Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   GAU34_RS12350 Genome accession   NZ_CP048643
Coordinates   2479227..2479901 (-) Length   224 a.a.
NCBI ID   WP_001166500.1    Uniprot ID   Q99VW2
Organism   Staphylococcus aureus strain SR153     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2474227..2484901
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GAU34_RS12335 (GAU34_12335) vraG 2475410..2477299 (-) 1890 WP_000143615.1 ABC transporter permease VraG -
  GAU34_RS12340 (GAU34_12340) vraF 2477289..2478050 (-) 762 WP_000985996.1 ABC transporter ATP-binding protein VraF -
  GAU34_RS12345 (GAU34_12345) graS 2478194..2479234 (-) 1041 WP_001061264.1 histidine kinase GraS/ApsS -
  GAU34_RS12350 (GAU34_12350) braR 2479227..2479901 (-) 675 WP_001166500.1 response regulator transcription factor GraR/ApsR Regulator
  GAU34_RS12355 (GAU34_12355) graX 2479917..2480840 (-) 924 WP_000802955.1 auxiliary protein GraX/ApsX -
  GAU34_RS12360 (GAU34_12360) - 2480953..2481459 (+) 507 WP_000940129.1 GNAT family N-acetyltransferase -
  GAU34_RS12365 (GAU34_12365) - 2481668..2482096 (-) 429 WP_000198504.1 hypothetical protein -
  GAU34_RS12370 (GAU34_12370) - 2482425..2483468 (-) 1044 WP_001030772.1 alpha/beta hydrolase -
  GAU34_RS12375 (GAU34_12375) - 2483619..2484686 (-) 1068 WP_000980137.1 membrane protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 26065.87 Da        Isoelectric Point: 4.3563

>NTDB_id=370202 GAU34_RS12350 WP_001166500.1 2479227..2479901(-) (braR) [Staphylococcus aureus strain SR153]
MQILLVEDDNTLFQELKKELEQWDFNVAGIEDFGKVMDTFESFNPEIVILDVQLPKYDGFYWCRKMREVSNVPILFLSSR
DNPMDQVMSMELGADDYMQKPFYTNVLIAKLQAIYRRVYEFTAEEKRTLTWQDAVVDLSKDSIQKGDDTIFLSKTEMIIL
EILITKKNQIVSRDTIITALWDDEAFVSDNTLTVNVNRLRKKLSEISMDSAIETKVGKGYMAHE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=370202 GAU34_RS12350 WP_001166500.1 2479227..2479901(-) (braR) [Staphylococcus aureus strain SR153]
ATGCAAATACTACTAGTAGAAGATGACAATACTTTGTTTCAAGAATTGAAAAAAGAATTAGAACAATGGGATTTTAATGT
TGCTGGTATTGAAGATTTCGGCAAAGTAATGGATACATTTGAAAGTTTTAATCCTGAAATTGTTATATTGGATGTTCAAT
TACCTAAATATGATGGGTTTTATTGGTGCAGAAAAATGAGAGAAGTTTCCAACGTACCAATATTATTTTTATCATCTCGT
GATAATCCAATGGATCAAGTGATGAGTATGGAACTTGGCGCAGATGATTATATGCAAAAACCTTTCTATACCAATGTATT
AATTGCTAAATTACAAGCGATTTATCGTCGTGTCTATGAGTTTACAGCTGAAGAAAAACGTACATTGACTTGGCAAGATG
CTGTCGTTGATCTATCAAAAGATAGTATACAAAAAGGTGACGATACGATTTTTCTATCCAAAACAGAAATGATTATATTA
GAAATTCTTATTACCAAAAAAAATCAAATCGTTTCGAGAGATACAATTATCACTGCATTATGGGATGATGAAGCATTTGT
TAGTGATAATACGTTAACAGTAAATGTGAATCGTTTACGAAAAAAATTATCTGAAATTAGTATGGATAGTGCAATCGAAA
CAAAAGTAGGAAAAGGATATATGGCTCATGAATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(149-221)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q99VW2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

40.455

98.214

0.397