Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   D073_RS05835 Genome accession   NZ_CP041145
Coordinates   1118737..1119393 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain At1     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1113737..1124393
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D073_RS05810 (D073_1103) oppF 1114266..1115183 (+) 918 WP_020955632.1 oligopeptide ABC transporter ATP-binding protein OppF -
  D073_RS05815 (D073_1104) - 1115290..1116477 (+) 1188 WP_020955633.1 putative glycoside hydrolase -
  D073_RS05820 (D073_1105) - 1116595..1117173 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  D073_RS05825 (D073_1106) spx 1117352..1117747 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  D073_RS05830 (D073_1107) - 1117805..1118461 (-) 657 WP_007409109.1 TerC family protein -
  D073_RS19485 - 1118644..1118754 (+) 111 Protein_1079 adaptor protein MecA -
  D073_RS05835 (D073_1108) mecA 1118737..1119393 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  D073_RS05840 (D073_1109) - 1119544..1120704 (+) 1161 WP_020955634.1 competence protein CoiA family protein -
  D073_RS05845 (D073_1110) pepF 1120932..1122761 (+) 1830 WP_094031915.1 oligoendopeptidase F Regulator
  D073_RS19490 (D073_1111) - 1122799..1122966 (-) 168 WP_003155026.1 hypothetical protein -
  D073_RS05850 (D073_1112) spxH 1123252..1124154 (-) 903 WP_007409106.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=369810 D073_RS05835 WP_003155032.1 1118737..1119393(+) (mecA) [Bacillus velezensis strain At1]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=369810 D073_RS05835 WP_003155032.1 1118737..1119393(+) (mecA) [Bacillus velezensis strain At1]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment