Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilQ   Type   Machinery gene
Locus tag   LPA_RS05050 Genome accession   NC_014125
Coordinates   1100046..1102142 (+) Length   698 a.a.
NCBI ID   WP_011946023.1    Uniprot ID   A0A378K6J3
Organism   Legionella pneumophila 2300/99 Alcoy     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1095046..1107142
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPA_RS05025 (lpa_01397) - 1095808..1096815 (-) 1008 WP_013101264.1 hypothetical protein -
  LPA_RS05030 (lpa_01398) pilM 1097232..1098296 (+) 1065 WP_013101265.1 type IV pilus assembly protein PilM Machinery gene
  LPA_RS05035 (lpa_01400) pilN 1098300..1098848 (+) 549 WP_013101266.1 PilN domain-containing protein Machinery gene
  LPA_RS05040 (lpa_01401) pilO 1098862..1099461 (+) 600 WP_013101267.1 type 4a pilus biogenesis protein PilO Machinery gene
  LPA_RS05045 (lpa_01402) pilP 1099458..1100042 (+) 585 WP_013101268.1 pilus assembly protein PilP Machinery gene
  LPA_RS05050 (lpa_01404) pilQ 1100046..1102142 (+) 2097 WP_011946023.1 type IV pilus secretin PilQ Machinery gene
  LPA_RS05055 (lpa_01405) aroK 1102589..1103116 (+) 528 WP_010946667.1 shikimate kinase AroK -
  LPA_RS05060 (lpa_01407) aroB 1103103..1104212 (+) 1110 WP_013101269.1 3-dehydroquinate synthase -
  LPA_RS05065 (lpa_01408) - 1104209..1105660 (+) 1452 WP_013101270.1 SPOR domain-containing protein -
  LPA_RS05070 (lpa_01409) - 1105769..1106200 (+) 432 WP_010946670.1 universal stress protein -

Sequence

Protein


Download         Length: 698 a.a.        Molecular weight: 77497.79 Da        Isoelectric Point: 9.5395

>NTDB_id=37130 LPA_RS05050 WP_011946023.1 1100046..1102142(+) (pilQ) [Legionella pneumophila 2300/99 Alcoy]
MRKIIAVLILISASLSMAYPKDNSLISVKVLPLPENRVRIDFQFSKPLKQLPASFITQKPPRLVLDFISTDMQIPSDQKT
KTIQLGSLHSYNIVAVGDRVRAILELDRSVSYSGSTAGSVYSLVLNGKSNDLFENSKEVFITNQVVNAKHEIKRIDFRGI
EKQGGRVLIDVSDTGIPIDVTQVGKEIVVNFLNTRIPLNLMKRYDVSDFHSPVQIITMQQEGKKVRMTILSKGDYGHFVY
QVNKQFMVDVFPLTAEEIRQAKLKKQVFTGKRISLNFQNISIRAVLQLLADFTGINMVVSDKVQGDITLRLNDIPWDQAL
DIILTTQGLDKRRKGNVMLIDTKASMDKMEEEQLKSQQTIEKLEPIRSDLIQINYAKAADIAVLIKDKQNSLLSDRGKIS
VDARTNTIWIQDTGTKIEEVRELIKQLDIPVKQVLIEARIVEVTKDFSQDIGIRWGVSRPTHLSGTLEGANELARGTAPA
NVVPLERRLNLDLAAAPLTGATPASVGIALAKLNDNILLDLELSALESEGRAELISSPRLITTNQQAAVIESGEEIPYQE
ATSSGATAVAFKKAVLSLKVTPQITPDGKILMDLQINQDTPSPQTFLGVPAIITKEIQTNVLVNNGQTIVLGGIYKQDKN
KVINRIPFFGELPVVGILFSNRQITLKNEELLIFITPRIITNALSITTIEGREKDVYK

Nucleotide


Download         Length: 2097 bp        

>NTDB_id=37130 LPA_RS05050 WP_011946023.1 1100046..1102142(+) (pilQ) [Legionella pneumophila 2300/99 Alcoy]
GTGAGAAAAATTATCGCGGTTTTGATATTAATTAGTGCCAGTTTGAGTATGGCATATCCTAAAGATAATTCACTCATTTC
AGTAAAAGTATTACCATTGCCTGAAAACAGAGTGCGCATTGATTTTCAATTTTCCAAACCCTTAAAGCAGTTGCCCGCAA
GCTTTATTACTCAAAAGCCCCCACGTTTGGTGTTAGATTTTATCAGCACTGATATGCAAATTCCTTCAGATCAGAAAACT
AAAACCATTCAATTAGGCTCATTACATAGCTATAACATTGTTGCTGTTGGGGATAGAGTAAGAGCCATATTGGAGCTGGA
TCGTTCAGTGTCCTATTCTGGCAGTACGGCGGGTTCCGTTTATAGCCTTGTCCTGAATGGTAAAAGCAATGATTTATTTG
AAAATAGCAAGGAAGTATTCATAACGAACCAGGTTGTGAACGCCAAGCATGAAATTAAAAGAATTGATTTTCGTGGTATA
GAAAAGCAGGGCGGTAGAGTTTTAATTGATGTTTCTGATACTGGTATTCCAATTGATGTAACTCAAGTTGGGAAAGAAAT
AGTCGTTAATTTCCTGAATACCAGGATCCCTTTGAATTTAATGAAACGGTATGATGTTTCTGATTTTCACAGCCCTGTGC
AGATTATTACTATGCAACAGGAAGGAAAAAAGGTTCGTATGACCATTCTCAGCAAAGGGGATTATGGGCATTTTGTTTAT
CAGGTCAATAAACAATTTATGGTCGATGTCTTTCCTTTAACTGCGGAAGAAATTCGTCAGGCGAAATTGAAGAAACAGGT
ATTTACCGGTAAACGGATTTCTTTGAATTTCCAGAATATTAGTATTCGAGCTGTGCTTCAACTGCTGGCAGATTTTACCG
GAATCAATATGGTTGTCAGCGACAAAGTGCAAGGAGATATTACGCTAAGATTAAATGATATTCCCTGGGATCAGGCGCTG
GATATCATTTTAACCACACAAGGGTTAGATAAGCGCAGAAAGGGCAACGTCATGTTGATAGATACCAAGGCCTCCATGGA
TAAAATGGAGGAAGAACAACTCAAAAGTCAACAGACAATTGAAAAACTTGAGCCTATTCGTTCTGATTTAATACAGATTA
ATTATGCAAAGGCAGCAGATATTGCTGTTTTGATCAAGGATAAGCAAAATTCCCTATTATCAGACAGAGGAAAAATAAGT
GTTGATGCCAGAACGAATACAATCTGGATTCAGGATACTGGCACCAAAATTGAGGAAGTAAGGGAACTGATAAAGCAATT
GGATATCCCTGTTAAGCAAGTGCTTATTGAGGCAAGAATTGTTGAAGTAACTAAAGATTTTAGTCAAGATATTGGGATAC
GCTGGGGGGTATCAAGACCAACTCACTTAAGCGGTACATTGGAAGGTGCTAACGAGTTAGCGAGAGGAACAGCACCAGCT
AATGTTGTCCCCTTGGAAAGACGATTAAATCTTGATTTGGCAGCTGCTCCTTTAACTGGAGCTACACCGGCCTCGGTAGG
TATTGCTCTAGCCAAGCTTAATGATAACATTCTGCTTGATCTGGAATTGTCTGCTTTGGAAAGTGAAGGGCGTGCTGAAT
TAATATCCAGTCCCCGCCTGATTACTACGAATCAACAGGCAGCAGTCATCGAGTCTGGTGAGGAGATTCCCTATCAGGAG
GCAACATCGAGTGGAGCGACGGCTGTTGCATTTAAAAAAGCAGTGTTGAGTTTGAAAGTTACCCCGCAAATTACGCCTGA
CGGTAAAATTTTGATGGATTTACAGATAAATCAGGATACTCCTTCTCCACAAACATTCCTTGGTGTTCCAGCAATAATAA
CAAAGGAGATTCAGACGAATGTTCTGGTTAATAATGGACAAACCATAGTACTTGGGGGTATTTATAAGCAAGATAAGAAC
AAGGTAATCAATAGAATTCCTTTCTTTGGTGAGTTGCCTGTTGTCGGTATTTTATTTAGTAATAGACAAATCACATTGAA
AAATGAAGAATTACTTATTTTTATTACACCAAGAATAATAACGAATGCCCTATCGATAACAACGATAGAAGGACGTGAAA
AAGATGTTTATAAATAA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(525-680)

AMIN domain (AMIN)

(39-113)

Bacterial type II/III secretion system short domain (Secretin_N)

(370-433)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A378K6J3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilQ Legionella pneumophila strain Lp02

99.427

100

0.994
  pilQ Legionella pneumophila strain ERS1305867

99.284

100

0.993
  comQ Acinetobacter baylyi ADP1

38.428

98.424

0.378
  pilQ Pseudomonas aeruginosa PAK

38.102

98.138

0.374

Multiple sequence alignment