Detailed information NTG0037115

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: HMPREF0772_RS10490
• Genome accession: NC_017342
• Coordinates: 2083850..2084623 (-)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus subsp. aureus TCH60
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 2078850..2089623

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF0772_RS10455	-	2079104..2079873 (-)	770	Protein_1982	isoprenyl transferase	-
HMPREF0772_RS10460 (HMPREF0772_11971)	frr	2080246..2080800 (-)	555	WP_001280006.1	ribosome recycling factor	-
HMPREF0772_RS10465 (HMPREF0772_11972)	pyrH	2080819..2081541 (-)	723	WP_000057330.1	UMP kinase	-
HMPREF0772_RS10470 (HMPREF0772_11973)	tsf	2081678..2082559 (-)	882	WP_000201387.1	translation elongation factor Ts	-
HMPREF0772_RS10475	-	2082594..2082707 (-)	114	WP_001791405.1	hypothetical protein	-
HMPREF0772_RS10480 (HMPREF0772_11974)	rpsB	2082741..2083508 (-)	768	WP_000268484.1	30S ribosomal protein S2	-
HMPREF0772_RS10485	-	2083707..2083799 (-)	93	WP_031788481.1	hypothetical protein	-
HMPREF0772_RS10490 (HMPREF0772_11975)	codY	2083850..2084623 (-)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
HMPREF0772_RS10495 (HMPREF0772_11976)	hslU	2084648..2086051 (-)	1404	WP_000379058.1	ATP-dependent protease ATPase subunit HslU	-
HMPREF0772_RS10500 (HMPREF0772_11977)	hslV	2086117..2086662 (-)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
HMPREF0772_RS10505 (HMPREF0772_11978)	xerC	2086659..2087555 (-)	897	WP_001015609.1	tyrosine recombinase XerC	-
HMPREF0772_RS10510 (HMPREF0772_11979)	trmFO	2087973..2089280 (-)	1308	WP_000195249.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=37115 HMPREF0772_RS10490 WP_000055337.1 2083850..2084623(-) (codY) [Staphylococcus aureus subsp. aureus TCH60]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=37115 HMPREF0772_RS10490 WP_000055337.1 2083850..2084623(-) (codY) [Staphylococcus aureus subsp. aureus TCH60]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGCGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACACGATG
ACTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCAAT
TGAACATATCTTTGAAGAACTTGGCGGTACAGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAGTAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428