Detailed information NTG0037118

Bioinformatically predicted

Overview

• Name: eppA
• Type: Machinery gene
• Locus tag: METIN_RS06770
• Genome accession: NC_014122
• Coordinates: 1208316..1209311 (-)
• Length: 331 a.a.
• NCBI ID: WP_013100741.1
• Uniprot ID: D5VTU3
• Organism: Methanocaldococcus infernus ME
• Function: DNA uptake (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1203316..1214311

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
METIN_RS06745 (Metin_1341)	-	1203384..1203884 (+)	501	WP_013100736.1	4Fe-4S dicluster domain-containing protein	-
METIN_RS06750 (Metin_1342)	-	1203881..1204291 (+)	411	WP_013100737.1	4Fe-4S dicluster domain-containing protein	-
METIN_RS06755 (Metin_1343)	hemL	1204280..1205545 (-)	1266	WP_013100738.1	glutamate-1-semialdehyde 2,1-aminomutase	-
METIN_RS06760 (Metin_1344)	cdhD	1205676..1206869 (+)	1194	WP_083771765.1	CO dehydrogenase/acetyl-CoA synthase subunit delta	-
METIN_RS06765 (Metin_1345)	acsC	1206880..1208319 (+)	1440	WP_013100740.1	acetyl-CoA decarbonylase/synthase complex subunit gamma	-
METIN_RS06770 (Metin_1346)	eppA	1208316..1209311 (-)	996	WP_013100741.1	A24 family peptidase C-terminal domain-containing protein	Machinery gene
METIN_RS06775 (Metin_1347)	-	1209308..1209649 (-)	342	WP_013100742.1	cysteine-rich small domain-containing protein	-
METIN_RS06780 (Metin_1348)	-	1209676..1210821 (-)	1146	WP_013100743.1	alanine--glyoxylate aminotransferase family protein	-
METIN_RS06785 (Metin_1349)	fsa	1210823..1211482 (-)	660	WP_013100744.1	fructose-6-phosphate aldolase	-
METIN_RS06790 (Metin_1350)	-	1211675..1212115 (+)	441	WP_013100745.1	V4R domain-containing protein	-
METIN_RS06795 (Metin_1351)	-	1212127..1213968 (+)	1842	WP_013100746.1	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C-terminal domain	-

Sequence

Protein

• Length: 331 a.a.
• Molecular weight: 38629.78 Da
• Isoelectric Point: 8.9580

>NTDB_id=37118 METIN_RS06770 WP_013100741.1 1208316..1209311(-) (eppA) [Methanocaldococcus infernus ME]
MSLLDIAYIINFFILILASITDIKEKIIPHKYVIAMFLINLPIGYYFFGFDAIIGMISTFILCLILSIGMGGGDVKLFTA
LAPIFSYDLFYFLPKPILYMIAISMLLVAIYPLFKIFRRYYKEILYSSFYLATVMGILYYIIYKLNIPYGTILIYLYIIV
SIFYLKKNKKYKEISKKLAYFFPLYLLLIYLLDKEYFIKNNLLLSSIIYIFEIILIALVVYALAGAEISTKKKIDELKEG
DILRDVIIFKDNDDVEVKNLSLLGRIKFMLENKEKNYLLCDGEGLSEEDIEKLKKYKDKIKELTVIETYPYVPFVTLSYV
IIILLTKLNIL

Nucleotide

• Length: 996 bp

>NTDB_id=37118 METIN_RS06770 WP_013100741.1 1208316..1209311(-) (eppA) [Methanocaldococcus infernus ME]
ATGAGCCTCTTAGACATAGCTTATATAATAAATTTTTTTATTTTAATTTTGGCATCAATAACAGATATAAAAGAAAAAAT
TATTCCTCACAAGTATGTTATAGCCATGTTTTTAATTAACCTTCCTATTGGTTACTATTTTTTTGGCTTTGATGCTATTA
TTGGGATGATAAGCACTTTTATCTTATGTTTAATTTTAAGCATTGGGATGGGAGGAGGAGATGTTAAGCTCTTCACAGCC
TTAGCCCCAATTTTTTCCTATGACTTATTTTACTTCCTACCCAAGCCAATCTTATATATGATAGCCATAAGTATGCTCTT
AGTAGCCATCTATCCATTATTTAAAATTTTTAGGAGATATTATAAGGAAATCTTATACTCTTCCTTTTATTTAGCCACTG
TTATGGGAATCCTTTACTATATAATTTATAAGCTAAATATTCCCTATGGAACAATTCTAATTTATTTATATATAATAGTG
TCAATCTTTTACCTAAAGAAGAATAAAAAATATAAGGAGATATCTAAGAAGTTAGCCTACTTTTTCCCCCTCTATCTTCT
CCTTATCTACCTCTTGGACAAAGAATACTTTATAAAGAATAACTTACTCCTAAGCTCAATAATTTATATATTTGAGATAA
TTCTTATAGCTTTGGTTGTCTATGCCCTTGCTGGAGCTGAGATCTCTACAAAGAAGAAAATTGATGAGCTTAAAGAAGGA
GATATTTTAAGGGATGTAATAATCTTTAAAGATAATGATGATGTAGAGGTTAAAAATCTCTCACTCCTTGGTAGAATTAA
ATTTATGCTTGAAAATAAGGAAAAGAACTATCTTCTATGTGATGGAGAGGGGTTAAGTGAAGAGGATATAGAGAAGTTAA
AAAAGTATAAGGATAAGATTAAAGAGCTTACAGTGATTGAAACCTATCCCTATGTTCCCTTTGTTACACTCTCCTATGTA
ATCATTATCTTACTAACCAAGCTAAATATTCTCTAA

Domains

Predicted by InterproScan.

• Archaeal Peptidase A24 C-terminal Domain (Arc_PepC) (206-301)

• Type IV leader peptidase family (Peptidase_A24) (10-113)

3D structure

• AlphaFold DB: D5VTU3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
eppA	Methanococcus maripaludis strain DSM 2067	49.387	98.489	0.486