Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   AANAER_RS04795 Genome accession   NZ_CP041070
Coordinates   959892..961724 (-) Length   610 a.a.
NCBI ID   WP_044415570.1    Uniprot ID   A0A4Q0XVU8
Organism   Halarcobacter anaerophilus strain DSM 24636     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 954892..966724
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AANAER_RS04770 (AANAER_0955) - 955078..955797 (+) 720 WP_129082759.1 2OG-Fe(II) oxygenase -
  AANAER_RS04775 (AANAER_0956) - 955863..956837 (+) 975 WP_044415580.1 zinc transporter ZntB -
  AANAER_RS04780 (AANAER_0957) mgtE 956839..958197 (+) 1359 WP_129082758.1 magnesium transporter -
  AANAER_RS04785 (AANAER_0958) - 958206..958868 (-) 663 WP_129082757.1 tetratricopeptide repeat protein -
  AANAER_RS04790 (AANAER_0959) - 958865..959887 (-) 1023 WP_129082756.1 alanine racemase -
  AANAER_RS04795 (AANAER_0960) uvrC 959892..961724 (-) 1833 WP_044415570.1 excinuclease ABC subunit UvrC Machinery gene
  AANAER_RS04800 (AANAER_0961) - 961825..962511 (+) 687 WP_129082755.1 SOS response-associated peptidase -
  AANAER_RS04805 (AANAER_0962) - 962497..963432 (-) 936 WP_129082754.1 sensor histidine kinase -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 71270.78 Da        Isoelectric Point: 9.4606

>NTDB_id=369332 AANAER_RS04795 WP_044415570.1 959892..961724(-) (uvrC) [Halarcobacter anaerophilus strain DSM 24636]
MNLEEKLKQLPNKAGVYQYFDAKGKLLYIGKAKILKNRVKSYFRFTPKLLPADKLSARIYKMITEVKSLEWIVVPNEHDA
LILENSLIKQLKPKYNILLRDDKTYPYIYIDFNEDFPRLEITRKVLKGKNIKYFGPYSTGARDMLDSIYEIVPLVQKKSC
IKGKEACLFYQIKKCFAPCEGKISKENYAKLVDEALDYIYNKNRLISKLTKKMEEYSSEFRFEEAMKLRDRIKTIEKSQI
HTGMDLATNENIDLFAIESKDSKAVLVRMFFRDGKLASSNHNYIKPNREDISIDLQEAYERAIINYYDNEIPLLPDEIVI
AHEIEDKEEIEEFIKQKFSKKILLNNPKRGKKKEIVNVALNNCKELLRLSAVKDSSSVYSQLQKLFNLEKIPNRFECFDN
SHMMGQATVGAMVTWEEKFVKSDFRHYNLESKDEYSQMRETLLRRVESFEKNPAPDMWVLDGGETLLKLAIDIRNSCGVN
LDIIAIAKEKLDFKAHRAKGSAKDIIYYEKDGLIEKLDLLPSDKRLQFVQRLRDEAHRFAITFHKKQKRREDTQISLLQI
KGIGEAKVKKLLLYFGTFDNIKSAKLEELKDVLNEKDAMLIINYFKSLEG

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=369332 AANAER_RS04795 WP_044415570.1 959892..961724(-) (uvrC) [Halarcobacter anaerophilus strain DSM 24636]
ATGAATTTAGAAGAAAAACTAAAACAACTGCCAAATAAAGCAGGAGTCTACCAATATTTTGATGCAAAAGGAAAACTTCT
TTATATAGGTAAGGCAAAAATACTAAAAAACAGAGTTAAATCATACTTTAGATTTACACCTAAACTATTACCTGCTGATA
AACTTAGTGCCCGAATTTATAAAATGATAACCGAAGTTAAATCTTTAGAATGGATAGTCGTGCCAAACGAGCATGATGCT
TTGATTTTAGAAAATTCATTAATTAAACAACTCAAACCCAAATATAACATACTTTTAAGAGATGATAAAACATATCCTTA
TATTTATATTGATTTTAACGAGGATTTTCCTAGATTGGAAATTACAAGAAAAGTCTTAAAAGGGAAAAATATAAAATATT
TCGGTCCTTATTCAACAGGTGCAAGAGACATGTTAGACTCAATTTACGAGATTGTTCCTTTGGTTCAGAAAAAATCTTGT
ATAAAAGGCAAAGAGGCTTGTCTTTTTTATCAAATCAAAAAGTGTTTTGCTCCTTGTGAAGGAAAGATTTCAAAAGAGAA
TTATGCAAAGTTAGTGGATGAAGCTTTAGACTATATCTATAATAAAAACAGATTAATCTCCAAATTAACAAAAAAAATGG
AAGAGTACAGCAGCGAGTTTAGATTTGAAGAAGCTATGAAATTAAGAGATAGAATAAAAACTATCGAAAAATCGCAAATT
CATACAGGTATGGATTTGGCAACAAATGAAAATATTGATCTTTTTGCAATAGAGAGTAAAGATTCAAAAGCTGTTTTAGT
AAGAATGTTTTTTAGAGACGGGAAATTAGCTTCAAGTAATCACAACTATATAAAACCAAACAGAGAAGATATCTCAATAG
ATTTACAAGAAGCTTACGAAAGAGCTATTATAAACTATTATGACAATGAAATTCCCCTGCTTCCCGATGAAATCGTAATT
GCCCATGAGATTGAAGACAAAGAAGAGATTGAAGAGTTTATAAAACAGAAATTCTCTAAAAAAATTCTTTTAAACAATCC
CAAAAGAGGGAAGAAAAAAGAGATTGTAAATGTTGCATTAAACAACTGTAAAGAGCTTTTAAGGCTCTCAGCAGTAAAAG
ATTCATCTTCCGTATATTCTCAACTTCAAAAACTATTTAATCTTGAAAAAATTCCAAACAGATTTGAGTGTTTTGACAAC
TCTCATATGATGGGACAAGCAACGGTCGGAGCAATGGTAACTTGGGAAGAAAAATTTGTAAAAAGCGATTTTAGGCATTA
TAATCTGGAATCAAAAGATGAATACTCCCAAATGAGAGAAACTCTTTTAAGAAGAGTTGAAAGTTTTGAAAAAAATCCTG
CTCCTGATATGTGGGTTCTTGACGGAGGAGAAACACTACTTAAACTTGCAATAGATATAAGAAACTCTTGCGGTGTAAAT
CTTGATATTATAGCTATTGCCAAAGAAAAACTTGATTTTAAAGCCCACAGGGCAAAAGGTAGTGCAAAAGATATTATCTA
TTATGAAAAAGATGGTTTAATAGAGAAGCTTGATTTATTGCCAAGCGATAAACGTCTGCAATTTGTACAAAGATTAAGAG
ACGAAGCTCATAGATTTGCCATAACATTTCATAAAAAACAGAAAAGAAGAGAAGATACGCAAATTTCTCTTCTTCAAATC
AAAGGTATAGGTGAAGCAAAGGTGAAAAAACTACTTTTATATTTTGGAACATTTGACAATATAAAAAGTGCAAAACTTGA
GGAATTGAAAGATGTTCTAAACGAAAAAGATGCTATGCTTATAATCAATTATTTTAAATCTCTTGAAGGTTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(204-237)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(383-541)

GIY-YIG catalytic domain (GIY-YIG)

(14-96)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4Q0XVU8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

50.836

98.033

0.498

Multiple sequence alignment