Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   FIV54_RS03865 Genome accession   NZ_CP041037
Coordinates   763555..764271 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain NP66     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 758555..769271
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FIV54_RS03845 (FIV54_03850) - 759647..760597 (+) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -
  FIV54_RS03850 (FIV54_03855) - 760746..762230 (+) 1485 WP_000141416.1 sucrose-6-phosphate hydrolase -
  FIV54_RS03855 (FIV54_03860) - 762227..763186 (+) 960 WP_001253309.1 carbohydrate kinase -
  FIV54_RS03860 (FIV54_03865) - 763374..763483 (-) 110 Protein_739 hypothetical protein -
  FIV54_RS03865 (FIV54_03870) agrA 763555..764271 (-) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  FIV54_RS03870 (FIV54_03875) agrC 764290..765573 (-) 1284 WP_145326030.1 quorum-sensing sensor histidine kinase AgrC -
  FIV54_RS03875 (FIV54_03880) agrD 765603..765746 (-) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  FIV54_RS03880 (FIV54_03885) - 765749..766312 (-) 564 WP_001105696.1 accessory gene regulator AgrB -
  FIV54_RS14010 hld 766602..766682 (+) 81 WP_000046022.1 delta-hemolysin -
  FIV54_RS03890 (FIV54_03895) - 767282..768067 (-) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  FIV54_RS03895 (FIV54_03900) - 768428..769054 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=369103 FIV54_RS03865 WP_000688498.1 763555..764271(-) (agrA) [Staphylococcus aureus strain NP66]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=369103 FIV54_RS03865 WP_000688498.1 763555..764271(-) (agrA) [Staphylococcus aureus strain NP66]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGTTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment