTTTTGGATGATGGCCGTTTGACTGATGGTCAAGGTAATACTGTAAACTTCAAGAACACAGTCATT
ATCGCAACTTCAAACGCTGGCTTTGGTTACGAATCTAACTCGACAGAAGATGCTGATAAACCAGAACTCATGGATCGTTT
GAAACCTTACTTCCGTCCTGAATTCCTTAACCGTTTCGACGCAGTTATTGAGTTCTCACACTTAGATAAGGAGGACCTTT
CTAAGATTGTCGATCTTATGTTGAATGAAGTTAACAAGACTCTTTCTAAGAAAGGCATTGACTTGGCAGTTAGCGAAGCT
GCTAAAGCCTATATGACAGAAGAAGGCTATGATGAAGTTATGGGTGCTCGTCCACTCCGTCGTGTGGTTGAACAACAAAT
CCGTGACAAAGTCACAGACTTCCACTTGGATAACCTTGATGCAAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTAG
TTATCAAAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

AAA lid domain (AAA_lid_9)

(257-351)

AAA domain (Cdc48 subfamily) (AAA_2)

(441-601)

ATPase family associated with various cellular activities (AAA) (AAA)

(116-248)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(608-678)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

49.002

92.867

0.455
  clpE Streptococcus mutans UA159

49.533

91.583

0.454
  clpE Streptococcus pneumoniae D39

48.131

91.583

0.441
  clpE Streptococcus pneumoniae Rx1

48.131

91.583

0.441
  clpE Streptococcus pneumoniae R6

48.131

91.583

0.441
  clpE Streptococcus pneumoniae TIGR4

48.05

91.441

0.439
  clpC Bacillus subtilis subsp. subtilis str. 168

45.263

94.864

0.429
  clpC Streptococcus thermophilus LMD-9

44.246

88.017

0.389
  clpC Streptococcus thermophilus LMG 18311

44.084

88.017

0.388
  clpC Streptococcus pneumoniae TIGR4

43.499

88.873

0.387
  clpC Streptococcus pneumoniae Rx1

43.499

88.873

0.387
  clpC Streptococcus pneumoniae D39

43.499

88.873

0.387
  clpC Streptococcus mutans UA159

43.156

88.588

0.382
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

43.112

88.017

0.379