Detailed information NTG0371920

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: ST64987_RS06705
• Genome accession: NZ_CP049053
• Coordinates: 1270745..1271830 (-)
• Length: 361 a.a.
• NCBI ID: WP_011226304.1
• Uniprot ID: Q5M3H6
• Organism: Streptococcus thermophilus strain ST64987
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1265745..1276830

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST64987_RS06680 (ST64987_1266)	-	1265856..1266554 (+)	699	WP_011226301.1	ABC transporter ATP-binding protein	-
ST64987_RS06685 (ST64987_1267)	-	1266566..1267351 (+)	786	WP_011681414.1	hypothetical protein	-
ST64987_RS06690	-	1267429..1268315 (-)	887	Protein_1230	transposase	-
ST64987_RS06695 (ST64987_1269)	-	1268511..1269767 (+)	1257	WP_011680631.1	ISL3 family transposase	-
ST64987_RS06700 (ST64987_1270)	-	1269823..1270752 (-)	930	WP_082245810.1	ATP-binding cassette domain-containing protein	-
ST64987_RS06705 (ST64987_1271)	amiE	1270745..1271830 (-)	1086	WP_011226304.1	ABC transporter ATP-binding protein	Regulator
ST64987_RS06710 (ST64987_1272)	amiD	1271840..1272766 (-)	927	WP_002946409.1	oligopeptide ABC transporter permease OppC	Regulator
ST64987_RS06715 (ST64987_1273)	amiC	1272766..1274259 (-)	1494	WP_167401557.1	ABC transporter permease	Regulator
ST64987_RS06720 (ST64987_1274)	amiA	1274321..1276288 (-)	1968	WP_014621802.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 39864.62 Da
• Isoelectric Point: 4.7435

>NTDB_id=371920 ST64987_RS06705 WP_011226304.1 1270745..1271830(-) (amiE) [Streptococcus thermophilus strain ST64987]
MTENKNVILSARDIVVEFDVRDRVLTAIRGVSLDLVEGEVLALVGESGSGKSVLTKTFTGMLEENGRVASGSIDYRGKDL
TKFKSHQDWAAIRGAKIATIFQDPMTSLNPIKTIGSQIIEVIVKHQGKTAKEAKKMAIDYMDKVGIPDAEKRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLKEEYGFSVIFITHDLGVVASIADKVAVMYAGEIIE
YATVEEIFYEPCHPYTWSLLSSLPQLADDNGKLFSIPGTPPSLYTPVVGDAFALRSDYALQIDFEEKAPQFQVSDTHWAK
TWLLHEDAPKVDKPAVIQNLHEKILANMGFAHLGDEEEGNA

Nucleotide

• Length: 1086 bp

>NTDB_id=371920 ST64987_RS06705 WP_011226304.1 1270745..1271830(-) (amiE) [Streptococcus thermophilus strain ST64987]
ATGACAGAAAATAAAAATGTAATATTATCGGCTCGCGATATCGTCGTGGAATTTGACGTTCGTGACCGTGTTTTGACAGC
TATTCGAGGGGTTTCTCTTGATTTAGTTGAAGGTGAAGTTTTAGCCTTGGTTGGTGAGTCTGGTTCAGGAAAATCAGTCT
TGACTAAAACTTTTACAGGGATGCTGGAAGAAAATGGTCGTGTAGCTAGCGGATCTATCGACTACCGTGGCAAAGACTTG
ACTAAATTTAAGAGTCACCAAGATTGGGCAGCTATCCGTGGAGCTAAGATTGCAACTATTTTCCAAGATCCAATGACCAG
TCTTAACCCAATTAAGACTATCGGAAGTCAAATTATTGAAGTTATTGTTAAGCACCAAGGGAAAACAGCCAAGGAAGCTA
AAAAAATGGCAATTGATTACATGGACAAGGTTGGTATTCCAGATGCTGAAAAACGTTTCAATGAATATCCTTTCCAATAC
TCTGGTGGGATGCGTCAACGTATCGTTATTGCCATTGCCTTGGCTTGTCGTCCTGATGTCCTTATCTGTGACGAACCAAC
AACTGCCCTTGATGTGACCATTCAAGCTCAAATCATTGACCTCTTGAAATCACTCAAAGAGGAGTATGGTTTCTCGGTCA
TTTTCATTACCCATGACCTTGGCGTCGTAGCAAGTATCGCGGACAAGGTTGCTGTCATGTATGCTGGCGAAATCATTGAA
TACGCAACTGTTGAGGAAATTTTCTATGAGCCTTGTCATCCATACACGTGGAGCTTGCTTTCAAGTCTGCCACAATTGGC
TGATGATAATGGAAAACTCTTCTCAATTCCAGGGACGCCACCATCACTTTATACACCAGTTGTTGGGGATGCCTTTGCCT
TGCGTTCAGATTATGCTTTGCAGATTGATTTTGAGGAAAAAGCACCACAATTCCAAGTTTCAGATACTCACTGGGCTAAG
ACCTGGCTCTTACATGAGGATGCGCCAAAAGTTGATAAACCTGCGGTTATCCAAAATCTACATGAAAAAATCCTAGCCAA
TATGGGATTTGCACATTTAGGAGATGAGGAGGAAGGCAATGCCTGA

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-300)

3D structure

• AlphaFold DB: Q5M3H6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus thermophilus LMG 18311	100	100	1
amiE	Streptococcus thermophilus LMD-9	100	100	1
amiE	Streptococcus salivarius strain HSISS4	96.953	100	0.97
oppD	Streptococcus mutans UA159	54.441	96.676	0.526